hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07721.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLF2 | SMC5-SMC6 complex localization factor protein 2 (Smc5/6 localization factor 1) | 5 | UniProt NCBI |
| RAD18 | E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18) | 5 | UniProt NCBI |
| UBE2B | Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-110314 | 0.00296224002415 | 0.666666666667 | RAD18 UBE2B | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-73893 | 0.00735562020533 | 0.666666666667 | RAD18 UBE2B | DNA Damage Bypass |
| REAC:R-HSA-8866654 | 0.00973406489476 | 0.666666666667 | RAD18 UBE2B | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-8852135 | 0.0183561585619 | 0.666666666667 | RAD18 UBE2B | Protein ubiquitination |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLF2 | RAD18 | 0.998 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () | |
| RAD18 | UBE2B | 0.965 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes