hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07844.1
Complex Portal: CPX-24438
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5) | 5 | UniProt NCBI |
| HOXC8 | Homeobox protein Hox-C8 (Homeobox protein Hox-3A) | 5 | UniProt NCBI |
| MAPK8IP2 | C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2) | 5 | UniProt NCBI |
| MAPK8IP1 | C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1) | 5 | UniProt NCBI |
| MAPK8IP3 | C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6994 | 1.36501667663e-05 | 0.4 | MAPK8IP2 MAPK8IP1 | JIP1-JIP2 complex |
| GO:0005078 | 0.000115261178119 | 0.6 | MAPK8IP2 MAPK8IP1 MAPK8IP3 | MAP-kinase scaffold activity |
| GO:0008432 | 0.000115261178119 | 0.6 | MAPK8IP2 MAPK8IP1 MAPK8IP3 | JUN kinase binding |
| WP:WP382 | 0.00157746248845 | 0.6 | MAPK8IP2 MAPK8IP1 MAPK8IP3 | MAPK signaling pathway |
| KEGG:04010 | 0.00215031496116 | 0.6 | MAPK8IP2 MAPK8IP1 MAPK8IP3 | MAPK signaling pathway |
| GO:0019894 | 0.00350285844735 | 0.6 | MAPK8IP2 MAPK8IP1 MAPK8IP3 | kinesin binding |
| CORUM:4089 | 0.0498708842806 | 0.2 | HOXC8 | SMAD6-HOXC8 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAPK8IP2 | MAPK8IP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| MAPK8IP2 | MAPK8IP3 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| HOXC8 | MAPK8IP1 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MAPK8IP1 | MAPK8IP3 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| MAPK8IP1 | PGAM5 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| MAPK8IP2 | HOXC8 | 0.84 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| HOXC8 | MAPK8IP3 | 0.131 | bioplex3_WMM WMM_only | ||
| HOXC8 | PGAM5 | 0.09 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| MAPK8IP2 | PGAM5 | 0.063 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAPK8IP3 | PGAM5 | 0.021 | 0.026 | bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
Related Complexes