hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07674.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCDC9 | Coiled-coil domain-containing protein 9 | 4 | UniProt NCBI |
| MAGOHB | Protein mago nashi homolog 2 | 5 | UniProt NCBI |
| EIF4A3 | Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] | 5 | UniProt NCBI |
| PNN | Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein) | 5 | UniProt NCBI |
| NKAPD1 | Uncharacterized protein NKAPD1 (NKAP domain containing protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035145 | 6.36865069892e-07 | 0.8 | PNN EIF4A3 CCDC9 MAGOHB | exon-exon junction complex |
| KEGG:03015 | 0.000112348611335 | 0.6 | PNN MAGOHB EIF4A3 | mRNA surveillance pathway |
| KEGG:03013 | 0.000153958097406 | 0.6 | PNN MAGOHB EIF4A3 | Nucleocytoplasmic transport |
| REAC:R-HSA-72163 | 0.00407681863898 | 0.6 | PNN MAGOHB EIF4A3 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.00451677062682 | 0.6 | PNN MAGOHB EIF4A3 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.0102904130445 | 0.6 | PNN MAGOHB EIF4A3 | Processing of Capped Intron-Containing Pre-mRNA |
| REAC:R-HSA-72187 | 0.0224106525753 | 0.4 | MAGOHB EIF4A3 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 0.0294410858888 | 0.4 | MAGOHB EIF4A3 | RNA Polymerase II Transcription Termination |
| KEGG:03040 | 0.0346393491085 | 0.4 | MAGOHB EIF4A3 | Spliceosome |
| REAC:R-HSA-159236 | 0.0363707033179 | 0.4 | MAGOHB EIF4A3 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| CORUM:1181 | 0.0395319616948 | 0.4 | PNN EIF4A3 | C complex spliceosome |
| REAC:R-HSA-72202 | 0.0463436196778 | 0.4 | MAGOHB EIF4A3 | Transport of Mature Transcript to Cytoplasm |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CCDC9 | EIF4A3 | 1.0 | 0.1 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () |
| PNN | CCDC9 | 0.999 | 0.158 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () |
| PNN | EIF4A3 | 0.996 | 0.896 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| EIF4A3 | NKAPD1 | 0.994 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CCDC9 | MAGOHB | 0.99 | 0.058 | hein_WMM bioplex3_WMM hein () |
| CCDC9 | NKAPD1 | 0.981 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PNN | MAGOHB | 0.97 | 0.766 | hein_WMM bioplex3_WMM WMM_only |
| PNN | NKAPD1 | 0.968 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MAGOHB | EIF4A3 | 0.869 | 0.84 | hein_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes