hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07757.1
Complex Portal: CPX-21086
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Protein SITPEC) | 5 | UniProt NCBI |
| ABCC10 | ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7) | 5 | UniProt NCBI |
| COA1 | Cytochrome c oxidase assembly factor 1 homolog (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa) | 4 | UniProt NCBI |
| SOD3 | Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4324 | 0.00377411060353 | 0.5 | COA1 ECSIT | Mitochondrial complex I assembly model OXPHOS system |
| REAC:R-HSA-6799198 | 0.0162811003561 | 0.5 | COA1 ECSIT | Complex I biogenesis |
| REAC:R-HSA-611105 | 0.0492961191682 | 0.5 | COA1 ECSIT | Respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ECSIT | COA1 | 0.995 | 0.286 |
mutually_exclusive (Q9Y375)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ECSIT | SOD3 | 0.989 | 0.05 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ECSIT | ABCC10 | 0.985 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ABCC10 | SOD3 | 0.715 | 0.062 | bioplex3_WMM WMM_only | |
| ABCC10 | COA1 | 0.107 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| SOD3 | COA1 | 0.046 | 0.04 | bioplex3_WMM WMM_only |
Related Complexes