hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07820.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAGEA2 | Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen) | 5 | UniProt NCBI |
| KIF11 | Kinesin-like protein KIF11 (Kinesin-like protein 1) (Kinesin-like spindle protein HKSP) (Kinesin-related motor protein Eg5) (Thyroid receptor-interacting protein 5) (TR-interacting protein 5) (TRIP-5) | 5 | UniProt NCBI |
| CASKIN2 | Caskin-2 (CASK-interacting protein 2) | 3 | UniProt NCBI |
| PSD3 | PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) | 5 | UniProt NCBI |
| TSTD2 | Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (Rhodanese domain-containing protein 2) | 5 | UniProt NCBI |
| PDE4B | 3',5'-cyclic-AMP phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32) (cAMP-specific phosphodiesterase 4B) | 5 | UniProt NCBI |
| N4BP2 | NEDD4-binding protein 2 (N4BP2) (EC 3.-.-.-) (BCL-3-binding protein) | 5 | UniProt NCBI |
| UHRF2 | E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING finger protein 107) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2) | 5 | UniProt NCBI |
| NPAS1 | Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Basic-helix-loop-helix-PAS protein MOP5) (Class E basic helix-loop-helix protein 11) (bHLHe11) (Member of PAS protein 5) (PAS domain-containing protein 5) | 4 | UniProt NCBI |
| CASP2 | Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12] | 5 | UniProt NCBI |
| FAM98C | Protein FAM98C | 4 | UniProt NCBI |
| TOMM34 | Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit) | 5 | UniProt NCBI |
| ITPKC | Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase C) (IP3 3-kinase C) (IP3K C) (InsP 3-kinase C) | 5 | UniProt NCBI |
| ABR | Active breakpoint cluster region-related protein | 5 | UniProt NCBI |
| AKAP10 | A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:129 | 0.0499958217778 | 0.0714285714286 | CASP2 | PIDDsome complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| ABR | NPAS1 | 0.998 | |
| N4BP2 | NPAS1 | 0.998 | |
| AKAP10 | NPAS1 | 0.998 | |
| CASP2 | NPAS1 | 0.998 | |
| CASKIN2 | NPAS1 | 0.997 | |
| PDE4B | NPAS1 | 0.997 | |
| ITPKC | NPAS1 | 0.997 | |
| UHRF2 | NPAS1 | 0.996 | |
| FAM98C | NPAS1 | 0.996 | |
| PSD3 | NPAS1 | 0.995 | |
| MAGEA2 | NPAS1 | 0.994 | |
| TSTD2 | NPAS1 | 0.993 | |
| NPAS1 | TOMM34 | 0.971 | |
| KIF11 | NPAS1 | 0.959 | |
| AKAP10 | PSD3 | 0.775 | 0.09 |
| FAM98C | CASKIN2 | 0.73 | 0.138 |
| FAM98C | N4BP2 | 0.73 | 0.068 |
| CASKIN2 | TSTD2 | 0.73 | 0.09 |
| CASKIN2 | PDE4B | 0.73 | |
| TSTD2 | N4BP2 | 0.73 | 0.108 |
| PDE4B | ABR | 0.717 | |
| TSTD2 | ABR | 0.717 | 0.072 |
| PDE4B | PSD3 | 0.703 | |
| FAM98C | PSD3 | 0.703 | 0.024 |
| FAM98C | PDE4B | 0.698 | |
| PDE4B | TSTD2 | 0.698 | |
| FAM98C | TSTD2 | 0.698 | 0.078 |
| CASKIN2 | UHRF2 | 0.675 | 0.088 |
| CASKIN2 | CASP2 | 0.675 | 0.05 |
| AKAP10 | CASKIN2 | 0.675 | 0.08 |
| N4BP2 | UHRF2 | 0.675 | 0.084 |
| MAGEA2 | N4BP2 | 0.675 | |
| CASP2 | N4BP2 | 0.675 | 0.11 |
| ITPKC | ABR | 0.675 | 0.034 |
| AKAP10 | N4BP2 | 0.675 | 0.11 |
| CASKIN2 | MAGEA2 | 0.675 | |
| PDE4B | N4BP2 | 0.656 | |
| CASKIN2 | ITPKC | 0.652 | 0.084 |
| ITPKC | N4BP2 | 0.652 | 0.108 |
| CASKIN2 | PSD3 | 0.644 | 0.108 |
| KIF11 | UHRF2 | 0.64 | 0.084 |
| AKAP10 | TSTD2 | 0.633 | 0.088 |
| AKAP10 | ABR | 0.612 | 0.07 |
| PSD3 | TSTD2 | 0.602 | 0.11 |
| FAM98C | ABR | 0.57 | 0.034 |
| CASKIN2 | N4BP2 | 0.489 | 0.116 |
| ABR | UHRF2 | 0.478 | 0.028 |
| MAGEA2 | PDE4B | 0.468 | |
| MAGEA2 | TSTD2 | 0.468 | |
| FAM98C | MAGEA2 | 0.468 | |
| AKAP10 | PDE4B | 0.455 | |
| PDE4B | UHRF2 | 0.455 | |
| FAM98C | UHRF2 | 0.455 | 0.088 |
| TSTD2 | UHRF2 | 0.455 | 0.082 |
| MAGEA2 | ABR | 0.455 | |
| AKAP10 | FAM98C | 0.455 | 0.09 |
| PSD3 | N4BP2 | 0.442 | 0.114 |
| MAGEA2 | PSD3 | 0.418 | |
| FAM98C | CASP2 | 0.418 | 0.144 |
| PDE4B | CASP2 | 0.418 | |
| ABR | CASP2 | 0.418 | 0.026 |
| TSTD2 | CASP2 | 0.418 | 0.09 |
| PSD3 | UHRF2 | 0.405 | 0.064 |
| PSD3 | CASP2 | 0.401 | 0.064 |
| MAGEA2 | UHRF2 | 0.401 | |
| KIF11 | CASKIN2 | 0.4 | 0.116 |
| CASKIN2 | ABR | 0.388 | 0.066 |
| KIF11 | TOMM34 | 0.385 | 0.084 |
| PSD3 | ITPKC | 0.364 | 0.078 |
| PDE4B | ITPKC | 0.364 | |
| AKAP10 | ITPKC | 0.364 | 0.088 |
| ITPKC | UHRF2 | 0.364 | 0.088 |
| TSTD2 | ITPKC | 0.364 | 0.104 |
| FAM98C | ITPKC | 0.364 | 0.054 |
| CASP2 | UHRF2 | 0.356 | 0.068 |
| AKAP10 | CASP2 | 0.356 | 0.09 |
| ITPKC | CASP2 | 0.356 | 0.086 |
| AKAP10 | MAGEA2 | 0.356 | |
| AKAP10 | UHRF2 | 0.343 | 0.064 |
| MAGEA2 | ITPKC | 0.343 | |
| MAGEA2 | CASP2 | 0.334 | |
| KIF11 | ITPKC | 0.292 | 0.054 |
| KIF11 | PDE4B | 0.267 | |
| KIF11 | TSTD2 | 0.267 | 0.124 |
| KIF11 | CASP2 | 0.252 | 0.05125 |
| KIF11 | MAGEA2 | 0.248 | |
| AKAP10 | KIF11 | 0.247 | 0.082 |
| PSD3 | ABR | 0.236 | 0.034 |
| ABR | N4BP2 | 0.187 | 0.052 |
| ABR | TOMM34 | 0.15 | 0.066 |
| KIF11 | PSD3 | 0.14 | 0.112 |
| CASKIN2 | TOMM34 | 0.129 | 0.07 |
| N4BP2 | TOMM34 | 0.129 | 0.048 |
| KIF11 | FAM98C | 0.122 | 0.058 |
| KIF11 | N4BP2 | 0.118 | 0.134 |
| PDE4B | TOMM34 | 0.117 | |
| FAM98C | TOMM34 | 0.117 | 0.05 |
| TSTD2 | TOMM34 | 0.117 | 0.079 |
| PSD3 | TOMM34 | 0.113 | 0.032 |
| ITPKC | TOMM34 | 0.096 | 0.05 |
| KIF11 | ABR | 0.076 | 0.0920869565217 |
| UHRF2 | TOMM34 | 0.076 | 0.022 |
| MAGEA2 | TOMM34 | 0.076 | |
| CASP2 | TOMM34 | 0.074 | 0.018 |
| AKAP10 | TOMM34 | 0.074 | 0.08 |
Related Complexes