hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07595.1
Complex Portal: CPX-16299
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SVIL | Supervillin (Archvillin) (p205/p250) | 5 | UniProt NCBI |
| TPM3 | Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0006466 | 0.00401900764101 | 1.0 | SVIL TPM3 | Ankle flexion contracture |
| HP:0034677 | 0.00435734246793 | 1.0 | SVIL TPM3 | Ankle contracture |
| HP:0034673 | 0.0110727761538 | 1.0 | SVIL TPM3 | Abnormal ankle morphology |
| HP:0002987 | 0.0119134869358 | 1.0 | SVIL TPM3 | Elbow flexion contracture |
| HP:0006380 | 0.0133830220427 | 1.0 | SVIL TPM3 | Knee flexion contracture |
| HP:0034671 | 0.0139947587499 | 1.0 | SVIL TPM3 | Knee contracture |
| HP:0034391 | 0.0146201655512 | 1.0 | SVIL TPM3 | Elbow contracture |
| HP:0003458 | 0.0190185183012 | 1.0 | SVIL TPM3 | EMG: myopathic abnormalities |
| HP:0008366 | 0.0231913144999 | 1.0 | SVIL TPM3 | Foot joint contracture |
| HP:0003546 | 0.026485807158 | 1.0 | SVIL TPM3 | Exercise intolerance |
| HP:0002996 | 0.030911500096 | 1.0 | SVIL TPM3 | Limited elbow movement |
| HP:0003028 | 0.0434708989742 | 1.0 | SVIL TPM3 | Abnormality of the ankle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TPM3 | SVIL | 0.997 | 0.046 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SVIL | huMAP3_07595.1 huMAP3_09068.1 |
| TPM3 | huMAP3_06153.1 huMAP3_07595.1 huMAP3_08088.1 huMAP3_09542.1 |