hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07809.1
Complex Portal: CPX-17048
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STX19 | Syntaxin-19 | 5 | UniProt NCBI |
| STXBP2 | Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | 5 | UniProt NCBI |
| STXBP1 | Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0048278 | 0.00238416149886 | 1.0 | STXBP2 STX19 STXBP1 | vesicle docking |
| GO:0140029 | 0.00238416149886 | 1.0 | STXBP2 STX19 STXBP1 | exocytic process |
| GO:0140056 | 0.00481715197859 | 1.0 | STXBP2 STX19 STXBP1 | organelle localization by membrane tethering |
| GO:0022406 | 0.00703118100474 | 1.0 | STXBP2 STX19 STXBP1 | membrane docking |
| GO:0000149 | 0.00949377645712 | 1.0 | STXBP2 STX19 STXBP1 | SNARE binding |
| GO:0007269 | 0.00949377645712 | 1.0 | STXBP2 STX19 STXBP1 | neurotransmitter secretion |
| GO:0099643 | 0.00949377645712 | 1.0 | STXBP2 STX19 STXBP1 | signal release from synapse |
| WP:WP481 | 0.011426766529 | 0.666666666667 | STXBP2 STXBP1 | Insulin signaling |
| GO:0006836 | 0.019623483106 | 1.0 | STXBP2 STX19 STXBP1 | neurotransmitter transport |
| GO:0045055 | 0.0328130751425 | 1.0 | STXBP2 STX19 STXBP1 | regulated exocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| STX19 | STXBP2 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| STX19 | STXBP1 | 0.998 |
mutually_exclusive (P63027)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| STXBP2 | STXBP1 | 0.983 | 0.02 |
mutually_exclusive (O75558)
|
bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM |
Related Complexes