hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07644.1

Complex Portal: CPX-23482

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
SLMAP	Sarcolemmal membrane-associated protein (Sarcolemmal-associated protein)	5	UniProt NCBI
CTTNBP2NL	CTTNBP2 N-terminal-like protein	5	UniProt NCBI
TRAF3IP3	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3)	5	UniProt NCBI
C4orf19	Uncharacterized protein C4orf19	2	UniProt NCBI
CTTNBP2	Cortactin-binding protein 2 (CortBP2)	5	UniProt NCBI
PDCD10	Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15)	5	UniProt NCBI
SIKE1	Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)	5	UniProt NCBI
STK26	Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)	5	UniProt NCBI
STRN3	Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)	5	UniProt NCBI
STK24	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]	5	UniProt NCBI
FGFR1OP2	FGFR1 oncogene partner 2	4	UniProt NCBI
STRIP2	Striatin-interacting protein 2 (Protein FAM40B)	5	UniProt NCBI
STRIP1	Striatin-interacting protein 1 (Protein FAM40A)	5	UniProt NCBI
STRN4	Striatin-4 (Zinedin)	5	UniProt NCBI
STRN	Striatin	5	UniProt NCBI
MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)	5	UniProt NCBI
FILIP1	Filamin-A-interacting protein 1 (FILIP)	5	UniProt NCBI
MINK1	Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)	5	UniProt NCBI
MOB4	MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0090443	1.01987757791e-07	0.210526315789	PDCD10 STRN3 STRN STRN4	FAR/SIN/STRIPAK complex
GO:0051721	0.000889109827682	0.210526315789	STRN4 CTTNBP2NL STRN STRN3	protein phosphatase 2A binding
HPA:0490691	0.00122466014869	0.842105263158	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 FILIP1 STRIP1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP STK26	smooth muscle; smooth muscle cells[>=Low]
HPA:0490000	0.00122466014869	0.842105263158	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 FILIP1 STRIP1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP STK26	smooth muscle
HPA:0220000	0.00166206833556	0.947368421053	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 FILIP1 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	gallbladder
HPA:0220051	0.00166206833556	0.947368421053	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 FILIP1 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	gallbladder; glandular cells[>=Low]
HPA:0030051	0.00282596128403	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	appendix; glandular cells[>=Low]
HPA:0350471	0.00448236515838	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	pancreas; exocrine glandular cells[>=Low]
GO:0070016	0.00519447563198	0.157894736842	STRN4 STRN3 STRN	armadillo repeat domain binding
HPA:0470000	0.00548797983346	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	skin 2
HPA:0480051	0.00550177919272	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	small intestine; glandular cells[>=Low]
HPA:0150051	0.00581362415148	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	duodenum; glandular cells[>=Low]
HPA:0100201	0.00948793409718	0.736842105263	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 SLMAP MINK1 STK26	cerebral cortex; endothelial cells[>=Low]
HPA:0350000	0.0115900567219	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	pancreas
HPA:0570000	0.0135540256004	0.947368421053	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 FILIP1 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	testis
HPA:0550051	0.0157667399454	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	stomach 2; glandular cells[>=Low]
HPA:0550000	0.0157667399454	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	stomach 2
HPA:0540000	0.0172958825576	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	stomach 1
HPA:0540051	0.0172958825576	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	stomach 1; glandular cells[>=Low]
HPA:0600000	0.0223875176305	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	tonsil
HPA:0030000	0.0226419520055	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	appendix
HPA:0480000	0.0240626497003	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	small intestine
HPA:0150000	0.025337312772	0.894736842105	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 STRIP2 SLMAP C4orf19 STK26	duodenum
HPA:0420000	0.0328128084626	0.842105263158	FGFR1OP2 STK24 TRAF3IP3 STRN4 STRIP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 SLMAP C4orf19 STRN3	salivary gland
HPA:0420051	0.0328128084626	0.842105263158	FGFR1OP2 STK24 TRAF3IP3 STRN4 STRIP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 SLMAP C4orf19 STRN3	salivary gland; glandular cells[>=Low]
WP:WP4537	0.0338629884047	0.105263157895	MAP4K4 MINK1	Hippo YAP signaling
HPA:0100212	0.0365814358307	0.526315789474	FGFR1OP2 STRN3 STRN4 PDCD10 SIKE1 STK24 STRN STRIP1 CTTNBP2 TRAF3IP3	cerebral cortex; neuropil[>=Medium]
HPA:0130051	0.0378198097562	0.842105263158	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 SLMAP C4orf19 STK26	colon; glandular cells[>=Low]
HPA:0400051	0.0423550755761	0.842105263158	STRN3 STK24 TRAF3IP3 STRN4 FGFR1OP2 PDCD10 STRIP1 MINK1 MOB4 SIKE1 CTTNBP2NL STRN CTTNBP2 SLMAP C4orf19 STK26	rectum; glandular cells[>=Low]
CORUM:6720	0.0496196263904	0.0526315789474	FILIP1	FILIP1-FLNA complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
STK26	PDCD10	1.0	0.784
STRN	CTTNBP2NL	1.0	0.094
STRN3	CTTNBP2NL	1.0	0.056
STRIP1	STRN	1.0	0.388	mutually_exclusive (Q9Y3A3)
STRN	MOB4	1.0	0.108	structurally_consistent (dimer)
STRIP1	STRN3	1.0	0.11
SIKE1	STRN	1.0	0.122
SLMAP	STRN	1.0
STRN4	STRN	1.0	0.244	mutually_exclusive (Q9Y3A3) structurally_consistent (dimer)
MOB4	STRN3	1.0	0.238
SIKE1	STRN3	1.0	0.188
STRIP1	SLMAP	1.0
STK24	PDCD10	1.0	0.19	mutually_exclusive (P62714)
STRN	FGFR1OP2	1.0	0.174
SLMAP	STRN3	1.0
SLMAP	FGFR1OP2	1.0
STRIP1	STRN4	1.0	0.296
STRIP2	STRN3	1.0	0.122
SIKE1	STRIP1	1.0	0.102
SIKE1	STRN4	1.0	0.148
STRN	STRN3	1.0	0.136	mutually_exclusive (Q9NRL3)
SIKE1	MOB4	1.0	0.182
STRN4	MOB4	1.0	0.386	structurally_consistent (dimer)
SIKE1	FGFR1OP2	1.0	0.234
STRIP1	FGFR1OP2	1.0	0.134
SLMAP	STRN4	1.0
FGFR1OP2	MOB4	1.0	0.14
SIKE1	SLMAP	1.0
STRN4	STRN3	1.0	0.236	structurally_consistent (dimer)
STRIP2	STRN	1.0	0.102
STRIP1	MOB4	1.0	0.138	structurally_consistent (dimer)
FGFR1OP2	STRN3	1.0	0.172
STRIP1	CTTNBP2NL	1.0	0.09
STRN4	FGFR1OP2	1.0	0.094
STRIP2	STRIP1	1.0	0.102	mutually_exclusive (Q9Y3A3)
MOB4	PDCD10	1.0	0.26	structurally_consistent (P67775) structurally_consistent (dimer)
STRIP2	MOB4	1.0	0.092	structurally_consistent (dimer)
SIKE1	TRAF3IP3	0.999	0.176
FGFR1OP2	PDCD10	0.999	0.092
FGFR1OP2	TRAF3IP3	0.999	0.362
STRN4	CTTNBP2NL	0.999	0.152
STRIP2	SIKE1	0.999	0.076
STRN	PDCD10	0.999	0.082	mutually_exclusive (P62714)
STRIP2	FGFR1OP2	0.999	0.08
STRIP2	STRN4	0.999	0.126
STRIP1	PDCD10	0.999	0.072	mutually_exclusive (Q9Y3A3)
CTTNBP2	STRN3	0.999	0.116
SLMAP	CTTNBP2NL	0.999
STRIP2	TRAF3IP3	0.998
TRAF3IP3	STRN3	0.998	0.222
STK26	STK24	0.998	0.116	structurally_consistent (dimer)
STRN4	PDCD10	0.998	0.034
STRIP1	TRAF3IP3	0.998	0.138
C4orf19	PDCD10	0.998
TRAF3IP3	MOB4	0.998	0.076
PDCD10	STRN3	0.998	0.116
STRN	CTTNBP2	0.998	0.05
STRN4	TRAF3IP3	0.998	0.054
PDCD10	CTTNBP2NL	0.998	0.02
STRIP2	SLMAP	0.998
MOB4	CTTNBP2NL	0.997	0.036
STRN	TRAF3IP3	0.997	0.132
STRIP2	CTTNBP2NL	0.997	0.086
SLMAP	PDCD10	0.997
FGFR1OP2	CTTNBP2NL	0.997	0.06
SIKE1	CTTNBP2NL	0.997	0.054
SLMAP	MOB4	0.997
STRIP2	PDCD10	0.996	0.04	mutually_exclusive (Q9Y3A3)
SIKE1	PDCD10	0.996	0.154
STRN	STK26	0.996	0.104
C4orf19	STK24	0.996
C4orf19	STK26	0.996
STRIP1	CTTNBP2	0.994	0.034
MAP4K4	STRN3	0.994
STRN	MINK1	0.994	0.164
STRN	MAP4K4	0.992
STK26	STRN3	0.992	0.036
MINK1	TRAF3IP3	0.99	0.132
MAP4K4	MINK1	0.988
FGFR1OP2	STK24	0.987	0.074
STRIP1	STK24	0.987	0.074
STRN4	STK26	0.986	0.078	mutually_exclusive (P67775)
STRIP1	MAP4K4	0.985
SLMAP	STK24	0.982
STRN4	STK24	0.982	0.074
FGFR1OP2	STK26	0.981	0.078
MINK1	STRN3	0.98	0.082
STK26	CTTNBP2NL	0.98	0.044
STK24	CTTNBP2NL	0.978	0.116
SIKE1	MAP4K4	0.977
STK24	STRN3	0.977	0.048
SLMAP	STK26	0.977
STRN	STK24	0.973	0.12	mutually_exclusive (P62714)
STRIP2	MAP4K4	0.972
MAP4K4	FGFR1OP2	0.971
STRIP2	CTTNBP2	0.97	0.116
CTTNBP2	CTTNBP2NL	0.968	0.064
SIKE1	CTTNBP2	0.968	0.054
SLMAP	MAP4K4	0.967
STRIP1	MINK1	0.963	0.164
SLMAP	CTTNBP2	0.96
CTTNBP2	FGFR1OP2	0.959	0.056
STRN4	CTTNBP2	0.959	0.092
STRN4	MINK1	0.959	0.186
STRIP2	FILIP1	0.956	0.11
MAP4K4	MOB4	0.956
STRIP1	STK26	0.955	0.078
FILIP1	STRN3	0.951	0.092
MAP4K4	PDCD10	0.949
MINK1	MOB4	0.948	0.082
MAP4K4	CTTNBP2NL	0.941
STRN4	MAP4K4	0.932
STRIP2	STK26	0.931	0.048
CTTNBP2	MOB4	0.918	0.072
FILIP1	STRIP1	0.896	0.064
SIKE1	STK26	0.894	0.186
SIKE1	STK24	0.878	0.112
STRIP2	STK24	0.866	0.154
FILIP1	STRN4	0.822	0.04
MINK1	FGFR1OP2	0.811	0.098
STRIP2	MINK1	0.811	0.086
SIKE1	MINK1	0.811	0.102
MOB4	STK26	0.8	0.148	structurally_consistent (P67775)
FILIP1	MOB4	0.718	0.054
MOB4	STK24	0.708	0.106
FILIP1	STRN	0.694	0.086
FILIP1	PDCD10	0.688	0.088
CTTNBP2	PDCD10	0.661	0.0766666666667
MAP4K4	STK24	0.62
TRAF3IP3	PDCD10	0.591	0.08
MAP4K4	STK26	0.497
MINK1	CTTNBP2NL	0.267	0.184
MINK1	CTTNBP2	0.231	0.112
MINK1	PDCD10	0.179	0.13
TRAF3IP3	STK26	0.16	0.026
SLMAP	MINK1	0.15
MAP4K4	CTTNBP2	0.13
FILIP1	MAP4K4	0.071
FILIP1	STK26	0.019	0.048
MINK1	STK24	0.015	0.074
CTTNBP2	STK26	0.014	0.088
CTTNBP2	STK24	0.014	0.094
MINK1	STK26	0.014	0.102
FILIP1	CTTNBP2NL	0.012	0.082

Related Complexes

Genename	Complexes
SLMAP	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_11869.1 huMAP3_13510.1
CTTNBP2NL	huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
TRAF3IP3	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
C4orf19	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
CTTNBP2	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
PDCD10	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
SIKE1	huMAP3_00896.1 huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STK26	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
STRN3	huMAP3_05763.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STK24	huMAP3_01936.1 huMAP3_02705.1 huMAP3_02766.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10138.1 huMAP3_10333.1 huMAP3_11938.1 huMAP3_13510.1
FGFR1OP2	huMAP3_00935.1 huMAP3_03933.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STRIP2	huMAP3_00316.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STRIP1	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STRN4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
STRN	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
MAP4K4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
FILIP1	huMAP3_00316.1 huMAP3_05763.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1
MINK1	huMAP3_00935.1 huMAP3_03716.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_09757.1 huMAP3_10333.1
MOB4	huMAP3_00935.1 huMAP3_07620.1 huMAP3_07644.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_13510.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07644.1

Complex Portal: CPX-23482