hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07618.1
Complex Portal: CPX-18552
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TXNL4A | Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD) | 5 | UniProt NCBI |
| NCDN | Neurochondrin | 5 | UniProt NCBI |
| ECD | Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1) | 5 | UniProt NCBI |
| TSSC4 | U5 small nuclear ribonucleoprotein TSSC4 (Tumor-suppressing STF cDNA 4 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) | 5 | UniProt NCBI |
| EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) | 5 | UniProt NCBI |
| ZNHIT2 | Zinc finger HIT domain-containing protein 2 (Protein FON) | 4 | UniProt NCBI |
| EAPP | E2F-associated phosphoprotein (EAPP) | 5 | UniProt NCBI |
| AAR2 | Protein AAR2 homolog (AAR2 splicing factor homolog) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0097525 | 0.00115498793492 | 0.5 | TXNL4A AAR2 EFTUD2 TSSC4 | spliceosomal snRNP complex |
| GO:0030532 | 0.00197464201845 | 0.5 | TXNL4A AAR2 EFTUD2 TSSC4 | small nuclear ribonucleoprotein complex |
| GO:0120114 | 0.00366371076373 | 0.5 | TXNL4A AAR2 EFTUD2 TSSC4 | Sm-like protein family complex |
| GO:0005682 | 0.0043754188034 | 0.375 | TXNL4A AAR2 TSSC4 | U5 snRNP |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EFTUD2 | TSSC4 | 1.0 | 0.196 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM | |
| EFTUD2 | AAR2 | 1.0 | 0.679 |
structurally_consistent (Q96DI7)
|
bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| EAPP | AAR2 | 1.0 | 0.11 |
structurally_consistent (Q6P2Q9)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction boldt_WMM |
| ECD | EAPP | 1.0 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| EFTUD2 | EAPP | 0.999 | 0.212 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 boldt_WMM | |
| ECD | TSSC4 | 0.999 | 0.078 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 | |
| EAPP | TSSC4 | 0.999 | 0.176 |
structurally_consistent (Q6P2Q9)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| ECD | AAR2 | 0.999 | 0.048 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM | |
| TXNL4A | TSSC4 | 0.999 | 0.284 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | |
| ECD | EFTUD2 | 0.999 | 0.273674178404 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| ZNHIT2 | TSSC4 | 0.999 | 0.104 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NCDN | ECD | 0.999 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| ECD | ZNHIT2 | 0.999 | 0.148 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NCDN | AAR2 | 0.999 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| AAR2 | TSSC4 | 0.998 | 0.246 |
structurally_consistent (Q6P2Q9)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 boldt_WMM |
| EAPP | TXNL4A | 0.997 | 0.13 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| NCDN | EAPP | 0.996 | 0.084 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| AAR2 | ZNHIT2 | 0.996 | 0.152 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| EAPP | ZNHIT2 | 0.995 | 0.088 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EFTUD2 | TXNL4A | 0.992 | 0.512 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| EFTUD2 | ZNHIT2 | 0.991 | 0.184 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| NCDN | TSSC4 | 0.991 | 0.124 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NCDN | EFTUD2 | 0.976 | 0.202 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| AAR2 | TXNL4A | 0.974 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| ZNHIT2 | TXNL4A | 0.95 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only | |
| NCDN | ZNHIT2 | 0.914 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| NCDN | TXNL4A | 0.75 | 0.014 | bioplex_WMM bioplex3_WMM WMM_only | |
| ECD | TXNL4A | 0.721 | 0.02 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes