hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07544.1

Complex Portal: CPX-14497

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
DNAJA1	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	5	UniProt NCBI
CDC42EP1	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)	5	UniProt NCBI
TUBB	Tubulin beta chain (Tubulin beta-5 chain)	5	UniProt NCBI
CAD	Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	5	UniProt NCBI
RPS27	Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1)	5	UniProt NCBI
PLD2	Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2)	5	UniProt NCBI
TTC5	Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap)	5	UniProt NCBI
TUBA1A	Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]	5	UniProt NCBI
TUBB4A	Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)	5	UniProt NCBI
TUBA4B	Putative tubulin-like protein alpha-4B (EC 3.6.5.-) (Alpha-tubulin 4B)	3	UniProt NCBI
TUBA1B	Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]	5	UniProt NCBI
TUBB6	Tubulin beta-6 chain (Tubulin beta class V)	5	UniProt NCBI
MADD	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP)	5	UniProt NCBI
TUBB2A	Tubulin beta-2A chain (Tubulin beta class IIa)	5	UniProt NCBI
DNAJA2	DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)	5	UniProt NCBI
TBCD	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)	5	UniProt NCBI
CAPS	Calcyphosin (Calcyphosine)	5	UniProt NCBI
ARL2	ADP-ribosylation factor-like protein 2	5	UniProt NCBI
FAS	Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)	5	UniProt NCBI
TCP11L1	T-complex protein 11-like protein 1	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-389977	2.13179079188e-16	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A ARL2 TBCD	Post-chaperonin tubulin folding pathway
REAC:R-HSA-3371497	3.20887122626e-13	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B DNAJA1 DNAJA2 TUBB2A	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-190840	1.10513351599e-11	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
REAC:R-HSA-190872	1.61396251578e-11	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Transport of connexons to the plasma membrane
REAC:R-HSA-391251	3.86378062892e-11	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A ARL2 TBCD	Protein folding
REAC:R-HSA-9619483	1.04867414762e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Activation of AMPK downstream of NMDARs
REAC:R-HSA-389960	1.04867414762e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Formation of tubulin folding intermediates by CCT/TriC
WP:WP2359	2.07602556604e-10	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	Parkin ubiquitin proteasomal system pathway
REAC:R-HSA-190861	2.22571073023e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Gap junction assembly
REAC:R-HSA-5626467	2.80418835066e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	RHO GTPases activate IQGAPs
REAC:R-HSA-9668328	2.80418835066e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Sealing of the nuclear envelope (NE) by ESCRT-III
REAC:R-HSA-389958	5.33728409145e-10	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REAC:R-HSA-9609736	1.61854787479e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Assembly and cell surface presentation of NMDA receptors
REAC:R-HSA-8955332	1.61854787479e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Carboxyterminal post-translational modifications of tubulin
REAC:R-HSA-190828	1.91136826298e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Gap junction trafficking
REAC:R-HSA-157858	2.24695090732e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Gap junction trafficking and regulation
REAC:R-HSA-9646399	2.63013185057e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Aggrephagy
WP:WP2272	3.40272997537e-09	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Pathogenic Escherichia coli infection
REAC:R-HSA-380320	3.76246611941e-09	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	Recruitment of NuMA to mitotic centrosomes
REAC:R-HSA-437239	5.45816011903e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Recycling pathway of L1
REAC:R-HSA-6811436	9.23143534721e-09	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-983189	1.49580426641e-08	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Kinesins
KEGG:04540	1.59174917317e-08	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Gap junction
REAC:R-HSA-68877	1.73605325463e-08	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	Mitotic Prometaphase
REAC:R-HSA-9648025	1.9128100458e-08	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-2500257	3.10921810654e-08	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-2995410	5.72257729937e-08	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Nuclear Envelope (NE) Reassembly
REAC:R-HSA-5663220	5.75733008688e-08	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	RHO GTPases Activate Formins
REAC:R-HSA-438064	6.27157502024e-08	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Post NMDA receptor activation events
REAC:R-HSA-1445148	6.86361443655e-08	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Translocation of SLC2A4 (GLUT4) to the plasma membrane
CORUM:6713	7.10994807657e-08	0.157894736842	TUBB TBCD ARL2	TBCD-ARL2-tubulin(beta) complex
CORUM:6703	7.10994807657e-08	0.157894736842	TUBB TUBA1A TBCD	TBCD-tubulin(alpha)-tubulin(beta) complex
CORUM:6715	7.10994807657e-08	0.157894736842	TUBB TBCD ARL2	TBCD-ARL2-tubulin(beta)-TBCE complex
REAC:R-HSA-9663891	1.14760789048e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Selective autophagy
REAC:R-HSA-8852276	1.24502104332e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	The role of GTSE1 in G2/M progression after G2 checkpoint
REAC:R-HSA-442755	1.70609803774e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-390466	2.47359983923e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Chaperonin-mediated protein folding
REAC:R-HSA-6811434	4.28480414891e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	COPI-dependent Golgi-to-ER retrograde traffic
REAC:R-HSA-6807878	5.19924748803e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	COPI-mediated anterograde transport
REAC:R-HSA-2467813	5.93831711217e-07	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Separation of Sister Chromatids
GO:0005200	6.28331841941e-07	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	structural constituent of cytoskeleton
KEGG:04145	6.94440142632e-07	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Phagosome
REAC:R-HSA-5617833	7.16042102027e-07	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	Cilium Assembly
REAC:R-HSA-69275	7.16042102027e-07	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	G2/M Transition
REAC:R-HSA-373760	7.51733335207e-07	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	L1CAM interactions
REAC:R-HSA-453274	7.70595381949e-07	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	Mitotic G2-G2/M phases
GO:0005874	9.21569301201e-07	0.473684210526	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B TUBB2A TUBB TBCD	microtubule
GO:0005525	1.21577190044e-06	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB ARL2	GTP binding
REAC:R-HSA-5620924	1.41959646942e-06	0.263157894737	TUBA1B TUBB6 TUBA1A TUBB2A TUBB4A	Intraflagellar transport
REAC:R-HSA-2132295	1.7260725399e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	MHC class II antigen presentation
REAC:R-HSA-9609690	2.01126317577e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	HCMV Early Events
REAC:R-HSA-68882	2.26274058068e-06	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Mitotic Anaphase
REAC:R-HSA-2555396	2.33403531107e-06	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Mitotic Metaphase and Anaphase
KEGG:04814	2.36948916637e-06	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Motor proteins
KEGG:05130	2.64371876876e-06	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Pathogenic Escherichia coli infection
REAC:R-HSA-1632852	2.69942385375e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Macroautophagy
REAC:R-HSA-8856688	2.69942385375e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Golgi-to-ER retrograde transport
GO:0032561	3.0205359614e-06	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB ARL2	guanyl ribonucleotide binding
GO:0019001	3.14626059482e-06	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB ARL2	guanyl nucleotide binding
REAC:R-HSA-68886	3.94310056581e-06	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	M Phase
REAC:R-HSA-9612973	5.30909582283e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Autophagy
REAC:R-HSA-9609646	5.53906742701e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	HCMV Infection
REAC:R-HSA-199977	5.77721805045e-06	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	ER to Golgi Anterograde Transport
REAC:R-HSA-194315	9.11300785171e-06	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A PLD2 TUBA4B TUBB2A RPS27 CDC42EP1	Signaling by Rho GTPases
REAC:R-HSA-1852241	9.62206804376e-06	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB	Organelle biogenesis and maintenance
REAC:R-HSA-983231	1.01063986178e-05	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Factors involved in megakaryocyte development and platelet production
REAC:R-HSA-112314	1.04972693633e-05	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Neurotransmitter receptors and postsynaptic signal transmission
REAC:R-HSA-389957	1.0517184726e-05	0.210526315789	TUBB2A TUBB6 TUBA1A TUBB4A	Prefoldin mediated transfer of substrate to CCT/TriC
REAC:R-HSA-9716542	1.10212470593e-05	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A PLD2 TUBA4B TUBB2A RPS27 CDC42EP1	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
REAC:R-HSA-195258	1.59485894911e-05	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	RHO GTPase Effectors
KEGG:05132	1.62065587468e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Salmonella infection
REAC:R-HSA-948021	1.74206927962e-05	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Transport to the Golgi and subsequent modification
KEGG:05012	2.31588879137e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Parkinson disease
KEGG:05020	2.74601530844e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Prion disease
REAC:R-HSA-2262752	2.98680400455e-05	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B DNAJA1 TUBB2A DNAJA2 RPS27	Cellular responses to stress
REAC:R-HSA-8953897	3.24433126594e-05	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B DNAJA1 TUBB2A DNAJA2 RPS27	Cellular responses to stimuli
REAC:R-HSA-6811442	3.45487062432e-05	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Intra-Golgi and retrograde Golgi-to-ER traffic
GO:0035639	4.12492092443e-05	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	purine ribonucleoside triphosphate binding
WP:WP2059	4.1826197601e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Alzheimer 39 s disease and miRNA effects
WP:WP5124	4.1826197601e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Alzheimer 39 s disease
REAC:R-HSA-69278	4.25628612096e-05	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	Cell Cycle, Mitotic
GO:0099513	4.30279749644e-05	0.473684210526	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B TUBB2A TUBB TBCD	polymeric cytoskeletal fiber
REAC:R-HSA-112315	4.66032970475e-05	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Transmission across Chemical Synapses
KEGG:05016	4.95905553501e-05	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Huntington disease
REAC:R-HSA-5610787	5.58840290943e-05	0.263157894737	TUBA1B TUBB6 TUBA1A TUBB2A TUBB4A	Hedgehog 'off' state
CORUM:6455	6.11162772017e-05	0.105263157895	TBCD ARL2	ARL2-TBCD complex
CORUM:6697	6.11162772017e-05	0.105263157895	TBCD ARL2	ARL2-TBCD complex
GO:0032555	0.000127386919528	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	purine ribonucleotide binding
KEGG:05014	0.000140296610675	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Amyotrophic lateral sclerosis
GO:0032553	0.000147536069697	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	ribonucleotide binding
REAC:R-HSA-5358351	0.00016868161571	0.263157894737	TUBA1B TUBB6 TUBA1A TUBB2A TUBB4A	Signaling by Hedgehog
GO:0000226	0.000179806025826	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A ARL2 TUBB TBCD	microtubule cytoskeleton organization
KEGG:05010	0.000185451107359	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Alzheimer disease
REAC:R-HSA-1640170	0.000207226832731	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	Cell Cycle
REAC:R-HSA-446203	0.000328539559615	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Asparagine N-linked glycosylation
GO:0017076	0.000373588750927	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	purine nucleotide binding
GO:0015630	0.000383206650991	0.578947368421	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B DNAJA1 ARL2 TUBB TBCD TUBB2A	microtubule cytoskeleton
REAC:R-HSA-9824446	0.000388584221139	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	Viral Infection Pathways
REAC:R-HSA-422475	0.000434363424711	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Axon guidance
REAC:R-HSA-112316	0.000443922741798	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Neuronal System
GO:0099512	0.000522304703444	0.473684210526	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B TUBB2A TUBB TBCD	supramolecular fiber
REAC:R-HSA-9675108	0.00055493800606	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Nervous system development
KEGG:05022	0.000575301221829	0.315789473684	TUBA1A TUBA1B TUBB4A TUBB6 TUBB2A TUBB	Pathways of neurodegeneration - multiple diseases
GO:0099081	0.000582314924558	0.473684210526	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B TUBB2A TUBB TBCD	supramolecular polymer
GO:0007010	0.000917146793222	0.578947368421	TUBA1A TUBB6 TUBA1B TUBB4A PLD2 TUBA4B TUBB2A ARL2 TUBB TBCD CDC42EP1	cytoskeleton organization
GO:0000166	0.00125271010498	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	nucleotide binding
GO:1901265	0.00127044280565	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	nucleoside phosphate binding
REAC:R-HSA-5663205	0.00182133108374	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	Infectious disease
GO:0005856	0.00199995776398	0.631578947368	TUBA1A TUBB6 TCP11L1 TUBB4A TUBA1B TUBB2A TUBA4B DNAJA1 ARL2 TUBB TBCD CDC42EP1	cytoskeleton
GO:1901363	0.00227521143438	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	heterocyclic compound binding
GO:0097367	0.00294341364322	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	carbohydrate derivative binding
GO:0007017	0.00350816207738	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A ARL2 TUBB TBCD	microtubule-based process
GO:0005198	0.00551955690467	0.421052631579	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB RPS27	structural molecule activity
REAC:R-HSA-109582	0.0113749121595	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Hemostasis
GO:0043168	0.0130466812313	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A TUBB CAD ARL2	anion binding
HP:0025102	0.0177502656521	0.105263157895	TUBB TUBA1A	Dysgenesis of the basal ganglia
REAC:R-HSA-1266738	0.0184083204018	0.368421052632	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A RPS27	Developmental Biology
REAC:R-HSA-199991	0.0185644215314	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Membrane Trafficking
REAC:R-HSA-162582	0.0212190849404	0.526315789474	TUBA1A TUBB6 TUBA1B TUBB4A PLD2 TUBA4B TUBB2A ARL2 RPS27 CDC42EP1	Signal Transduction
GO:0043167	0.022396119831	0.578947368421	TUBA1A TUBB6 TUBA1B TUBB4A RPS27 TUBA4B TUBB2A CAPS TUBB CAD ARL2	ion binding
REAC:R-HSA-380259	0.0242342000008	0.157894736842	TUBB TUBA1A TUBB4A	Loss of Nlp from mitotic centrosomes
REAC:R-HSA-380284	0.0242342000008	0.157894736842	TUBB TUBA1A TUBB4A	Loss of proteins required for interphase microtubule organization from the centrosome
GO:0099080	0.0246795742159	0.473684210526	TUBA1A TUBB6 TCP11L1 TUBA1B TUBB4A TUBA4B TUBB2A TUBB TBCD	supramolecular complex
REAC:R-HSA-5653656	0.0251197818283	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Vesicle-mediated transport
REAC:R-HSA-8854518	0.0276792201032	0.157894736842	TUBB TUBA1A TUBB4A	AURKA Activation by TPX2
HPA:0461423	0.0310232209503	0.157894736842	TUBB2A TUBA1A TUBA1B	skin 1; eccrine glands[High]
REAC:R-HSA-392499	0.0367575689349	0.473684210526	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A ARL2 TBCD RPS27	Metabolism of proteins
REAC:R-HSA-380270	0.0398941166488	0.157894736842	TUBB TUBA1A TUBB4A	Recruitment of mitotic centrosome proteins and complexes
REAC:R-HSA-380287	0.0398941166488	0.157894736842	TUBB TUBA1A TUBB4A	Centrosome maturation
REAC:R-HSA-1280218	0.0420111473439	0.315789473684	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B TUBB2A	Adaptive Immune System
GO:0007049	0.0475887003223	0.526315789474	TUBA1A TUBB6 TUBA1B TUBB4A TUBA4B MADD TUBB2A ARL2 TUBB TBCD	cell cycle
REAC:R-HSA-2565942	0.0479847199721	0.157894736842	TUBB TUBA1A TUBB4A	Regulation of PLK1 Activity at G2/M Transition

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ARL2	TBCD	1.0	0.2
DNAJA2	DNAJA1	1.0	0.382	mutually_exclusive (Q14249)
DNAJA1	TUBB	0.999	0.374
DNAJA2	TUBB	0.999	0.536
TUBB	TBCD	0.999	0.4
TCP11L1	TUBB	0.999	0.204105263158
TUBB2A	TUBB6	0.999	0.526	structurally_consistent (dimer)
ARL2	TUBB	0.998	0.098
TUBB	CAD	0.998	0.352
TUBB2A	CDC42EP1	0.996	0.192703448276
TUBB6	TUBB	0.996	0.982	mutually_exclusive (Q9BQE3)
TUBB2A	TUBB4A	0.996	0.684	structurally_consistent (dimer)
TUBA1B	TUBB	0.995
TUBB2A	FAS	0.995	0.204	structurally_consistent (P04350) structurally_consistent (dimer)
TUBB2A	TBCD	0.995	0.148
TUBB4A	TBCD	0.993	0.3
TCP11L1	TTC5	0.993	0.04
DNAJA1	TUBA1B	0.993		mutually_exclusive (P68366)
TUBB2A	TUBB	0.993	0.626	structurally_consistent (dimer)
CDC42EP1	TUBB4A	0.993	0.284
PLD2	TUBB	0.992	0.516
TUBB	TUBB4A	0.992	0.938	structurally_consistent (dimer)
TUBB6	TUBB4A	0.992	0.798
TUBB	FAS	0.992	0.112	mutually_exclusive (P04350)
TCP11L1	TUBB4A	0.991	0.138
TUBB2A	TTC5	0.991	0.188	structurally_consistent (dimer)
RPS27	TUBB6	0.99	0.256
RPS27	TUBB	0.99	0.49	structurally_consistent (Q3ZCM7)
TUBB2A	ARL2	0.989	0.164
CDC42EP1	TUBB	0.988	0.358
TUBB	TTC5	0.985	0.236
TUBB2A	TCP11L1	0.983	0.106	structurally_consistent (dimer)
TUBA1A	TUBB4A	0.982
TUBA1A	TUBB	0.979
TUBA1B	TUBB6	0.977
TUBB6	FAS	0.975	0.224768
RPS27	TUBB4A	0.975	0.264	structurally_consistent (Q3ZCM7)
DNAJA1	TUBA1A	0.968
TUBA1A	TUBA1B	0.967
TUBB2A	TUBA1A	0.966		structurally_consistent (dimer)
MADD	TUBB2A	0.966	0.116
TUBB6	TTC5	0.966	0.198
DNAJA2	PLD2	0.962	0.092
DNAJA2	TUBB4A	0.958	0.242
RPS27	TUBA1A	0.957
FAS	TBCD	0.956	0.149666666667
CAPS	TUBB6	0.956	0.3
DNAJA2	TUBB6	0.955	0.21
CAPS	TUBB	0.952	0.306608695652
DNAJA2	TUBA1B	0.949
TUBB4A	FAS	0.947	0.164609230769	structurally_consistent (dimer)
TUBB2A	CAPS	0.947	0.138	structurally_consistent (dimer)
TCP11L1	CDC42EP1	0.943	0.106
TCP11L1	TUBB6	0.938	0.152
RPS27	CAD	0.934	0.162
ARL2	TTC5	0.934	0.064
TCP11L1	ARL2	0.932	0.052
CDC42EP1	TTC5	0.93	0.078
DNAJA2	TUBA1A	0.926		structurally_consistent (dimer)
CDC42EP1	TUBA1A	0.925
DNAJA2	CDC42EP1	0.924	0.092
DNAJA1	PLD2	0.92	0.096
TUBA1A	TTC5	0.92
ARL2	TUBB4A	0.919	0.188
TCP11L1	TUBA1A	0.916
ARL2	FAS	0.906	0.166
TTC5	FAS	0.899	0.11
CDC42EP1	TUBB6	0.886	0.226042553191
PLD2	CAD	0.88	0.232
DNAJA1	TUBB6	0.867	0.298
DNAJA1	TUBB4A	0.866	0.22
TUBB2A	TUBA1B	0.864
MADD	TUBB4A	0.864	0.142
TUBB2A	PLD2	0.829	0.212
DNAJA1	RPS27	0.823	0.238	structurally_consistent (P68366)
CAPS	TUBB4A	0.812	0.18
MADD	TUBB	0.811	0.263846153846
TUBA1A	TUBB6	0.805
MADD	TUBA1A	0.798
TCP11L1	TBCD	0.792	0.048	structurally_consistent (Q9BVA1)
TCP11L1	DNAJA2	0.774	0.078
DNAJA2	RPS27	0.752	0.348
CDC42EP1	TUBA1B	0.751
DNAJA2	CAD	0.746	0.282
TUBA1B	CAD	0.74
TTC5	TBCD	0.739	0.036
MADD	CDC42EP1	0.738	0.068
MADD	FAS	0.725	0.038
TUBB2A	DNAJA1	0.722	0.16
ARL2	TUBB6	0.716	0.1803
TUBA1A	CAD	0.692
MADD	PLD2	0.674	0.136
MADD	TCP11L1	0.655	0.066
PLD2	TUBB4A	0.652	0.240861111111
TUBB2A	DNAJA2	0.649	0.438
MADD	TUBB6	0.633	0.198
RPS27	TUBA1B	0.628
TUBB4A	TTC5	0.614	0.312888888889
PLD2	TUBA1B	0.606
TCP11L1	FAS	0.604	0.112
MADD	TBCD	0.592	0.062
TUBB2A	CAD	0.591	0.314
TUBB2A	RPS27	0.587	0.17
ARL2	CDC42EP1	0.586	0.082
MADD	DNAJA2	0.554	0.13
ARL2	PLD2	0.534	0.074
PLD2	TUBA1A	0.521
TCP11L1	DNAJA1	0.51	0.084
DNAJA1	CAD	0.506	0.23
RPS27	TBCD	0.5	0.282
MADD	TTC5	0.443	0.098
PLD2	TTC5	0.439	0.154
TUBA1B	TUBB4A	0.432
TUBA1A	CAPS	0.429
TCP11L1	CAD	0.395	0.058
CAD	TUBB4A	0.353	0.294
RPS27	CDC42EP1	0.342	0.186
MADD	CAD	0.334	0.12
ARL2	CAPS	0.303	0.062
DNAJA1	CDC42EP1	0.301	0.174
TUBA1B	TBCD	0.288
PLD2	TBCD	0.284	0.104
MADD	DNAJA1	0.281	0.076
MADD	ARL2	0.255	0.114
CDC42EP1	TBCD	0.247	0.12
TUBB6	TBCD	0.243	0.252
TUBA1A	TBCD	0.226
PLD2	FAS	0.204	0.138
MADD	RPS27	0.201	0.138
CAPS	TBCD	0.169	0.118
ARL2	TUBA1A	0.167
CDC42EP1	CAD	0.156	0.164
DNAJA1	TTC5	0.154	0.128
CAPS	TTC5	0.137	0.072
PLD2	RPS27	0.131	0.154
TCP11L1	CAPS	0.127	0.1
RPS27	TTC5	0.127	0.21
PLD2	TUBB6	0.116	0.264
TUBA1A	FAS	0.113
TUBB6	CAD	0.102	0.272
ARL2	RPS27	0.089	0.144	structurally_consistent (Q3ZCM7)
DNAJA1	FAS	0.084	0.12
RPS27	FAS	0.083	0.202
ARL2	DNAJA1	0.079	0.094
CAPS	FAS	0.066	0.048	structurally_consistent (Q13885)
DNAJA2	FAS	0.063	0.157157894737
DNAJA2	TBCD	0.058	0.182
PLD2	CDC42EP1	0.054	0.184
PLD2	CAPS	0.053	0.132
CDC42EP1	CAPS	0.053	0.06
TCP11L1	RPS27	0.052	0.078	structurally_consistent (P68366)
DNAJA1	TBCD	0.051	0.226
DNAJA2	ARL2	0.051	0.086	structurally_consistent (Q3ZCM7)
CAD	TBCD	0.05	0.418
CAD	TTC5	0.044	0.1
DNAJA2	TTC5	0.04	0.1565
TUBA1B	TTC5	0.029
TUBA1B	FAS	0.027
MADD	CAPS	0.023	0.066
TCP11L1	PLD2	0.02	0.094
DNAJA1	CAPS	0.019	0.14
ARL2	CAD	0.016	0.07
CDC42EP1	FAS	0.015	0.174
TCP11L1	TUBA1B	0.015
DNAJA2	CAPS	0.015	0.228
RPS27	CAPS	0.013	0.148
CAD	FAS	0.01	0.086
TUBA1B	CAPS	0.009
MADD	TUBA1B	0.008
CAPS	CAD	0.005	0.1
ARL2	TUBA1B	0.001

Related Complexes

Genename	Complexes
DNAJA1	huMAP3_01335.1 huMAP3_02724.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10363.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
CDC42EP1	huMAP3_01878.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_08981.1 huMAP3_09233.1 huMAP3_09670.1 huMAP3_09835.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11719.1
TUBB	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
CAD	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10103.1 huMAP3_10475.1 huMAP3_10665.1
RPS27	huMAP3_01409.1 huMAP3_01838.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08023.1 huMAP3_08179.1 huMAP3_08373.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
PLD2	huMAP3_01335.1 huMAP3_01541.1 huMAP3_03106.1 huMAP3_03228.1 huMAP3_04629.1 huMAP3_05710.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_08225.1 huMAP3_08361.1 huMAP3_09233.1 huMAP3_10018.1 huMAP3_10363.1 huMAP3_10475.1
TTC5	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1 huMAP3_14884.1
TUBA1A	huMAP3_02724.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBB4A	huMAP3_05787.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA4B	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA1B	huMAP3_02724.1 huMAP3_03810.1 huMAP3_06559.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_07938.1 huMAP3_08094.1 huMAP3_08179.1 huMAP3_09191.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10656.1 huMAP3_10665.1 huMAP3_11156.1 huMAP3_14584.1
TUBB6	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
MADD	huMAP3_00118.1 huMAP3_00962.1 huMAP3_05951.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_11346.1
TUBB2A	huMAP3_00118.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
DNAJA2	huMAP3_00648.1 huMAP3_01335.1 huMAP3_03394.1 huMAP3_05710.1 huMAP3_07544.1 huMAP3_08225.1 huMAP3_10363.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_15194.1
TBCD	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
CAPS	huMAP3_03106.1 huMAP3_03532.1 huMAP3_04859.1 huMAP3_06197.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11669.1 huMAP3_12525.1 huMAP3_13292.1 huMAP3_14468.1 huMAP3_14491.1 huMAP3_14682.1
ARL2	huMAP3_01239.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10142.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_13133.1 huMAP3_14311.1 huMAP3_14884.1
FAS	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12841.1 huMAP3_14311.1
TCP11L1	huMAP3_00374.1 huMAP3_05787.1 huMAP3_06064.1 huMAP3_07544.1 huMAP3_07625.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10547.1 huMAP3_10665.1 huMAP3_11283.1 huMAP3_14236.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07544.1

Complex Portal: CPX-14497