hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07702.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SF3B2 | Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145) | 5 | UniProt NCBI |
| SMNDC1 | Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2755 | 0.000743311362176 | 1.0 | SF3B2 SMNDC1 | 17S U2 snRNP |
| KEGG:03040 | 0.00125991513217 | 1.0 | SF3B2 SMNDC1 | Spliceosome |
| CORUM:351 | 0.0159188244828 | 1.0 | SF3B2 SMNDC1 | Spliceosome |
| REAC:R-HSA-72163 | 0.0343461112178 | 1.0 | SF3B2 SMNDC1 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.0367862229998 | 1.0 | SF3B2 SMNDC1 | mRNA Splicing |
| HP:0004660 | 0.0499436884913 | 0.5 | SF3B2 | Hypoplasia of facial musculature |
| HP:0005439 | 0.0499436884913 | 0.5 | SF3B2 | Maxillozygomatic hypoplasia |
| HP:0008605 | 0.0499436884913 | 0.5 | SF3B2 | Unilateral external ear deformity |
| HP:0011270 | 0.0499436884913 | 0.5 | SF3B2 | Duplicated tragus |
| HP:0100731 | 0.0499436884913 | 0.5 | SF3B2 | Transverse facial cleft |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SMNDC1 | SF3B2 | 0.951 | 0.728 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SF3B2 | huMAP3_07702.1 |
| SMNDC1 | huMAP3_00782.1 huMAP3_07702.1 huMAP3_13766.1 |