hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07620.1

Complex Portal: CPX-19940

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
STRIP1	Striatin-interacting protein 1 (Protein FAM40A)	5	UniProt NCBI
STK26	Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)	5	UniProt NCBI
SLMAP	Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein)	5	UniProt NCBI
STRN4	Striatin-4 (Zinedin)	5	UniProt NCBI
CTTNBP2NL	CTTNBP2 N-terminal-like protein	5	UniProt NCBI
STK24	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	5	UniProt NCBI
STRN	Striatin	5	UniProt NCBI
MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)	5	UniProt NCBI
MINK1	Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)	5	UniProt NCBI
CTTNBP2	Cortactin-binding protein 2 (CortBP2)	5	UniProt NCBI
FGFR1OP2	FGFR1 oncogene partner 2	4	UniProt NCBI
PDCD10	Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15)	5	UniProt NCBI
TRAF3IP3	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3)	5	UniProt NCBI
MOB4	MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)	5	UniProt NCBI
SIKE1	Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0090443	0.000174830724535	0.2	STRN4 STRN PDCD10	FAR/SIN/STRIPAK complex
HPA:0100201	0.000684495073256	0.866666666667	STK26 SLMAP SIKE1 STRN4 CTTNBP2NL STRN CTTNBP2 MINK1 MOB4 TRAF3IP3 FGFR1OP2 PDCD10 STK24	cerebral cortex; endothelial cells[>=Low]
HPA:0500111	0.0046653805723	0.6	STRIP1 CTTNBP2 STK26 STRN4 CTTNBP2NL SIKE1 FGFR1OP2 PDCD10 STK24	soft tissue 1; chondrocytes[>=Low]
HPA:0490691	0.00480447623988	0.866666666667	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP FGFR1OP2 MOB4 TRAF3IP3 PDCD10 CTTNBP2	smooth muscle; smooth muscle cells[>=Low]
HPA:0490000	0.00480447623988	0.866666666667	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP FGFR1OP2 MOB4 TRAF3IP3 PDCD10 CTTNBP2	smooth muscle
HPA:0030051	0.00536677168989	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	appendix; glandular cells[>=Low]
HPA:0350471	0.00794493839038	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	pancreas; exocrine glandular cells[>=Low]
HPA:0130051	0.0081719366649	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	colon; glandular cells[>=Low]
HPA:0400051	0.00910169384623	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	rectum; glandular cells[>=Low]
HPA:0470000	0.00943931800014	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	skin 2
HPA:0480051	0.00945953213168	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	small intestine; glandular cells[>=Low]
HPA:0150051	0.00991443135118	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	duodenum; glandular cells[>=Low]
HPA:0480052	0.0168604553218	0.866666666667	STRIP1 STK24 STK26 STRN4 STRN SIKE1 CTTNBP2NL CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	small intestine; glandular cells[>=Medium]
HPA:0350000	0.0178617739596	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	pancreas
HPA:0100212	0.0182052003769	0.6	STRIP1 CTTNBP2 SIKE1 STRN4 STRN FGFR1OP2 TRAF3IP3 PDCD10 STK24	cerebral cortex; neuropil[>=Medium]
WP:WP4537	0.0184937836061	0.133333333333	MAP4K4 MINK1	Hippo YAP signaling
HPA:0400052	0.0185808131437	0.866666666667	STRIP1 STK24 STK26 STRN4 STRN SIKE1 CTTNBP2NL CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	rectum; glandular cells[>=Medium]
HPA:0550000	0.0232386256213	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	stomach 2
HPA:0550051	0.0232386256213	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	stomach 2; glandular cells[>=Low]
HPA:0540000	0.0251545804151	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	stomach 1
HPA:0540051	0.0251545804151	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	stomach 1; glandular cells[>=Low]
HPA:0330221	0.0259269183495	0.866666666667	STRIP1 STK24 STK26 STRN4 STRN SIKE1 CTTNBP2NL CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	oral mucosa; squamous epithelial cells[>=Low]
HPA:0330000	0.0259269183495	0.866666666667	STRIP1 STK24 STK26 STRN4 STRN SIKE1 CTTNBP2NL CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	oral mucosa
HPA:0220051	0.0265286040698	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	gallbladder; glandular cells[>=Low]
HPA:0220000	0.0265286040698	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	gallbladder
HPA:0600000	0.0313769038626	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	tonsil
HPA:0030000	0.0316823225532	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	appendix
HPA:0480000	0.0333791899346	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	small intestine
HPA:0150000	0.0348899297306	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	duodenum
HPA:0400000	0.0389820538583	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	rectum
HPA:0340000	0.0433911875072	0.8	SIKE1 MINK1 CTTNBP2NL STRN4 STRN SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 STK24	ovary
HPA:0220052	0.0472302375227	0.866666666667	STRIP1 STK24 STK26 STRN4 STRN SIKE1 CTTNBP2NL CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	gallbladder; glandular cells[>=Medium]
HPA:0100000	0.0472600971465	0.933333333333	STRIP1 STK24 STRN STK26 STRN4 CTTNBP2NL SIKE1 SLMAP CTTNBP2 FGFR1OP2 MOB4 TRAF3IP3 PDCD10 MINK1	cerebral cortex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
STK26	PDCD10	1.0	0.784
STRN	CTTNBP2NL	1.0	0.094
STRIP1	STRN	1.0	0.388	mutually_exclusive (Q9Y3A3)
STRN	MOB4	1.0	0.108	structurally_consistent (dimer)
SIKE1	STRN	1.0	0.122
SLMAP	STRN	1.0
STRN4	STRN	1.0	0.244	mutually_exclusive (Q9Y3A3) structurally_consistent (dimer)
STRIP1	SLMAP	1.0
STK24	PDCD10	1.0	0.19	mutually_exclusive (P62714)
STRN	FGFR1OP2	1.0	0.174
SLMAP	FGFR1OP2	1.0
STRIP1	STRN4	1.0	0.296
SIKE1	STRIP1	1.0	0.102
SIKE1	STRN4	1.0	0.148
SIKE1	MOB4	1.0	0.182
STRN4	MOB4	1.0	0.386	structurally_consistent (dimer)
SIKE1	FGFR1OP2	1.0	0.234
STRIP1	FGFR1OP2	1.0	0.134
SLMAP	STRN4	1.0
FGFR1OP2	MOB4	1.0	0.14
SIKE1	SLMAP	1.0
STRIP1	MOB4	1.0	0.138	structurally_consistent (dimer)
STRIP1	CTTNBP2NL	1.0	0.09
STRN4	FGFR1OP2	1.0	0.094
MOB4	PDCD10	1.0	0.26	structurally_consistent (P67775) structurally_consistent (dimer)
SIKE1	TRAF3IP3	0.999	0.176
FGFR1OP2	PDCD10	0.999	0.092
FGFR1OP2	TRAF3IP3	0.999	0.362
STRN4	CTTNBP2NL	0.999	0.152
STRN	PDCD10	0.999	0.082	mutually_exclusive (P62714)
STRIP1	PDCD10	0.999	0.072	mutually_exclusive (Q9Y3A3)
SLMAP	CTTNBP2NL	0.999
STK26	STK24	0.998	0.116	structurally_consistent (dimer)
STRN4	PDCD10	0.998	0.034
STRIP1	TRAF3IP3	0.998	0.138
TRAF3IP3	MOB4	0.998	0.076
STRN	CTTNBP2	0.998	0.05
STRN4	TRAF3IP3	0.998	0.054
PDCD10	CTTNBP2NL	0.998	0.02
MOB4	CTTNBP2NL	0.997	0.036
STRN	TRAF3IP3	0.997	0.132
SLMAP	PDCD10	0.997
FGFR1OP2	CTTNBP2NL	0.997	0.06
SIKE1	CTTNBP2NL	0.997	0.054
SLMAP	MOB4	0.997
SIKE1	PDCD10	0.996	0.154
STRN	STK26	0.996	0.104
STRIP1	CTTNBP2	0.994	0.034
STRN	MINK1	0.994	0.164
STRN	MAP4K4	0.992
MINK1	TRAF3IP3	0.99	0.132
MAP4K4	MINK1	0.988
FGFR1OP2	STK24	0.987	0.074
STRIP1	STK24	0.987	0.074
STRN4	STK26	0.986	0.078	mutually_exclusive (P67775)
STRIP1	MAP4K4	0.985
SLMAP	STK24	0.982
STRN4	STK24	0.982	0.074
FGFR1OP2	STK26	0.981	0.078
STK26	CTTNBP2NL	0.98	0.044
STK24	CTTNBP2NL	0.978	0.116
SIKE1	MAP4K4	0.977
SLMAP	STK26	0.977
STRN	STK24	0.973	0.12	mutually_exclusive (P62714)
MAP4K4	FGFR1OP2	0.971
CTTNBP2	CTTNBP2NL	0.968	0.064
SIKE1	CTTNBP2	0.968	0.054
SLMAP	MAP4K4	0.967
STRIP1	MINK1	0.963	0.164
SLMAP	CTTNBP2	0.96
CTTNBP2	FGFR1OP2	0.959	0.056
STRN4	CTTNBP2	0.959	0.092
STRN4	MINK1	0.959	0.186
MAP4K4	MOB4	0.956
STRIP1	STK26	0.955	0.078
MAP4K4	PDCD10	0.949
MINK1	MOB4	0.948	0.082
MAP4K4	CTTNBP2NL	0.941
STRN4	MAP4K4	0.932
CTTNBP2	MOB4	0.918	0.072
SIKE1	STK26	0.894	0.186
SIKE1	STK24	0.878	0.112
MINK1	FGFR1OP2	0.811	0.098
SIKE1	MINK1	0.811	0.102
MOB4	STK26	0.8	0.148	structurally_consistent (P67775)
MOB4	STK24	0.708	0.106
CTTNBP2	PDCD10	0.661	0.0766666666667
MAP4K4	STK24	0.62
TRAF3IP3	PDCD10	0.591	0.08
MAP4K4	STK26	0.497
MINK1	CTTNBP2NL	0.267	0.184
MINK1	CTTNBP2	0.231	0.112
MINK1	PDCD10	0.179	0.13
TRAF3IP3	STK26	0.16	0.026
SLMAP	MINK1	0.15
MAP4K4	CTTNBP2	0.13
MINK1	STK24	0.015	0.074
CTTNBP2	STK26	0.014	0.088
MINK1	STK26	0.014	0.102
CTTNBP2	STK24	0.014	0.094

Related Complexes

Genename	Complexes
STRIP1	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STK26	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
SLMAP	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_11869.1 huMAP3_13510.1
STRN4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
CTTNBP2NL	huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STK24	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
STRN	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
MAP4K4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
MINK1	huMAP3_00935.1 huMAP3_03716.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_09757.1 huMAP3_10333.1
CTTNBP2	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
FGFR1OP2	huMAP3_00935.1 huMAP3_03933.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
PDCD10	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
TRAF3IP3	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
MOB4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
SIKE1	huMAP3_00896.1 huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07620.1

Complex Portal: CPX-19940