hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07653.1

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
NDUFB7	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit)	5	UniProt NCBI
NDUFA6	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) (NADH-ubiquinone oxidoreductase B14 subunit)	5	UniProt NCBI
TRMT2B	tRNA (uracil-5-)-methyltransferase homolog B (EC 2.1.1.35) (TRM2 homolog B) (rRNA (uracil-5-)-methyltransferase TRMT2B) (EC 2.1.1.-)	5	UniProt NCBI
NDUFB8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)	5	UniProt NCBI
NDUFA10	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)	5	UniProt NCBI
NDUFS1	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD)	5	UniProt NCBI
NDUFA9	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Complex I-39kD) (CI-39kD) (NADH-ubiquinone oxidoreductase 39 kDa subunit)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:178	3.2873911248e-13	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Respiratory chain complex I (holoenzyme), mitochondrial
WP:WP623	2.10634049714e-12	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Oxidative phosphorylation
REAC:R-HSA-6799198	3.62993021232e-12	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Complex I biogenesis
WP:WP111	4.90947084117e-11	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Electron transport chain OXPHOS system in mitochondria
KEGG:04723	9.31412313794e-11	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Retrograde endocannabinoid signaling
GO:0008137	9.91594617915e-11	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NADH dehydrogenase (ubiquinone) activity
KEGG:00190	1.0847528036e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Oxidative phosphorylation
REAC:R-HSA-611105	1.11810009068e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Respiratory electron transport
GO:0050136	1.16151397783e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NADH dehydrogenase (quinone) activity
GO:0003954	1.35501997046e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NADH dehydrogenase activity
GO:0003955	1.82318372085e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NAD(P)H dehydrogenase (quinone) activity
GO:0006120	2.103549821e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial electron transport, NADH to ubiquinone
KEGG:04932	2.4073823255e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Non-alcoholic fatty liver disease
HP:0011923	2.53709896277e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Decreased activity of mitochondrial complex I
GO:0045271	3.61062217844e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	respiratory chain complex I
GO:0030964	3.61062217844e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NADH dehydrogenase complex
GO:0005747	3.61062217844e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial respiratory chain complex I
WP:WP4396	3.8243228151e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Nonalcoholic fatty liver disease
REAC:R-HSA-163200	3.83001432055e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
CORUM:2948	6.33740219902e-10	0.571428571429	NDUFA10 NDUFB8 NDUFA9 NDUFS1	Respiratory chain complex I (incomplete intermediate), mitochondrial
GO:0016655	8.37990043589e-10	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0015453	1.04452075302e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidoreduction-driven active transmembrane transporter activity
WP:WP4324	1.18489123043e-09	0.714285714286	NDUFB7 NDUFS1 NDUFA10 NDUFB8 NDUFA6	Mitochondrial complex I assembly model OXPHOS system
KEGG:05415	1.24198456375e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Diabetic cardiomyopathy
GO:0010257	1.29181280378e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	NADH dehydrogenase complex assembly
GO:0032981	1.29181280378e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial respiratory chain complex I assembly
GO:0042776	1.7529090922e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	proton motive force-driven mitochondrial ATP synthesis
KEGG:05208	2.33826700981e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Chemical carcinogenesis - reactive oxygen species
HP:0008972	2.36249057929e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Decreased activity of mitochondrial respiratory chain
KEGG:04714	2.55689171887e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Thermogenesis
HP:0011922	2.85127002892e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormal activity of mitochondrial respiratory chain
REAC:R-HSA-1428517	2.93951819207e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	The citric acid (TCA) cycle and respiratory electron transport
GO:0015986	3.38123378566e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	proton motive force-driven ATP synthesis
GO:0016651	4.77614273165e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidoreductase activity, acting on NAD(P)H
GO:0019646	5.63577767821e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	aerobic electron transport chain
KEGG:05012	6.3136448984e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Parkinson disease
GO:0098803	7.16433362003e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	respiratory chain complex
KEGG:05020	7.52364288884e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Prion disease
GO:0006754	9.02363054154e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ATP biosynthetic process
GO:0042775	9.02363054154e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial ATP synthesis coupled electron transport
GO:0042773	9.02363054154e-09	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ATP synthesis coupled electron transport
GO:0009145	1.04737490183e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine nucleoside triphosphate biosynthetic process
GO:0009206	1.04737490183e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine ribonucleoside triphosphate biosynthetic process
GO:0005746	1.12685593968e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial respirasome
GO:0070469	1.12685593968e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	respirasome
KEGG:05016	1.38408549253e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Huntington disease
GO:0009201	1.49688838803e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribonucleoside triphosphate biosynthetic process
HP:0003287	1.58908818153e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormality of mitochondrial metabolism
GO:0022904	1.71681656462e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	respiratory electron transport chain
GO:0009142	1.83648616726e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleoside triphosphate biosynthetic process
GO:0033108	1.83648616726e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial respiratory chain complex assembly
GO:0009055	2.54425790718e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	electron transfer activity
GO:0022900	2.88469823397e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	electron transport chain
HP:0012103	3.46736782904e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormality of the mitochondrion
KEGG:05014	4.06653947287e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Amyotrophic lateral sclerosis
KEGG:05010	5.43712788902e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Alzheimer disease
GO:1990204	6.15430777352e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidoreductase complex
GO:0006119	8.47353478753e-08	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidative phosphorylation
GO:0015399	1.39386944178e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	primary active transmembrane transporter activity
KEGG:05022	1.77839932754e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Pathways of neurodegeneration - multiple diseases
GO:0098800	3.24442854958e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	inner mitochondrial membrane protein complex
GO:0009060	3.52298201497e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	aerobic respiration
GO:0009152	4.84471042999e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine ribonucleotide biosynthetic process
GO:0046034	6.55581495255e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ATP metabolic process
GO:0009260	6.80125518679e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribonucleotide biosynthetic process
GO:0045333	7.58395693553e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	cellular respiration
GO:0046390	8.44026861693e-07	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribose phosphate biosynthetic process
GO:0009205	1.00459135438e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine ribonucleoside triphosphate metabolic process
GO:0009144	1.07556444653e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine nucleoside triphosphate metabolic process
HP:0001941	1.1844013182e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Acidosis
GO:0009199	1.23008120552e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribonucleoside triphosphate metabolic process
GO:0006164	1.40265468265e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine nucleotide biosynthetic process
CORUM:2919	1.54229147311e-06	0.428571428571	NDUFA6 NDUFA9 NDUFA10	Respiratory chain complex I (gamma subunit) mitochondrial
GO:0009141	1.54492161377e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleoside triphosphate metabolic process
GO:0072522	1.64628435542e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine-containing compound biosynthetic process
HP:0004360	1.6975477969e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormality of acid-base homeostasis
GO:0009165	2.67500113646e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleotide biosynthetic process
GO:1901293	3.00232306247e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleoside phosphate biosynthetic process
GO:0015980	4.07877202556e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	energy derivation by oxidation of organic compounds
GO:1902495	7.03155441234e-06	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	transmembrane transporter complex
GO:1990351	1.13206439429e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	transporter complex
HP:0011017	1.3310926319e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormal cellular physiology
GO:0022804	1.4171153104e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	active transmembrane transporter activity
HP:0025354	1.75114847661e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormal cellular phenotype
GO:0098798	1.79728096133e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial protein-containing complex
GO:0009150	3.22485448348e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine ribonucleotide metabolic process
GO:0009259	3.89574481501e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribonucleotide metabolic process
GO:0019693	4.8503219619e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	ribose phosphate metabolic process
GO:0006091	4.8503219619e-05	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	generation of precursor metabolites and energy
HP:0002490	5.32614804607e-05	0.571428571429	NDUFA6 NDUFS1 NDUFB8 NDUFA10	Increased CSF lactate
HP:0030085	5.32614804607e-05	0.571428571429	NDUFA6 NDUFS1 NDUFB8 NDUFA10	Abnormal CSF lactate concentration
GO:0006163	0.000103377879561	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine nucleotide metabolic process
GO:0007005	0.000113567704922	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrion organization
GO:0005743	0.000124579730605	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial inner membrane
GO:0072521	0.000132403480467	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	purine-containing compound metabolic process
KEGG:01100	0.000163213797031	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Metabolic pathways
GO:0019866	0.000175378698208	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	organelle inner membrane
GO:0009117	0.000180508609016	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleotide metabolic process
HP:0025454	0.000190360293174	0.571428571429	NDUFA6 NDUFS1 NDUFB8 NDUFA10	Abnormal CSF metabolite concentration
GO:0006753	0.000196653257665	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleoside phosphate metabolic process
GO:0090407	0.000216989356502	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	organophosphate biosynthetic process
HP:0001942	0.000233978474571	0.571428571429	NDUFA6 NDUFB8 NDUFA9 NDUFS1	Metabolic acidosis
GO:0055086	0.000404027118061	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	nucleobase-containing small molecule metabolic process
CORUM:2884	0.000430566012817	0.285714285714	NDUFA6 NDUFA9	Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial
GO:1901137	0.000463144847377	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	carbohydrate derivative biosynthetic process
HP:0003128	0.000599578997833	0.571428571429	NDUFB7 NDUFA10 NDUFS1 NDUFA6	Lactic acidosis
GO:0016491	0.000868117651073	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	oxidoreductase activity
HP:0002151	0.000901685119147	0.571428571429	NDUFA6 NDUFB8 NDUFA9 NDUFS1	Increased serum lactate
CORUM:2904	0.000922010129722	0.285714285714	NDUFA6 NDUFA9	Respiratory chain complex I (intermediate VII/650kD), mitochondrial
GO:0031966	0.000937400669885	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial membrane
CORUM:2905	0.00112664416828	0.285714285714	NDUFA6 NDUFA9	Respiratory chain complex I (intermediate), mitochondrial
HP:0002093	0.00114187559468	0.714285714286	NDUFA6 NDUFS1 NDUFB8 NDUFA9 NDUFA10	Respiratory insufficiency
GO:0005740	0.00138469520969	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrial envelope
HP:0025116	0.00173964073645	0.428571428571	NDUFA6 NDUFS1 NDUFA10	Fetal distress
GO:0005739	0.00195755801633	1.0	TRMT2B NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	mitochondrion
CORUM:2914	0.00245532971616	0.285714285714	NDUFB7 NDUFB8	Respiratory chain complex I (beta subunit) mitochondrial
HP:0001639	0.00249705480857	0.571428571429	NDUFB7 NDUFA10 NDUFS1 NDUFA6	Hypertrophic cardiomyopathy
GO:0022857	0.00370746489181	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	transmembrane transporter activity
REAC:R-HSA-1430728	0.00383440417299	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Metabolism
HP:0012337	0.00510926273075	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	Abnormal homeostasis
GO:0019637	0.00544685045135	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	organophosphate metabolic process
GO:0005215	0.00729549474285	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	transporter activity
GO:1901135	0.00818025750972	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	carbohydrate derivative metabolic process
GO:0031967	0.0205605899593	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	organelle envelope
GO:0031975	0.0205605899593	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	envelope
GO:0098796	0.0206938362537	0.857142857143	NDUFA10 NDUFB7 NDUFS1 NDUFA9 NDUFA6 NDUFB8	membrane protein complex
HP:0001638	0.0333457044045	0.571428571429	NDUFB7 NDUFA10 NDUFS1 NDUFA6	Cardiomyopathy
HP:0032653	0.0348446257606	0.285714285714	NDUFA10 NDUFA9	Elevated lactate:pyruvate ratio
HP:0001637	0.0399728132931	0.571428571429	NDUFB7 NDUFA10 NDUFS1 NDUFA6	Abnormal myocardium morphology
HP:0002921	0.0451244081745	0.571428571429	NDUFA6 NDUFS1 NDUFB8 NDUFA10	Abnormal cerebrospinal fluid morphology
HP:0001511	0.0478764522021	0.571428571429	NDUFB7 NDUFA10 NDUFS1 NDUFA6	Intrauterine growth retardation

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
NDUFA6	NDUFA9	0.999	0.95	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
NDUFS1	NDUFB7	0.999	0.956	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only
NDUFS1	NDUFA9	0.999	0.956	hein_WMM bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM
NDUFB8	NDUFB7	0.999	0.984	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM fraction
NDUFA10	NDUFB7	0.998	0.896	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM fraction
NDUFB7	NDUFA9	0.998	0.974	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
NDUFB8	NDUFA6	0.998	0.89	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM fraction
NDUFB8	NDUFA9	0.997	0.968	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only
NDUFA6	NDUFS1	0.997	0.938	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
NDUFB8	NDUFS1	0.997	0.868	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only
NDUFA6	NDUFB7	0.997	0.868	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only
NDUFA10	NDUFS1	0.996	0.944	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM
NDUFA10	NDUFB8	0.995	0.872	hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
NDUFA10	NDUFA9	0.994	0.968	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM
NDUFA10	NDUFA6	0.988	0.874	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM
TRMT2B	NDUFB8	0.967	0.024	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
TRMT2B	NDUFS1	0.878	0.082	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
NDUFA10	TRMT2B	0.52	0.086	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
TRMT2B	NDUFA6	0.171	0.036	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
TRMT2B	NDUFB7	0.104	0.06	bioplex_WMM bioplex3_WMM fraction
TRMT2B	NDUFA9	0.08	0.084	bioplex_WMM bioplex3_WMM youn_WMM WMM_only

Related Complexes

Genename	Complexes
NDUFB7	huMAP3_02819.1 huMAP3_06397.1 huMAP3_07653.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_14018.1 huMAP3_14878.1
NDUFA6	huMAP3_02819.1 huMAP3_06397.1 huMAP3_07029.1 huMAP3_07653.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_14018.1 huMAP3_14878.1
TRMT2B	huMAP3_00412.1 huMAP3_03285.1 huMAP3_06686.1 huMAP3_07653.1 huMAP3_09175.1 huMAP3_09301.1 huMAP3_09567.1 huMAP3_09995.1 huMAP3_10871.1 huMAP3_14878.1
NDUFB8	huMAP3_01771.1 huMAP3_02819.1 huMAP3_06397.1 huMAP3_07069.1 huMAP3_07653.1 huMAP3_09175.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_14018.1 huMAP3_14878.1
NDUFA10	huMAP3_00149.1 huMAP3_02819.1 huMAP3_06397.1 huMAP3_07653.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_14018.1 huMAP3_14878.1
NDUFS1	huMAP3_02819.1 huMAP3_06397.1 huMAP3_07653.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_12412.1 huMAP3_14018.1 huMAP3_14878.1
NDUFA9	huMAP3_02819.1 huMAP3_06397.1 huMAP3_07653.1 huMAP3_09567.1 huMAP3_09982.1 huMAP3_14018.1 huMAP3_14878.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07653.1