hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07512.1
Complex Portal: CPX-24523
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COL21A1 | Collagen alpha-1(XXI) chain | 5 | UniProt NCBI |
| PLOD3 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)] | 5 | UniProt NCBI |
| C1QTNF3 | Complement C1q tumor necrosis factor-related protein 3 (Collagenous repeat-containing sequence 26 kDa protein) (CORS26) (Secretory protein CORS26) | 5 | UniProt NCBI |
| LAIR2 | Leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) (CD antigen CD306) | 4 | UniProt NCBI |
| RITA1 | RBPJ-interacting and tubulin-associated protein 1 (RBPJ-interacting and tubulin-associated protein) | 5 | UniProt NCBI |
| COLGALT1 | Procollagen galactosyltransferase 1 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 1) (ColGalT 1) (Glycosyltransferase 25 family member 1) (Hydroxylysine galactosyltransferase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6997 | 5.12534978153e-05 | 0.333333333333 | PLOD3 COLGALT1 | ADIPOQ-PLOD3-GLT25D1 complex |
| REAC:R-HSA-1650814 | 0.000155019643237 | 0.5 | COL21A1 COLGALT1 PLOD3 | Collagen biosynthesis and modifying enzymes |
| REAC:R-HSA-1474290 | 0.000417052782963 | 0.5 | COL21A1 COLGALT1 PLOD3 | Collagen formation |
| KEGG:00514 | 0.00563154229257 | 0.333333333333 | PLOD3 COLGALT1 | Other types of O-glycan biosynthesis |
| KEGG:00310 | 0.0118953447518 | 0.333333333333 | PLOD3 COLGALT1 | Lysine degradation |
| REAC:R-HSA-1474244 | 0.0133066815994 | 0.5 | COL21A1 COLGALT1 PLOD3 | Extracellular matrix organization |
| GO:0050211 | 0.0210651876021 | 0.333333333333 | PLOD3 COLGALT1 | procollagen galactosyltransferase activity |
| HP:0002132 | 0.0436511011886 | 0.333333333333 | PLOD3 COLGALT1 | Porencephalic cyst |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PLOD3 | COLGALT1 | 1.0 | 0.55 |
structurally_consistent (Q02809)
|
hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| PLOD3 | C1QTNF3 | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PLOD3 | RITA1 | 0.972 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| RITA1 | COLGALT1 | 0.963 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LAIR2 | PLOD3 | 0.959 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| C1QTNF3 | COLGALT1 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| COL21A1 | PLOD3 | 0.957 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| COL21A1 | COLGALT1 | 0.947 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| LAIR2 | COLGALT1 | 0.92 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes