hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07729.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SUSD4 | Sushi domain-containing protein 4 | 5 | UniProt NCBI |
| CYP24A1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24) | 5 | UniProt NCBI |
| MOCOS | Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (hMCS) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) | 5 | UniProt NCBI |
| HSD17B8 | (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579010 | 0.0499436884912 | 0.25 | CYP24A1 | Defective CYP24A1 causes HCAI |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MOCOS | HSD17B8 | 0.998 | 0.03 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SUSD4 | HSD17B8 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HSD17B8 | CYP24A1 | 0.958 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MOCOS | CYP24A1 | 0.041 | bioplex3_WMM WMM_only |
Related Complexes