hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07685.1
Complex Portal: CPX-16348
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDHB9 | Protocadherin beta-9 (PCDH-beta-9) (Protocadherin-3H) | 4 | UniProt NCBI |
| EPHX4 | Epoxide hydrolase 4 (EC 3.3.-.-) (Abhydrolase domain-containing protein 7) (Epoxide hydrolase-related protein) | 3 | UniProt NCBI |
| TMTC2 | Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 2) (Transmembrane and tetratricopeptide repeat-containing 2) | 5 | UniProt NCBI |
| PCDHB8 | Protocadherin beta-8 (PCDH-beta-8) (Protocadherin-3I) | 4 | UniProt NCBI |
| PCDHB2 | Protocadherin beta-2 (PCDH-beta-2) | 4 | UniProt NCBI |
| PCDHB3 | Protocadherin beta-3 (PCDH-beta-3) | 4 | UniProt NCBI |
| NUS1 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) | 5 | UniProt NCBI |
| B3GNT4 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4) | 5 | UniProt NCBI |
| PCDHB10 | Protocadherin beta-10 (PCDH-beta-10) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016339 | 0.000134592174076 | 0.444444444444 | PCDHB10 PCDHB9 PCDHB3 PCDHB2 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO:0007416 | 0.010739068416 | 0.444444444444 | PCDHB10 PCDHB9 PCDHB3 PCDHB2 | synapse assembly |
| GO:0098742 | 0.0272753050284 | 0.444444444444 | PCDHB10 PCDHB9 PCDHB3 PCDHB2 | cell-cell adhesion via plasma-membrane adhesion molecules |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDHB8 | PCDHB3 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB3 | PCDHB10 | 1.0 |
mutually_exclusive (Q9NRJ7)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB2 | PCDHB3 | 0.999 |
mutually_exclusive (Q9Y5G2)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PCDHB9 | PCDHB3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| B3GNT4 | PCDHB3 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMTC2 | PCDHB3 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHB3 | NUS1 | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| EPHX4 | PCDHB3 | 0.951 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDHB9 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB8 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB2 | PCDHB10 | 0.949 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB9 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB2 | PCDHB8 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| PCDHB2 | PCDHB9 | 0.946 |
mutually_exclusive (Q9Y5E6)
|
bioplex3_WMM WMM_only | |
| TMTC2 | PCDHB8 | 0.904 | 0.068 | bioplex3_WMM WMM_only | |
| TMTC2 | PCDHB9 | 0.904 | bioplex3_WMM WMM_only | ||
| B3GNT4 | PCDHB10 | 0.902 | bioplex3_WMM WMM_only | ||
| B3GNT4 | PCDHB9 | 0.902 | bioplex3_WMM WMM_only | ||
| B3GNT4 | PCDHB8 | 0.902 | bioplex3_WMM WMM_only | ||
| TMTC2 | PCDHB10 | 0.883 | bioplex3_WMM WMM_only | ||
| PCDHB2 | TMTC2 | 0.768 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHB2 | B3GNT4 | 0.73 | bioplex3_WMM WMM_only | ||
| PCDHB10 | NUS1 | 0.675 | bioplex3_WMM WMM_only | ||
| PCDHB9 | NUS1 | 0.675 | bioplex3_WMM WMM_only | ||
| PCDHB8 | NUS1 | 0.675 | 0.08 | bioplex3_WMM WMM_only | |
| EPHX4 | NUS1 | 0.579 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHB2 | NUS1 | 0.552 | bioplex3_WMM WMM_only | ||
| PCDHB2 | EPHX4 | 0.534 | bioplex_WMM bioplex3_WMM WMM_only | ||
| B3GNT4 | TMTC2 | 0.356 | bioplex3_WMM WMM_only | ||
| EPHX4 | PCDHB10 | 0.339 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TMTC2 | NUS1 | 0.261 | 0.084 | bioplex3_WMM WMM_only | |
| B3GNT4 | NUS1 | 0.254 | bioplex3_WMM WMM_only | ||
| EPHX4 | PCDHB8 | 0.249 | 0.074 | bioplex3_WMM WMM_only | |
| EPHX4 | PCDHB9 | 0.249 | bioplex3_WMM WMM_only | ||
| B3GNT4 | EPHX4 | 0.244 | bioplex3_WMM WMM_only | ||
| TMTC2 | EPHX4 | 0.152 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes