hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07678.1
Complex Portal: CPX-16826
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KIF18B | Kinesin-like protein KIF18B | 5 | UniProt NCBI |
| KIFBP | KIF-binding protein (KIF1-binding protein) (Kinesin family binding protein) | 5 | UniProt NCBI |
| KIF15 | Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62) | 5 | UniProt NCBI |
| KIF18A | Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983189 | 3.47141671819e-05 | 0.75 | KIF18B KIF18A KIF15 | Kinesins |
| REAC:R-HSA-6811434 | 0.000181248084935 | 0.75 | KIF18B KIF18A KIF15 | COPI-dependent Golgi-to-ER retrograde traffic |
| KEGG:04814 | 0.000236813619879 | 0.75 | KIF18B KIF18A KIF15 | Motor proteins |
| REAC:R-HSA-8856688 | 0.000453862022785 | 0.75 | KIF18B KIF18A KIF15 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-983231 | 0.000880808650283 | 0.75 | KIF18B KIF18A KIF15 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811442 | 0.00163910921321 | 0.75 | KIF18B KIF18A KIF15 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0005871 | 0.00298219742351 | 0.75 | KIF18B KIF18A KIF15 | kinesin complex |
| GO:0003777 | 0.00847564117007 | 0.75 | KIF18B KIF18A KIF15 | microtubule motor activity |
| REAC:R-HSA-109582 | 0.0327468558633 | 0.75 | KIF18B KIF18A KIF15 | Hemostasis |
| GO:0061673 | 0.042122686785 | 0.5 | KIF18B KIF18A | mitotic spindle astral microtubule |
| REAC:R-HSA-199991 | 0.0424877030349 | 0.75 | KIF18B KIF18A KIF15 | Membrane Trafficking |
| GO:0003774 | 0.0434703685672 | 0.75 | KIF18B KIF18A KIF15 | cytoskeletal motor activity |
| REAC:R-HSA-5653656 | 0.0499402458571 | 0.75 | KIF18B KIF18A KIF15 | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KIF18A | KIFBP | 1.0 | 0.084 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM |
| KIF15 | KIFBP | 0.995 | 0.054 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| KIF18B | KIFBP | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| KIF18A | KIF18B | 0.993 | hein_WMM bioplex_WMM bioplex3_WMM hein () | ||
| KIF18A | KIF15 | 0.764 | 0.224 |
mutually_exclusive (Q96EK5)
|
bioplex_WMM bioplex3_WMM WMM_only |
| KIF18B | KIF15 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes