hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07697.1
Complex Portal: CPX-24214
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TIMP3 | Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3) | 5 | UniProt NCBI |
| GAS6 | Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-114608 | 0.00932983916662 | 1.0 | TIMP3 GAS6 | Platelet degranulation |
| REAC:R-HSA-76005 | 0.010244026704 | 1.0 | TIMP3 GAS6 | Response to elevated platelet cytosolic Ca2+ |
| REAC:R-HSA-76002 | 0.0400465404229 | 1.0 | TIMP3 GAS6 | Platelet activation, signaling and aggregation |
| HP:0030625 | 0.0499436884913 | 0.5 | TIMP3 | Hyporeflective spaces on macular OCT |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GAS6 | TIMP3 | 0.957 | 0.256 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes