hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07659.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRPF40A | Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6) | 5 | UniProt NCBI |
| ARGLU1 | Arginine and glutamate-rich protein 1 | 4 | UniProt NCBI |
| SRRM2 | Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) | 5 | UniProt NCBI |
| TRA2B | Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) | 5 | UniProt NCBI |
| SRSF11 | Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:351 | 5.34752441749e-06 | 0.8 | TRA2B SRSF11 PRPF40A SRRM2 | Spliceosome |
| REAC:R-HSA-72163 | 2.78873163091e-05 | 0.8 | TRA2B SRSF11 PRPF40A SRRM2 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 3.19999178813e-05 | 0.8 | TRA2B SRSF11 PRPF40A SRRM2 | mRNA Splicing |
| REAC:R-HSA-72203 | 9.66841881558e-05 | 0.8 | TRA2B SRSF11 PRPF40A SRRM2 | Processing of Capped Intron-Containing Pre-mRNA |
| CORUM:1261 | 0.000136445626745 | 0.4 | TRA2B SRRM2 | SRm160/300 complex |
| HPA:0080133 | 0.000138961892583 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | caudate; neuronal cells[High] |
| HPA:0620223 | 0.000154721380411 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | vagina; squamous epithelial cells[High] |
| HPA:0241103 | 0.000167056055969 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | heart muscle; cardiomyocytes[High] |
| HPA:0430053 | 0.000599444070561 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | seminal vesicle; glandular cells[High] |
| HPA:0090163 | 0.000703137369224 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | cerebellum; Purkinje cells[High] |
| HPA:0300202 | 0.00126149450383 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; endothelial cells[>=Medium] |
| HPA:0570733 | 0.00139614058698 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | testis; Leydig cells[High] |
| HPA:0461492 | 0.00161900343633 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; vascular mural cells[>=Medium] |
| HPA:0090183 | 0.00190850802923 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | cerebellum; cells in granular layer[High] |
| HPA:0100123 | 0.00190850802923 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | cerebral cortex; glial cells[High] |
| HPA:0350473 | 0.0022440506842 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | pancreas; exocrine glandular cells[High] |
| HPA:0610833 | 0.00276998008335 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | urinary bladder; urothelial cells[High] |
| HPA:0300201 | 0.00286519514017 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; endothelial cells[>=Low] |
| HPA:0470183 | 0.00339144619884 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 2; cells in granular layer[High] |
| HPA:0461491 | 0.00339144619884 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; vascular mural cells[>=Low] |
| HPA:0471413 | 0.00356842784326 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 2; cells in spinous layer[High] |
| REAC:R-HSA-8953854 | 0.00371793814615 | 0.8 | TRA2B SRSF11 PRPF40A SRRM2 | Metabolism of RNA |
| HPA:0570763 | 0.00400232454169 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | testis; pachytene spermatocytes[High] |
| HPA:0090193 | 0.00415999181714 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | cerebellum; cells in molecular layer[High] |
| HPA:0301362 | 0.00420012002292 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; alveolar cells type I[>=Medium] |
| HPA:0570793 | 0.0043222333229 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | testis; round or early spermatids[High] |
| HPA:0471463 | 0.00433732325393 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 2; langerhans cells[High] |
| HPA:0300203 | 0.0053835806112 | 0.6 | TRA2B SRRM2 SRSF11 | lung; endothelial cells[High] |
| HPA:0540053 | 0.00691444355796 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | stomach 1; glandular cells[High] |
| HPA:0630223 | 0.00758106556162 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | cervix; squamous epithelial cells[High] |
| HPA:0480053 | 0.00866174075521 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | small intestine; glandular cells[High] |
| HPA:0400053 | 0.00923771267384 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | rectum; glandular cells[High] |
| HPA:0301361 | 0.00937537502914 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; alveolar cells type I[>=Low] |
| HPA:0150053 | 0.00982321834532 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | duodenum; glandular cells[High] |
| HPA:0330223 | 0.011424797654 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | oral mucosa; squamous epithelial cells[High] |
| HPA:0340463 | 0.0117972006822 | 0.6 | TRA2B SRRM2 SRSF11 | ovary; ovarian stroma cells[High] |
| HPA:0090192 | 0.0133443376284 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | cerebellum; cells in molecular layer[>=Medium] |
| HPA:0600433 | 0.0141331186885 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | tonsil; germinal center cells[High] |
| HPA:0301372 | 0.0156796408588 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; alveolar cells type II[>=Medium] |
| HPA:0160253 | 0.0175907473609 | 0.6 | TRA2B SRRM2 SRSF11 | endometrium 1; cells in endometrial stroma[High] |
| HPA:0170053 | 0.0200286577533 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | endometrium 2; glandular cells[High] |
| HPA:0300413 | 0.0203515557622 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; macrophages[High] |
| HPA:0471473 | 0.0212982616684 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 2; lymphocytes[High] |
| HPA:0490692 | 0.0217088069864 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | smooth muscle; smooth muscle cells[>=Medium] |
| HPA:0050053 | 0.0219554107003 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | breast; glandular cells[High] |
| HPA:0570782 | 0.0222315456663 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | testis; preleptotene spermatocytes[>=Medium] |
| HPA:0570813 | 0.0224403274321 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | testis; spermatogonia cells[High] |
| HPA:0040083 | 0.0252885802715 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | bone marrow; hematopoietic cells[High] |
| HPA:0570772 | 0.026991266202 | 0.6 | TRA2B SRRM2 SRSF11 | testis; peritubular cells[>=Medium] |
| HPA:0301363 | 0.02767916363 | 0.6 | TRA2B SRRM2 SRSF11 | lung; alveolar cells type I[High] |
| HPA:0160053 | 0.0294062598088 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | endometrium 1; glandular cells[High] |
| HPA:0420053 | 0.029577214981 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | salivary gland; glandular cells[High] |
| HPA:0600223 | 0.0297489037729 | 0.8 | ARGLU1 SRSF11 PRPF40A TRA2B | tonsil; squamous epithelial cells[High] |
| HPA:0310432 | 0.0308725173414 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | lymph node; germinal center cells[>=Medium] |
| KEGG:03040 | 0.0346393491085 | 0.4 | TRA2B PRPF40A | Spliceosome |
| HPA:0130242 | 0.0355835654206 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | colon; peripheral nerve/ganglion[>=Medium] |
| HPA:0301371 | 0.0367361793849 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | lung; alveolar cells type II[>=Low] |
| HPA:0460182 | 0.0372666753661 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; cells in granular layer[>=Medium] |
| HPA:0470182 | 0.037477729829 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 2; cells in granular layer[>=Medium] |
| HPA:0170251 | 0.0422298811316 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | endometrium 2; cells in endometrial stroma[>=Low] |
| HPA:0461472 | 0.0423206374997 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; lymphocytes[>=Medium] |
| WP:WP411 | 0.0427057597692 | 0.4 | TRA2B PRPF40A | mRNA processing |
| HPA:0461462 | 0.0444139015161 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; langerhans cells[>=Medium] |
| HPA:0190223 | 0.0455701736828 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | esophagus; squamous epithelial cells[High] |
| HPA:0460202 | 0.0460879152407 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; endothelial cells[>=Medium] |
| HPA:0461412 | 0.0463303695681 | 0.6 | ARGLU1 SRRM2 TRA2B | skin 1; cells in spinous layer[>=Medium] |
| HPA:0490693 | 0.0465736551749 | 0.6 | TRA2B SRRM2 SRSF11 | smooth muscle; smooth muscle cells[High] |
| HPA:0210053 | 0.0468804820557 | 0.8 | ARGLU1 SRSF11 SRRM2 TRA2B | fallopian tube; glandular cells[High] |
| HPA:0351182 | 0.0492303149675 | 1.0 | ARGLU1 TRA2B PRPF40A SRSF11 SRRM2 | pancreas; pancreatic endocrine cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SRRM2 | ARGLU1 | 0.997 | 0.078 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| TRA2B | SRRM2 | 0.996 | 0.296 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| SRRM2 | PRPF40A | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM | |
| TRA2B | ARGLU1 | 0.991 | 0.59 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction treiber_WMM |
| SRSF11 | ARGLU1 | 0.958 | bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| SRSF11 | SRRM2 | 0.957 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| SRSF11 | TRA2B | 0.943 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction | |
| SRSF11 | PRPF40A | 0.779 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PRPF40A | ARGLU1 | 0.092 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TRA2B | PRPF40A | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes