hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07635.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HNRNPAB | Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1) | 5 | UniProt NCBI |
| KHDRBS3 | KH domain-containing, RNA-binding, signal transduction-associated protein 3 (RNA-binding protein T-Star) (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein) | 5 | UniProt NCBI |
| SYNCRIP | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | 5 | UniProt NCBI |
| HNRNPR | Heterogeneous nuclear ribonucleoprotein R (hnRNP R) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0080133 | 0.00179344174456 | 1.0 | HNRNPAB HNRNPR KHDRBS3 SYNCRIP | caudate; neuronal cells[High] |
| GO:0003729 | 0.00613433997379 | 1.0 | HNRNPAB HNRNPR KHDRBS3 SYNCRIP | mRNA binding |
| HPA:0100133 | 0.0134599376677 | 1.0 | HNRNPAB HNRNPR KHDRBS3 SYNCRIP | cerebral cortex; neuronal cells[High] |
| CORUM:1181 | 0.0148970606176 | 0.5 | SYNCRIP HNRNPR | C complex spliceosome |
| WP:WP411 | 0.0186440023495 | 0.5 | HNRNPAB HNRNPR | mRNA processing |
| HPA:0090183 | 0.0296286402726 | 0.75 | HNRNPAB KHDRBS3 HNRNPR | cerebellum; cells in granular layer[High] |
| HPA:0100123 | 0.0296286402726 | 0.75 | HNRNPAB HNRNPR SYNCRIP | cerebral cortex; glial cells[High] |
| HPA:0080122 | 0.0312387757321 | 1.0 | HNRNPAB HNRNPR KHDRBS3 SYNCRIP | caudate; glial cells[>=Medium] |
| GO:2000623 | 0.042122686785 | 0.5 | HNRNPAB SYNCRIP | negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SYNCRIP | HNRNPR | 0.998 | 0.552 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| HNRNPR | HNRNPAB | 0.98 | 0.61 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| SYNCRIP | HNRNPAB | 0.979 | 0.528 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| KHDRBS3 | SYNCRIP | 0.969 | 0.108 | bioplex_WMM Guru bioplex3_WMM youn_WMM fraction treiber_WMM |
| KHDRBS3 | HNRNPR | 0.964 | 0.224469437653 | Guru bioplex3_WMM youn_WMM fraction treiber_WMM |
| KHDRBS3 | HNRNPAB | 0.006 | 0.228 | bioplex3_WMM youn_WMM WMM_only treiber_WMM |
Related Complexes