hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07776.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CORO1A | Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO) | 5 | UniProt NCBI |
| CFL1 | Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform) | 5 | UniProt NCBI |
| CORO1B | Coronin-1B (Coronin-2) | 5 | UniProt NCBI |
| AFAP1 | Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) | 5 | UniProt NCBI |
| SYNPO | Synaptopodin | 5 | UniProt NCBI |
| DSTN | Destrin (Actin-depolymerizing factor) (ADF) | 5 | UniProt NCBI |
| CORO1C | Coronin-1C (Coronin-3) (hCRNN4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0015629 | 3.531185303e-07 | 1.0 | DSTN CORO1B SYNPO AFAP1 CORO1C CORO1A CFL1 | actin cytoskeleton |
| GO:0003779 | 1.48074113953e-05 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | actin binding |
| GO:0007015 | 4.93794774748e-05 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | actin filament organization |
| GO:0051015 | 0.00020083270634 | 0.714285714286 | CORO1A CORO1B DSTN CORO1C CFL1 | actin filament binding |
| GO:0030036 | 0.000759257961222 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | actin cytoskeleton organization |
| GO:0030029 | 0.00145686134313 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | actin filament-based process |
| GO:0097435 | 0.00165926194876 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | supramolecular fiber organization |
| GO:0008092 | 0.0043226725106 | 0.857142857143 | DSTN CORO1B SYNPO CORO1C CORO1A CFL1 | cytoskeletal protein binding |
| GO:0005856 | 0.00665123557963 | 1.0 | DSTN CORO1B SYNPO AFAP1 CORO1C CORO1A CFL1 | cytoskeleton |
| GO:0030027 | 0.00874901431253 | 0.571428571429 | CORO1A CORO1B CORO1C CFL1 | lamellipodium |
| GO:0030043 | 0.0294899169624 | 0.285714285714 | CFL1 DSTN | actin filament fragmentation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CORO1B | CORO1A | 0.999 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| CORO1B | CORO1C | 0.999 | 0.188 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| CORO1A | CORO1C | 0.998 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM |
| DSTN | AFAP1 | 0.993 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CFL1 | DSTN | 0.983 | 0.572 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| DSTN | CORO1C | 0.981 | 0.304 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| CFL1 | CORO1C | 0.965 | 0.184 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
| SYNPO | CORO1C | 0.963 | hein_WMM hein () | |
| CORO1C | AFAP1 | 0.963 | hein_WMM hein () | |
| CFL1 | AFAP1 | 0.952 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| SYNPO | DSTN | 0.781 | hein_WMM WMM_only | |
| CORO1B | AFAP1 | 0.773 | hein_WMM WMM_only | |
| SYNPO | AFAP1 | 0.773 | hein_WMM WMM_only | |
| CORO1B | SYNPO | 0.773 | hein_WMM WMM_only | |
| SYNPO | CFL1 | 0.764 | hein_WMM WMM_only | |
| CORO1B | DSTN | 0.758 | 0.19 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| CORO1B | CFL1 | 0.74 | 0.146 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| CORO1A | DSTN | 0.065 | 0.07 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CORO1A | CFL1 | 0.003 | 0.396 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
Related Complexes