hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07744.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| USP25 | Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) | 5 | UniProt NCBI |
| KLHL28 | Kelch-like protein 28 (BTB/POZ domain-containing protein 5) | 2 | UniProt NCBI |
| KLHL9 | Kelch-like protein 9 | 5 | UniProt NCBI |
| KLHL13 | Kelch-like protein 13 (BTB and kelch domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7523 | 3.07520988333e-05 | 0.5 | KLHL9 KLHL13 | Ubiquitin E3 ligase (CUL3, KLHL9, KLHL13, RBX1) |
| KEGG:04120 | 0.0224124539322 | 0.5 | KLHL9 KLHL13 | Ubiquitin mediated proteolysis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KLHL13 | KLHL28 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KLHL13 | KLHL9 | 0.998 | 0.19 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 bioplex_WMM WMM_only |
| KLHL9 | KLHL28 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| USP25 | KLHL9 | 0.977 | 0.2 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| KLHL13 | USP25 | 0.815 | 0.166 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| USP25 | KLHL28 | 0.343 | bioplex3_WMM WMM_only |
Related Complexes