hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07614.1
Complex Portal: CPX-18525
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HDAC3 | Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45) | 5 | UniProt NCBI |
| ERF | ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2) | 5 | UniProt NCBI |
| ANKRD11 | Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1) | 5 | UniProt NCBI |
| ETV3 | ETS translocation variant 3 (ETS domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor) | 5 | UniProt NCBI |
| HELZ | Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5426 | 1.36501667663e-05 | 0.4 | ANKRD11 HDAC3 | ANCO1-HDAC3 complex |
| HPA:0490692 | 0.0217088069864 | 1.0 | ERF HELZ HDAC3 ETV3 ANKRD11 | smooth muscle; smooth muscle cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HELZ | HDAC3 | 0.994 | 0.196 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ERF | HELZ | 0.986 | 0.102 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ERF | ETV3 | 0.97 | 0.174 | bioplex_WMM bioplex3_WMM WMM_only | |
| ERF | HDAC3 | 0.969 | 0.41 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ETV3 | HELZ | 0.958 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| ANKRD11 | HDAC3 | 0.952 | 0.366 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ETV3 | HDAC3 | 0.926 | 0.436929133858 | bioplex_WMM bioplex3_WMM WMM_only | |
| ERF | ANKRD11 | 0.013 | 0.1 | bioplex3_WMM WMM_only | |
| ETV3 | ANKRD11 | 0.013 | 0.122 | bioplex3_WMM WMM_only | |
| ANKRD11 | HELZ | 0.004 | 0.112 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes