hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07639.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCO2 | Protein SCO2 homolog, mitochondrial | 5 | UniProt NCBI |
| ZFYVE19 | Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) | 5 | UniProt NCBI |
| VPS4A | Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4) | 5 | UniProt NCBI |
| TRMT2A | tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0044878 | 0.0168521501606 | 0.5 | ZFYVE19 VPS4A | mitotic cytokinesis checkpoint signaling |
| GO:0009838 | 0.042122686785 | 0.5 | ZFYVE19 VPS4A | abscission |
| GO:0032466 | 0.042122686785 | 0.5 | ZFYVE19 VPS4A | negative regulation of cytokinesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VPS4A | TRMT2A | 0.993 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| SCO2 | VPS4A | 0.985 | 0.018 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| ZFYVE19 | VPS4A | 0.982 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SCO2 | TRMT2A | 0.81 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| ZFYVE19 | TRMT2A | 0.013 | 0.048 | fraction |
| SCO2 | ZFYVE19 | 0.011 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes