hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07751.1
Complex Portal: CPX-15402
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCDH19 | Protocadherin-19 | 5 | UniProt NCBI |
| CDH3 | Cadherin-3 (Placental cadherin) (P-cadherin) | 5 | UniProt NCBI |
| DCHS1 | Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) | 5 | UniProt NCBI |
| PCDH18 | Protocadherin-18 | 4 | UniProt NCBI |
| CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) | 5 | UniProt NCBI |
| PCDHGB1 | Protocadherin gamma-B1 (PCDH-gamma-B1) | 4 | UniProt NCBI |
| PCDH9 | Protocadherin-9 | 4 | UniProt NCBI |
| PCDHB2 | Protocadherin beta-2 (PCDH-beta-2) | 4 | UniProt NCBI |
| PCDH10 | Protocadherin-10 | 4 | UniProt NCBI |
| FAM171A1 | Protein FAM171A1 (Astroprincin) (APCN) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0007155 | 6.85594211552e-06 | 0.9 | PCDH9 PCDH10 DCHS1 CDH3 PCDHB2 CELSR3 PCDHGB1 PCDH19 PCDH18 | cell adhesion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCDH18 | PCDHGB1 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDH19 | PCDHGB1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | FAM171A1 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | PCDHB2 | 0.986 |
mutually_exclusive (Q9Y5G2)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CDH3 | PCDHGB1 | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | PCDH9 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DCHS1 | PCDHGB1 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PCDHGB1 | PCDH10 | 0.976 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCDHGB1 | CELSR3 | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DCHS1 | PCDH18 | 0.607 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH9 | CELSR3 | 0.46 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | CELSR3 | 0.451 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCDH19 | DCHS1 | 0.428 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | PCDH10 | 0.409 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PCDH18 | PCDH9 | 0.396 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDHB2 | 0.387 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH9 | PCDH10 | 0.354 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDH10 | 0.35 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDH18 | 0.35 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | PCDH9 | 0.341 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH18 | PCDH10 | 0.328 |
mutually_exclusive (Q9Y5G3)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| PCDH18 | CELSR3 | 0.328 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | CELSR3 | 0.304 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHB2 | CELSR3 | 0.283 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH18 | PCDHB2 | 0.265 |
mutually_exclusive (Q9Y5G3)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| DCHS1 | PCDHB2 | 0.265 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | FAM171A1 | 0.255 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCDH10 | FAM171A1 | 0.237 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | FAM171A1 | 0.231 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only | |
| CDH3 | PCDHB2 | 0.22 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH9 | PCDHB2 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDH10 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDHB2 | PCDH10 | 0.199 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | PCDH9 | 0.197 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | PCDH18 | 0.193 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH10 | CELSR3 | 0.176 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | DCHS1 | 0.173 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCDH9 | FAM171A1 | 0.171 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FAM171A1 | CELSR3 | 0.165 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| PCDHB2 | FAM171A1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH18 | FAM171A1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | FAM171A1 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| DCHS1 | PCDH9 | 0.161 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PCDH19 | CDH3 | 0.155 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CDH3 | CELSR3 | 0.129 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes