hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07835.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NKTR | NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase) | 5 | UniProt NCBI |
| SRSF1 | Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit) | 5 | UniProt NCBI |
| SRSF11 | Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11) | 5 | UniProt NCBI |
| SRSF9 | Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9) | 5 | UniProt NCBI |
| U2AF2 | Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72187 | 3.67150180564e-05 | 0.75 | SRSF11 SRSF1 SRSF9 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 5.55513549806e-05 | 0.75 | SRSF11 SRSF1 SRSF9 | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 7.65476877178e-05 | 0.75 | SRSF11 SRSF1 SRSF9 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.000110531761496 | 0.75 | SRSF11 SRSF1 SRSF9 | Transport of Mature Transcript to Cytoplasm |
| CORUM:351 | 0.00029210434484 | 0.75 | SRSF11 SRSF1 SRSF9 | Spliceosome |
| REAC:R-HSA-72163 | 0.00185188916926 | 0.75 | SRSF11 SRSF1 SRSF9 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.002052480752 | 0.75 | SRSF11 SRSF1 SRSF9 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.00469213914253 | 0.75 | SRSF11 SRSF1 SRSF9 | Processing of Capped Intron-Containing Pre-mRNA |
| WP:WP411 | 0.0186440023495 | 0.5 | SRSF1 SRSF9 | mRNA processing |
| KEGG:03040 | 0.0192212154966 | 0.5 | SRSF1 SRSF9 | Spliceosome |
| HPA:0090183 | 0.0296286402726 | 0.75 | SRSF11 SRSF1 SRSF9 | cerebellum; cells in granular layer[High] |
| HPA:0570812 | 0.0387789758455 | 1.0 | SRSF11 NKTR SRSF9 SRSF1 | testis; spermatogonia cells[>=Medium] |
| HPA:0130053 | 0.0399997027243 | 1.0 | SRSF11 NKTR SRSF9 SRSF1 | colon; glandular cells[High] |
| CORUM:6073 | 0.049938562206 | 0.25 | SRSF9 | SRSF9-SRSF6 complex |
| CORUM:6261 | 0.049938562206 | 0.25 | SRSF1 | Histone-2-Histone-4-ASF1-MCM2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SRSF9 | SRSF1 | 0.999 | 0.678 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| NKTR | SRSF1 | 0.998 | 0.292 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| U2AF2 | SRSF1 | 0.996 | 0.916 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| SRSF11 | SRSF1 | 0.994 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| NKTR | SRSF9 | 0.993 | 0.13 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| SRSF11 | U2AF2 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| SRSF11 | SRSF9 | 0.876 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| U2AF2 | SRSF9 | 0.822 | 0.58 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| SRSF11 | NKTR | 0.507 | bioplex_WMM bioplex3_WMM WMM_only | |
| U2AF2 | NKTR | 0.459 | 0.31 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes