hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07627.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS3 | Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A) | 5 | UniProt NCBI |
| INIP | SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1) | 5 | UniProt NCBI |
| NABP2 | SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070876 | 3.84480164306e-07 | 1.0 | INTS3 INIP NABP2 | SOSS complex |
| GO:0044818 | 0.00145910222354 | 1.0 | INTS3 INIP NABP2 | mitotic G2/M transition checkpoint |
| GO:0010972 | 0.00252170927764 | 1.0 | INTS3 INIP NABP2 | negative regulation of G2/M transition of mitotic cell cycle |
| GO:1902750 | 0.0028124724019 | 1.0 | INTS3 INIP NABP2 | negative regulation of cell cycle G2/M phase transition |
| GO:0035861 | 0.00675723888767 | 1.0 | INTS3 INIP NABP2 | site of double-strand break |
| GO:0010389 | 0.00820096190464 | 1.0 | INTS3 INIP NABP2 | regulation of G2/M transition of mitotic cell cycle |
| GO:0010212 | 0.00949377645712 | 1.0 | INTS3 INIP NABP2 | response to ionizing radiation |
| HPA:0060852 | 0.0101525993711 | 1.0 | INTS3 INIP NABP2 | bronchus; ciliated cells (cell body)[>=Medium] |
| GO:1902749 | 0.0112921824257 | 1.0 | INTS3 INIP NABP2 | regulation of cell cycle G2/M phase transition |
| HPA:0210851 | 0.0138403406022 | 1.0 | INTS3 INIP NABP2 | fallopian tube; ciliated cells (cell body)[>=Low] |
| GO:0090734 | 0.0165038110528 | 1.0 | INTS3 INIP NABP2 | site of DNA damage |
| REAC:R-HSA-6807505 | 0.017372320015 | 0.666666666667 | INTS3 NABP2 | RNA polymerase II transcribes snRNA genes |
| GO:0000086 | 0.0201788647033 | 1.0 | INTS3 INIP NABP2 | G2/M transition of mitotic cell cycle |
| HPA:0060851 | 0.0243942396884 | 1.0 | INTS3 INIP NABP2 | bronchus; ciliated cells (cell body)[>=Low] |
| GO:0044839 | 0.0263194935275 | 1.0 | INTS3 INIP NABP2 | cell cycle G2/M phase transition |
| GO:0007093 | 0.0298091316188 | 1.0 | INTS3 INIP NABP2 | mitotic cell cycle checkpoint signaling |
| HPA:0380513 | 0.030835510288 | 1.0 | INTS3 INIP NABP2 | placenta; decidual cells[High] |
| GO:1901991 | 0.0468435252984 | 1.0 | INTS3 INIP NABP2 | negative regulation of mitotic cell cycle phase transition |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NABP2 | INTS3 | 1.0 | 0.33 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction |
| INIP | NABP2 | 1.0 | 0.282 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction |
| INIP | INTS3 | 0.999 | 0.396 | hein_WMM bioplex_WMM bioplex3_WMM Malo fraction |
Related Complexes