hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07590.1

Complex Portal: CPX-14427

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
COPS5	COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)	5	UniProt NCBI
KLHL13	Kelch-like protein 13 (BTB and kelch domain-containing protein 2)	5	UniProt NCBI
LRR1	Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5)	5	UniProt NCBI
GPS1	COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)	5	UniProt NCBI
DCAF4	DDB1- and CUL4-associated factor 4 (WD repeat-containing protein 21A)	5	UniProt NCBI
BTBD2	BTB/POZ domain-containing protein 2	5	UniProt NCBI
CUL2	Cullin-2 (CUL-2)	5	UniProt NCBI
FEM1C	Protein fem-1 homolog C (FEM1c) (FEM1-gamma)	5	UniProt NCBI
DDB2	DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)	5	UniProt NCBI
FEM1B	Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)	5	UniProt NCBI
CUL3	Cullin-3 (CUL-3)	5	UniProt NCBI
COPS4	COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)	5	UniProt NCBI
DCAF16	DDB1- and CUL4-associated factor 16	4	UniProt NCBI
DCAF6	DDB1- and CUL4-associated factor 6 (Androgen receptor complex-associated protein) (ARCAP) (IQ motif and WD repeat-containing protein 1) (Nuclear receptor interaction protein) (NRIP)	5	UniProt NCBI
APPBP2	Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1)	5	UniProt NCBI
ERCC8	DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)	5	UniProt NCBI
ANKRD39	Ankyrin repeat domain-containing protein 39	2	UniProt NCBI
BTBD1	BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)	5	UniProt NCBI
KLHL24	Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)	5	UniProt NCBI
COPS9	COP9 signalosome complex subunit 9 (CSN acidic protein) (CSNAP) (Myeloma-overexpressed gene 2 protein)	5	UniProt NCBI
FBXO17	F-box only protein 17 (F-box only protein 26)	5	UniProt NCBI
KCTD20	BTB/POZ domain-containing protein KCTD20 (Potassium channel tetramerization domain containing 20)	3	UniProt NCBI
BTBD10	BTB/POZ domain-containing protein 10 (Glucose metabolism-related protein 1)	4	UniProt NCBI
KLHL18	Kelch-like protein 18	4	UniProt NCBI
KLHL42	Kelch-like protein 42 (Cullin-3-binding protein 9) (Ctb9) (Kelch domain-containing protein 5)	5	UniProt NCBI
DCAF11	DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8951664	5.19727872783e-25	0.692307692308	CUL3 CUL2 DCAF4 GPS1 ERCC8 FEM1C DCAF16 DDB2 DCAF6 COPS5 KLHL42 BTBD1 KLHL13 FEM1B COPS4 FBXO17 DCAF11 LRR1	Neddylation
GO:0031461	1.62554037824e-18	0.576923076923	CUL2 FEM1C FEM1B ERCC8 DCAF16 DDB2 DCAF6 DCAF4 KLHL42 KLHL13 FBXO17 KLHL24 APPBP2 DCAF11 CUL3	cullin-RING ubiquitin ligase complex
GO:0000151	3.39171216186e-15	0.576923076923	CUL2 FEM1C FEM1B ERCC8 DCAF16 DDB2 DCAF6 DCAF4 KLHL42 KLHL13 FBXO17 KLHL24 APPBP2 DCAF11 CUL3	ubiquitin ligase complex
REAC:R-HSA-597592	1.04382865546e-11	0.692307692308	CUL3 CUL2 DCAF4 GPS1 ERCC8 FEM1C DCAF16 DDB2 DCAF6 COPS5 KLHL42 BTBD1 KLHL13 FEM1B COPS4 FBXO17 DCAF11 LRR1	Post-translational protein modification
REAC:R-HSA-392499	2.94648365157e-09	0.692307692308	CUL3 CUL2 DCAF4 GPS1 ERCC8 FEM1C DCAF16 DDB2 DCAF6 COPS5 KLHL42 BTBD1 KLHL13 FEM1B COPS4 FBXO17 DCAF11 LRR1	Metabolism of proteins
GO:1990234	1.49914102663e-08	0.576923076923	CUL2 FEM1C FEM1B ERCC8 DCAF16 DDB2 DCAF6 DCAF4 KLHL42 KLHL13 FBXO17 KLHL24 APPBP2 DCAF11 CUL3	transferase complex
GO:0140535	3.45950330463e-08	0.576923076923	CUL2 FEM1C FEM1B ERCC8 DCAF16 DDB2 DCAF6 DCAF4 KLHL42 KLHL13 FBXO17 KLHL24 APPBP2 DCAF11 CUL3	intracellular protein-containing complex
CORUM:728	1.85434097549e-07	0.153846153846	COPS5 ERCC8 COPS4 GPS1	CSA-POLIIa complex
CORUM:727	1.85434097549e-07	0.153846153846	COPS5 ERCC8 COPS4 GPS1	CSA complex
CORUM:726	1.85434097549e-07	0.153846153846	COPS5 COPS4 DDB2 GPS1	DDB2 complex
GO:0080008	1.60086393418e-06	0.230769230769	DDB2 DCAF6 DCAF16 DCAF4 ERCC8 DCAF11	Cul4-RING E3 ubiquitin ligase complex
GO:0032446	4.638957979e-06	0.461538461538	KLHL18 CUL3 DDB2 GPS1 ERCC8 KLHL42 COPS5 COPS9 KLHL13 COPS4 KLHL24 CUL2	protein modification by small protein conjugation
CORUM:2174	1.33775656281e-05	0.115384615385	COPS5 COPS4 GPS1	COP9 signalosome complex
CORUM:2715	1.33775656281e-05	0.115384615385	GPS1 CUL2 CUL3	Ubiquitin E3 ligase (CSN1, CSN8, HRT1, SKP1, SKP2, CUL1, CUL2, CUL3)
GO:0070647	1.44930457099e-05	0.461538461538	KLHL18 CUL3 DDB2 GPS1 ERCC8 KLHL42 COPS5 COPS9 KLHL13 COPS4 KLHL24 CUL2	protein modification by small protein conjugation or removal
CORUM:2179	2.00426622432e-05	0.115384615385	COPS5 COPS4 GPS1	CNS-P53 complex
GO:0043687	3.07800632541e-05	0.461538461538	KLHL18 CUL3 DDB2 GPS1 ERCC8 KLHL42 COPS5 COPS9 KLHL13 COPS4 KLHL24 CUL2	post-translational protein modification
REAC:R-HSA-983168	0.000138782723847	0.269230769231	CUL2 KLHL13 LRR1 KLHL42 BTBD1 FBXO17 CUL3	Antigen processing: Ubiquitination & Proteasome degradation
CORUM:7533	0.000146312725026	0.0769230769231	CUL3 KLHL42	Ubiquitin E3 ligase (CUL3, KLHL42)
GO:0043161	0.000165032430194	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	proteasome-mediated ubiquitin-dependent protein catabolic process
REAC:R-HSA-5696394	0.00017419301719	0.153846153846	COPS5 COPS4 DDB2 GPS1	DNA Damage Recognition in GG-NER
KEGG:04120	0.000229952391836	0.192307692308	DDB2 ERCC8 CUL3 KLHL13 CUL2	Ubiquitin mediated proteolysis
GO:1902494	0.000230513975059	0.576923076923	CUL2 FEM1C FEM1B ERCC8 DCAF16 DDB2 DCAF6 DCAF4 KLHL42 KLHL13 FBXO17 KLHL24 APPBP2 DCAF11 CUL3	catalytic complex
REAC:R-HSA-5696398	0.000364673698035	0.192307692308	COPS5 ERCC8 COPS4 DDB2 GPS1	Nucleotide Excision Repair
CORUM:7525	0.000438457574873	0.0769230769231	KLHL24 CUL3	Ubiquitin E3 ligase (CUL3, KLHL24, RBX1)
REAC:R-HSA-983169	0.000547178569059	0.269230769231	CUL2 KLHL13 LRR1 KLHL42 BTBD1 FBXO17 CUL3	Class I MHC mediated antigen processing & presentation
REAC:R-HSA-6781823	0.000628180188053	0.153846153846	COPS5 ERCC8 COPS4 GPS1	Formation of TC-NER Pre-Incision Complex
CORUM:7523	0.000875955084067	0.0769230769231	KLHL13 CUL3	Ubiquitin E3 ligase (CUL3, KLHL9, KLHL13, RBX1)
GO:0010498	0.00132137694247	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	proteasomal protein catabolic process
GO:2000434	0.00149739733317	0.153846153846	COPS5 COPS9 COPS4 GPS1	regulation of protein neddylation
GO:0031462	0.00230659011084	0.153846153846	FEM1C APPBP2 CUL2 FEM1B	Cul2-RING ubiquitin ligase complex
REAC:R-HSA-9013422	0.00270164433557	0.115384615385	GPS1 CUL3 COPS4	RHOBTB1 GTPase cycle
REAC:R-HSA-6781827	0.0030468477726	0.153846153846	COPS5 ERCC8 COPS4 GPS1	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
REAC:R-HSA-5696399	0.00410750653605	0.153846153846	COPS5 COPS4 DDB2 GPS1	Global Genome Nucleotide Excision Repair (GG-NER)
GO:0006511	0.00475560727773	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	ubiquitin-dependent protein catabolic process
GO:0019941	0.00545959192527	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	modification-dependent protein catabolic process
GO:0043632	0.00657557873027	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	modification-dependent macromolecule catabolic process
GO:0045116	0.00671494196239	0.153846153846	COPS5 COPS9 COPS4 GPS1	protein neddylation
REAC:R-HSA-9706574	0.00984389730861	0.115384615385	GPS1 CUL3 COPS4	RHOBTB GTPase Cycle
GO:0008180	0.0136762530452	0.153846153846	COPS5 COPS9 COPS4 GPS1	COP9 signalosome
HPA:0060842	0.0147394187488	0.230769230769	LRR1 KCTD20 APPBP2 DDB2 BTBD10 ANKRD39	bronchus; basal cells[>=Medium]
GO:0051603	0.0275387463887	0.346153846154	CUL3 FEM1B APPBP2 KLHL42 FEM1C ERCC8 FBXO17 DCAF11 CUL2	proteolysis involved in protein catabolic process
GO:0000338	0.0297425210859	0.115384615385	COPS5 COPS4 GPS1	protein deneddylation
GO:0031463	0.0310187089891	0.153846153846	KLHL24 KLHL42 KLHL13 CUL3	Cul3-RING ubiquitin ligase complex
WP:WP5114	0.0350760112351	0.115384615385	GPS1 ERCC8 DDB2	Nucleotide excision repair in xeroderma pigmentosum
REAC:R-HSA-1280218	0.0373215595907	0.269230769231	CUL2 KLHL13 LRR1 KLHL42 BTBD1 FBXO17 CUL3	Adaptive Immune System
GO:0140627	0.0408476954791	0.115384615385	FEM1C CUL2 FEM1B	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
BTBD1	COPS4	1.0	0.168
LRR1	GPS1	1.0	0.19
GPS1	DCAF4	1.0	0.086
CUL3	GPS1	1.0	0.66
GPS1	COPS4	1.0	0.91	structurally_consistent (dimer)
GPS1	DDB2	1.0	0.21	mutually_exclusive (Q9H9Q2)
BTBD1	BTBD2	1.0	0.13	mixed_interface
LRR1	COPS4	1.0	0.112
GPS1	COPS5	0.999	0.942
DCAF4	COPS5	0.999	0.084
CUL2	GPS1	0.999	0.662	structurally_consistent (P61201)
GPS1	BTBD2	0.999	0.312	structurally_consistent (P61201)
COPS4	DDB2	0.999	0.088
DCAF4	COPS4	0.999	0.1
BTBD1	GPS1	0.999	0.162
CUL2	FEM1B	0.999	0.114
COPS9	GPS1	0.999	0.122
CUL2	COPS4	0.999	0.51
DCAF4	DDB2	0.999	0.094	mutually_exclusive (Q16531)
GPS1	DCAF11	0.999	0.158
BTBD2	COPS4	0.999	0.26
CUL2	APPBP2	0.999	0.214
LRR1	DCAF4	0.999	0.106
GPS1	FEM1B	0.999	0.124
DCAF4	DCAF11	0.999	0.048	mutually_exclusive (Q16531)
COPS5	DDB2	0.999	0.142
CUL2	LRR1	0.999	0.18
COPS5	COPS4	0.999	0.964
BTBD2	COPS5	0.998	0.506
DCAF11	DDB2	0.998	0.176	mutually_exclusive (Q16531)
GPS1	APPBP2	0.998	0.132
KLHL42	CUL3	0.998	0.178	structurally_consistent (dimer)
DCAF11	COPS4	0.998	0.134	mutually_exclusive (Q15843)
BTBD1	COPS5	0.998	0.32	structurally_consistent (dimer)
COPS9	COPS5	0.998	0.094
DCAF11	COPS5	0.998	0.14	mutually_exclusive (Q15843)
COPS5	FBXO17	0.997	0.118
CUL3	BTBD1	0.997	0.225870002477	mixed_interface
CUL2	DCAF4	0.997	0.206
CUL3	BTBD2	0.997	0.33317571885	mixed_interface
CUL2	COPS5	0.997	0.64	structurally_consistent (Q9BQ90)
CUL2	BTBD1	0.997	0.118
KLHL18	GPS1	0.996	0.308
KLHL13	CUL3	0.996	0.176230769231	structurally_consistent (dimer)
LRR1	COPS5	0.995	0.162
BTBD1	DDB2	0.995	0.088
ANKRD39	GPS1	0.995	0.106
BTBD1	LRR1	0.994	0.114
KLHL42	GPS1	0.994	0.312
FEM1C	GPS1	0.994
DCAF6	GPS1	0.994	0.192	structurally_consistent (dimer)
BTBD2	DDB2	0.994	0.238
FBXO17	COPS4	0.993	0.1	structurally_consistent (dimer)
COPS9	COPS4	0.993	0.102
ANKRD39	COPS4	0.992	0.112	structurally_consistent (dimer)
GPS1	FBXO17	0.992	0.152
CUL3	COPS4	0.991	0.378	structurally_consistent (dimer)
KCTD20	COPS4	0.991	0.09	mutually_exclusive (Q13618)
LRR1	BTBD2	0.991	0.08
LRR1	FEM1B	0.991	0.158
COPS9	APPBP2	0.991	0.104
KLHL24	CUL3	0.991		structurally_consistent (dimer)
COPS9	BTBD2	0.991	0.176
FEM1C	CUL2	0.99
BTBD10	BTBD1	0.99	0.144	mutually_exclusive (Q13618)
ERCC8	GPS1	0.99	0.142
KCTD20	BTBD1	0.99	0.102	mutually_exclusive (Q13618)
KCTD20	GPS1	0.989	0.108
CUL3	COPS5	0.989	0.684
BTBD10	COPS4	0.988	0.147	mutually_exclusive (Q13618)
LRR1	DDB2	0.988	0.138
KCTD20	BTBD10	0.987	0.09	mutually_exclusive (Q13618)
KCTD20	CUL3	0.987	0.186	structurally_consistent (dimer)
CUL2	COPS9	0.987	0.056
FEM1B	COPS4	0.987	0.118
CUL2	BTBD2	0.987	0.296
KLHL24	BTBD10	0.987		mutually_exclusive (Q13618)
BTBD10	GPS1	0.987	0.128
BTBD1	DCAF11	0.987	0.056
COPS9	DCAF11	0.986	0.068
BTBD10	KLHL42	0.986	0.1	mutually_exclusive (Q13618)
BTBD1	DCAF4	0.985	0.078
COPS9	BTBD1	0.985	0.106	structurally_consistent (Q9UNS2)
CUL3	COPS9	0.984	0.096
KLHL13	GPS1	0.984	0.226
KLHL42	BTBD1	0.984	0.074	mutually_exclusive (Q13618)
KLHL24	KLHL42	0.983		mutually_exclusive (Q13618)
BTBD10	KLHL18	0.983	0.119	mutually_exclusive (Q13618)
KLHL24	KLHL18	0.983		mutually_exclusive (Q13618)
KCTD20	KLHL18	0.983	0.084	mutually_exclusive (Q13618)
ANKRD39	COPS5	0.983	0.118
COPS9	LRR1	0.983	0.09
BTBD10	CUL3	0.982	0.166	structurally_consistent (dimer)
COPS9	FEM1B	0.981	0.1	structurally_consistent (Q9UNS2)
KCTD20	BTBD2	0.981	0.106	mutually_exclusive (Q13618)
BTBD10	BTBD2	0.981	0.078	mutually_exclusive (Q13618)
KLHL24	KCTD20	0.981		mutually_exclusive (Q13618)
DCAF16	DCAF6	0.98	0.054
COPS9	ERCC8	0.979	0.17
LRR1	DCAF11	0.979	0.106
KLHL42	BTBD2	0.979	0.174	mutually_exclusive (Q13618)
CUL2	DDB2	0.978	0.118
BTBD1	FEM1B	0.977	0.158
BTBD1	APPBP2	0.977	0.114
COPS9	DDB2	0.977	0.068
FEM1B	COPS5	0.975	0.182
KLHL13	BTBD10	0.975	0.104	mutually_exclusive (Q13618)
KCTD20	KLHL42	0.975	0.11	mutually_exclusive (Q13618)
FEM1B	APPBP2	0.973	0.186
DCAF16	GPS1	0.973	0.246
ERCC8	DCAF4	0.973	0.112	mutually_exclusive (Q16531)
KLHL18	KLHL42	0.972	0.092	mutually_exclusive (Q13618)
APPBP2	COPS4	0.972	0.09
FEM1B	DCAF4	0.972	0.09
ERCC8	COPS5	0.971	0.346
LRR1	APPBP2	0.971	0.096
BTBD2	APPBP2	0.97	0.15
KLHL18	CUL3	0.969	0.278	structurally_consistent (dimer)
ERCC8	DCAF11	0.969	0.108	mutually_exclusive (Q16531)
ERCC8	COPS4	0.968	0.154	mutually_exclusive (Q99627)
DCAF16	DCAF11	0.966	0.074
ERCC8	DDB2	0.966	0.09	mutually_exclusive (Q16531)
KLHL18	COPS4	0.965	0.13	mutually_exclusive (Q13618)
DCAF11	APPBP2	0.962	0.068
KLHL13	KCTD20	0.961	0.168	mutually_exclusive (Q13618)
CUL3	ANKRD39	0.961	0.268
FEM1B	DCAF11	0.96	0.08
DCAF4	BTBD2	0.96	0.068
KCTD20	COPS5	0.959	0.156
FEM1B	DDB2	0.959	0.08
APPBP2	DDB2	0.958	0.142
COPS5	APPBP2	0.955	0.108
KLHL18	COPS9	0.955	0.098
COPS9	DCAF4	0.951	0.102
KLHL13	KLHL18	0.951	0.142	mutually_exclusive (Q13618)
LRR1	FBXO17	0.95	0.072
DCAF4	APPBP2	0.944	0.104
KLHL18	BTBD2	0.944	0.098	mutually_exclusive (Q13618)
DCAF6	DCAF11	0.938	0.06	mutually_exclusive (Q16531) structurally_consistent (dimer)
FEM1B	BTBD2	0.936	0.154
DCAF4	FBXO17	0.935	0.094
KLHL13	COPS4	0.935	0.184	mutually_exclusive (Q13618)
COPS9	FBXO17	0.93	0.098
DCAF11	FBXO17	0.929	0.094
DCAF16	COPS4	0.926	0.34
FBXO17	DDB2	0.923	0.098
ANKRD39	FBXO17	0.921	0.08	structurally_consistent (dimer)
FEM1B	FBXO17	0.917	0.092
DCAF6	DDB2	0.916	0.09	mutually_exclusive (Q16531)
CUL2	FBXO17	0.912	0.106
DCAF16	DDB2	0.911	0.062
KLHL18	BTBD1	0.911	0.12	mutually_exclusive (Q13618)
DCAF6	COPS5	0.91	0.174
KLHL42	ANKRD39	0.91	0.122	structurally_consistent (Q96EF6)
FBXO17	APPBP2	0.904	0.098
DCAF6	FBXO17	0.902	0.062
KLHL24	KLHL13	0.894		mutually_exclusive (Q13618)
KLHL24	BTBD2	0.89		mutually_exclusive (Q13618)
BTBD10	COPS5	0.89	0.124
DCAF6	APPBP2	0.889	0.112
CUL2	DCAF11	0.887	0.086
BTBD1	FBXO17	0.885	0.078
FEM1C	FEM1B	0.884
KLHL13	BTBD2	0.878	0.108	mutually_exclusive (Q13618)
KLHL24	BTBD1	0.871		mutually_exclusive (Q13618)
KLHL24	GPS1	0.862
KLHL24	COPS4	0.854		mutually_exclusive (Q13618)
BTBD2	FBXO17	0.852	0.06
ANKRD39	DDB2	0.851	0.192
KLHL13	KLHL42	0.847	0.088	mutually_exclusive (Q13618)
KLHL42	COPS4	0.84	0.214
CUL2	DCAF6	0.821	0.2
ERCC8	FEM1B	0.815	0.094
CUL2	ERCC8	0.815	0.136
KLHL24	ANKRD39	0.812
ERCC8	APPBP2	0.81	0.084
KLHL13	BTBD1	0.805	0.112	mutually_exclusive (Q13618)
ERCC8	LRR1	0.8	0.074
BTBD2	DCAF11	0.797	0.13
BTBD1	ERCC8	0.781	0.096
DCAF6	ERCC8	0.764	0.084	mutually_exclusive (Q16531)
CUL3	ERCC8	0.736	0.144
KLHL18	COPS5	0.735	0.2984
CUL3	LRR1	0.732	0.248
ANKRD39	BTBD2	0.73	0.136
FEM1C	APPBP2	0.725
ERCC8	BTBD2	0.725	0.154
KLHL18	DDB2	0.723	0.064
DCAF6	COPS4	0.699	0.152	structurally_consistent (Q13098)
KLHL18	FEM1B	0.684	0.178
CUL2	ANKRD39	0.666	0.108	mutually_exclusive (P61201)
KLHL18	LRR1	0.656	0.092
KLHL18	CUL2	0.654	0.118
KLHL13	COPS9	0.646	0.078
KLHL18	DCAF11	0.637	0.088
CUL3	FBXO17	0.612	0.19	structurally_consistent (Q9P2K6)
KLHL18	APPBP2	0.594	0.118
KLHL42	DCAF11	0.582	0.08
FEM1C	DCAF4	0.565
KLHL13	APPBP2	0.563	0.11
FEM1C	LRR1	0.553
KLHL18	DCAF4	0.532	0.166
CUL3	DCAF4	0.525	0.232326300985
DCAF6	LRR1	0.522	0.076
DCAF6	DCAF4	0.508	0.1	mutually_exclusive (Q16531)
DCAF16	COPS5	0.504	0.512
KLHL18	ERCC8	0.48	0.124
ERCC8	FBXO17	0.47	0.124
KLHL18	FBXO17	0.468	0.1
KLHL42	FEM1C	0.465
KLHL13	COPS5	0.447	0.314
DCAF16	ANKRD39	0.444	0.124
FEM1C	COPS4	0.436
DCAF16	ERCC8	0.435	0.084
KLHL13	LRR1	0.434	0.142
KLHL18	FEM1C	0.431
FEM1C	COPS5	0.414
KLHL13	DCAF4	0.404	0.096
FEM1C	COPS9	0.401
ERCC8	ANKRD39	0.389	0.098	mutually_exclusive (Q99627)
DCAF6	BTBD2	0.345	0.098
BTBD10	ANKRD39	0.333	0.15
COPS9	DCAF6	0.311	0.078
KLHL24	FBXO17	0.31
KLHL42	APPBP2	0.289	0.174
FEM1C	DCAF11	0.283
DCAF6	FEM1B	0.282	0.14
CUL3	APPBP2	0.26	0.381215189873
KLHL18	DCAF6	0.251	0.086
FEM1C	BTBD1	0.244
FEM1C	DCAF6	0.239
FEM1C	DDB2	0.234
DCAF6	BTBD1	0.233	0.108
KCTD20	LRR1	0.232	0.106
BTBD10	LRR1	0.232	0.112
BTBD10	DDB2	0.232	0.076
BTBD10	CUL2	0.232	0.096
KCTD20	CUL2	0.232	0.146
BTBD10	DCAF11	0.232	0.068
CUL3	DDB2	0.231	0.256
KLHL24	COPS5	0.23
KLHL13	DCAF11	0.225	0.072
KLHL42	DDB2	0.222	0.052
KLHL24	CUL2	0.217
KLHL18	ANKRD39	0.213	0.176
KLHL24	DCAF11	0.206
CUL3	FEM1B	0.201	0.246
KLHL42	FEM1B	0.198	0.136
KCTD20	DCAF11	0.192	0.134
KCTD20	DCAF4	0.192	0.072
KCTD20	DDB2	0.192	0.13
BTBD10	DCAF4	0.192	0.054
KLHL42	COPS5	0.179	0.3
KCTD20	ANKRD39	0.172	0.176
CUL3	CUL2	0.17	0.54
KLHL42	DCAF6	0.168	0.094
KLHL42	CUL2	0.167	0.148
KLHL13	DDB2	0.166	0.088
DCAF16	FEM1C	0.165
KLHL13	FEM1B	0.162	0.158
KLHL13	FEM1C	0.152
ANKRD39	DCAF11	0.151	0.09
BTBD1	ANKRD39	0.146	0.114	structurally_consistent (Q9UNS2)
CUL3	DCAF6	0.138	0.242
KLHL13	ANKRD39	0.135	0.116
KLHL13	CUL2	0.134	0.11
KLHL42	COPS9	0.129	0.068
CUL3	FEM1C	0.123
KLHL24	DDB2	0.123
KLHL42	LRR1	0.119	0.106
KLHL24	FEM1B	0.114
DCAF16	DCAF4	0.114	0.076
FEM1C	ANKRD39	0.113
KLHL24	COPS9	0.107
KLHL42	DCAF4	0.107	0.09
ANKRD39	DCAF4	0.102	0.12
FEM1C	BTBD2	0.101
KLHL24	LRR1	0.1
KLHL42	DCAF16	0.099	0.138
DCAF16	APPBP2	0.097	0.086
KLHL13	FBXO17	0.088	0.078
KLHL24	DCAF4	0.087
KLHL13	ERCC8	0.08	0.086
KLHL42	FBXO17	0.079	0.07	structurally_consistent (dimer)
FEM1C	FBXO17	0.078
ANKRD39	LRR1	0.076	0.12
FEM1C	ERCC8	0.076
KLHL24	APPBP2	0.071
ANKRD39	FEM1B	0.064	0.164
KLHL24	FEM1C	0.063
ANKRD39	APPBP2	0.062	0.154
KLHL24	DCAF16	0.061
DCAF16	FEM1B	0.055	0.1
DCAF16	CUL2	0.055	0.15
KLHL18	DCAF16	0.054	0.104
CUL3	DCAF11	0.053	0.225715189873
DCAF16	FBXO17	0.053	0.066
KLHL13	DCAF6	0.052	0.132
KLHL42	ERCC8	0.049	0.13
CUL3	DCAF16	0.049	0.291215189873
DCAF16	BTBD2	0.046	0.176
DCAF6	ANKRD39	0.046	0.138
DCAF16	LRR1	0.044	0.142
KLHL24	ERCC8	0.044
DCAF16	BTBD1	0.035	0.106
KLHL13	DCAF16	0.033	0.1
DCAF16	COPS9	0.026	0.09
KLHL24	DCAF6	0.01

Related Complexes

Genename	Complexes
COPS5	huMAP3_05041.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
KLHL13	huMAP3_02073.1 huMAP3_07590.1 huMAP3_07744.1 huMAP3_08550.1 huMAP3_09489.1 huMAP3_09779.1 huMAP3_10939.1 huMAP3_13639.1 huMAP3_14528.1
LRR1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_13769.1 huMAP3_14528.1
GPS1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
DCAF4	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
BTBD2	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12609.1 huMAP3_14528.1
CUL2	huMAP3_03490.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12267.1 huMAP3_14528.1
FEM1C	huMAP3_03490.1 huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12267.1 huMAP3_13131.1 huMAP3_14528.1
DDB2	huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12003.1 huMAP3_14528.1 huMAP3_14584.1
FEM1B	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12267.1 huMAP3_14528.1
CUL3	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_12888.1 huMAP3_13639.1 huMAP3_14528.1
COPS4	huMAP3_05041.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
DCAF16	huMAP3_02953.1 huMAP3_03628.1 huMAP3_07590.1 huMAP3_08251.1 huMAP3_08550.1 huMAP3_09283.1 huMAP3_09779.1 huMAP3_10612.1 huMAP3_14528.1 huMAP3_14809.1
DCAF6	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09283.1 huMAP3_09779.1 huMAP3_10612.1 huMAP3_12773.1 huMAP3_14528.1
APPBP2	huMAP3_05041.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
ERCC8	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
ANKRD39	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
BTBD1	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
KLHL24	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
COPS9	huMAP3_03628.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
FBXO17	huMAP3_05041.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
KCTD20	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
BTBD10	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
KLHL18	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1
KLHL42	huMAP3_02073.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_13416.1 huMAP3_14528.1
DCAF11	huMAP3_03628.1 huMAP3_06836.1 huMAP3_07590.1 huMAP3_08550.1 huMAP3_09779.1 huMAP3_14528.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07590.1

Complex Portal: CPX-14427