hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07748.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RNGTT | mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)] | 5 | UniProt NCBI |
| SETX | Probable helicase senataxin (EC 3.6.4.-) (Amyotrophic lateral sclerosis 4 protein) (SEN1 homolog) (Senataxin) | 5 | UniProt NCBI |
| POLR2E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-77075 | 0.00221357222266 | 0.666666666667 | RNGTT POLR2E | RNA Pol II CTD phosphorylation and interaction with CE |
| REAC:R-HSA-167160 | 0.00221357222266 | 0.666666666667 | RNGTT POLR2E | RNA Pol II CTD phosphorylation and interaction with CE during HIV infection |
| REAC:R-HSA-72086 | 0.00257431960226 | 0.666666666667 | RNGTT POLR2E | mRNA Capping |
| REAC:R-HSA-167172 | 0.015485676782 | 0.666666666667 | RNGTT POLR2E | Transcription of the HIV genome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| POLR2E | SETX | 0.991 | 0.106 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| RNGTT | POLR2E | 0.957 | 0.162 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM |
| RNGTT | SETX | 0.044 | 0.052 | youn () bioplex3_WMM youn_WMM WMM_only |
Related Complexes