hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07845.1
Complex Portal: CPX-23548
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DSC3 | Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP) | 5 | UniProt NCBI |
| KCT2 | Keratinocyte-associated transmembrane protein 2 | 2 | UniProt NCBI |
| ABHD14A | Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A) | 3 | UniProt NCBI |
| HSPA13 | Heat shock 70 kDa protein 13 (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein) | 5 | UniProt NCBI |
| TMEM59 | Transmembrane protein 59 (Liver membrane-bound protein) | 5 | UniProt NCBI |
| CPD | Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) | 5 | UniProt NCBI |
| B4GALT5 | Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (EC 2.4.1.-) (Beta-1,4-GalT II) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5) | 5 | UniProt NCBI |
| IL20RB | Interleukin-20 receptor subunit beta (IL-20 receptor subunit beta) (IL-20R-beta) (IL-20RB) (Fibronectin type III domain containing 6) (FNDC6) (IL-20R2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9696273 | 0.0367988237757 | 0.25 | TMEM59 CPD | RND1 GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HSPA13 | B4GALT5 | 0.996 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| B4GALT5 | TMEM59 | 0.995 | 0.154 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KCT2 | IL20RB | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| B4GALT5 | IL20RB | 0.994 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TMEM59 | CPD | 0.987 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM | |
| TMEM59 | IL20RB | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ABHD14A | TMEM59 | 0.984 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HSPA13 | ABHD14A | 0.98 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| B4GALT5 | DSC3 | 0.974 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DSC3 | TMEM59 | 0.96 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| HSPA13 | TMEM59 | 0.959 | 0.076 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ABHD14A | CPD | 0.959 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KCT2 | TMEM59 | 0.955 | 0.278 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| B4GALT5 | CPD | 0.952 | 0.14 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| B4GALT5 | ABHD14A | 0.947 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DSC3 | CPD | 0.944 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| DSC3 | ABHD14A | 0.92 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| HSPA13 | CPD | 0.916 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| B4GALT5 | KCT2 | 0.89 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only | |
| DSC3 | IL20RB | 0.605 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| HSPA13 | DSC3 | 0.567 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCT2 | ABHD14A | 0.269 | bioplex_WMM bioplex3_WMM WMM_only | ||
| HSPA13 | KCT2 | 0.076 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only | |
| DSC3 | KCT2 | 0.069 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| KCT2 | CPD | 0.033 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| CPD | IL20RB | 0.018 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes