hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07864.1

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
TUBA1B	Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]	5	UniProt NCBI
DNAJA1	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	5	UniProt NCBI
CAPS	Calcyphosin (Calcyphosine)	5	UniProt NCBI
TUBA4B	Putative tubulin-like protein alpha-4B (EC 3.6.5.-) (Alpha-tubulin 4B)	3	UniProt NCBI
RPS27	Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1)	5	UniProt NCBI
TUBB6	Tubulin beta-6 chain (Tubulin beta class V)	5	UniProt NCBI
TTC5	Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap)	5	UniProt NCBI
TUBB	Tubulin beta chain (Tubulin beta-5 chain)	5	UniProt NCBI
TUBB3	Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)	5	UniProt NCBI
CAD	Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	5	UniProt NCBI
ARL2	ADP-ribosylation factor-like protein 2	5	UniProt NCBI
TUBA1A	Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]	5	UniProt NCBI
TUBB4A	Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)	5	UniProt NCBI
FAS	Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)	5	UniProt NCBI
TBCD	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-389977	7.98292105939e-18	0.571428571429	TUBB4A TUBA1B ARL2 TUBA1A TUBB6 TUBA4B TBCD TUBB3	Post-chaperonin tubulin folding pathway
REAC:R-HSA-190840	1.15163494637e-12	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
REAC:R-HSA-391251	1.47765829597e-12	0.571428571429	TUBB4A TUBA1B ARL2 TUBA1A TUBB6 TUBA4B TBCD TUBB3	Protein folding
REAC:R-HSA-190872	1.68236825488e-12	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Transport of connexons to the plasma membrane
REAC:R-HSA-3371497	4.48497871179e-12	0.5	DNAJA1 TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-389960	1.09504884157e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Formation of tubulin folding intermediates by CCT/TriC
REAC:R-HSA-9619483	1.09504884157e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Activation of AMPK downstream of NMDARs
WP:WP2359	1.33942170345e-11	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	Parkin ubiquitin proteasomal system pathway
REAC:R-HSA-190861	2.3261855864e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Gap junction assembly
REAC:R-HSA-5626467	2.93163839677e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	RHO GTPases activate IQGAPs
REAC:R-HSA-9668328	2.93163839677e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Sealing of the nuclear envelope (NE) by ESCRT-III
REAC:R-HSA-389958	5.58478302488e-11	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REAC:R-HSA-8955332	1.69659108848e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Carboxyterminal post-translational modifications of tubulin
REAC:R-HSA-9609736	1.69659108848e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Assembly and cell surface presentation of NMDA receptors
REAC:R-HSA-190828	2.00411955275e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Gap junction trafficking
REAC:R-HSA-157858	2.35667918348e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Gap junction trafficking and regulation
REAC:R-HSA-380320	2.4649605986e-10	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	Recruitment of NuMA to mitotic centrosomes
REAC:R-HSA-9646399	2.75938331605e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Aggrephagy
WP:WP2272	3.54733614763e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Pathogenic Escherichia coli infection
REAC:R-HSA-437239	5.73480966782e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Recycling pathway of L1
REAC:R-HSA-68877	6.85223103876e-10	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Mitotic Prometaphase
REAC:R-HSA-6811436	9.7107467011e-10	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-9648025	1.26186974344e-09	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-983189	1.57532036404e-09	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Kinesins
KEGG:04540	1.71584128623e-09	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Gap junction
REAC:R-HSA-2500257	2.05607939758e-09	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-5663220	3.81987073583e-09	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	RHO GTPases Activate Formins
REAC:R-HSA-2995410	6.0498711473e-09	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Nuclear Envelope (NE) Reassembly
REAC:R-HSA-438064	6.63221852594e-09	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Post NMDA receptor activation events
REAC:R-HSA-1445148	7.26043827625e-09	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Translocation of SLC2A4 (GLUT4) to the plasma membrane
REAC:R-HSA-9663891	1.21610225033e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Selective autophagy
REAC:R-HSA-8852276	1.31971770011e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	The role of GTSE1 in G2/M progression after G2 checkpoint
REAC:R-HSA-442755	1.8105874615e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-390466	2.62896034543e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Chaperonin-mediated protein folding
CORUM:6715	3.65216022462e-08	0.214285714286	TBCD TUBB ARL2	TBCD-ARL2-tubulin(beta)-TBCE complex
CORUM:6713	3.65216022462e-08	0.214285714286	TBCD TUBB ARL2	TBCD-ARL2-tubulin(beta) complex
CORUM:6703	3.65216022462e-08	0.214285714286	TUBA1A TUBB TBCD	TBCD-tubulin(alpha)-tubulin(beta) complex
REAC:R-HSA-2467813	4.00222787414e-08	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Separation of Sister Chromatids
GO:0005200	4.3876298655e-08	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	structural constituent of cytoskeleton
REAC:R-HSA-6811434	4.56465855711e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	COPI-dependent Golgi-to-ER retrograde traffic
REAC:R-HSA-5617833	4.83317664607e-08	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	Cilium Assembly
REAC:R-HSA-69275	4.83317664607e-08	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	G2/M Transition
GO:0005525	5.08343865916e-08	0.571428571429	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TUBB3 TUBB6	GTP binding
REAC:R-HSA-453274	5.20454566465e-08	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	Mitotic G2-G2/M phases
REAC:R-HSA-6807878	5.54372152959e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	COPI-mediated anterograde transport
KEGG:04145	7.62147248785e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Phagosome
REAC:R-HSA-373760	8.02956523733e-08	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	L1CAM interactions
GO:0032561	1.27112984076e-07	0.571428571429	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TUBB3 TUBB6	guanyl ribonucleotide binding
GO:0019001	1.3244452773e-07	0.571428571429	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TUBB3 TUBB6	guanyl nucleotide binding
REAC:R-HSA-68882	1.54308975287e-07	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Mitotic Anaphase
REAC:R-HSA-2555396	1.59219107421e-07	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Mitotic Metaphase and Anaphase
REAC:R-HSA-68886	1.65136100303e-07	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	M Phase
REAC:R-HSA-2132295	1.85185170223e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	MHC class II antigen presentation
REAC:R-HSA-9609690	2.15973251941e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	HCMV Early Events
REAC:R-HSA-5620924	2.32340175534e-07	0.357142857143	TUBA1B TUBA1A TUBB4A TUBB6 TUBB3	Intraflagellar transport
KEGG:04814	2.62362333162e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Motor proteins
REAC:R-HSA-1632852	2.90382252439e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Macroautophagy
REAC:R-HSA-8856688	2.90382252439e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Golgi-to-ER retrograde transport
KEGG:05130	2.9298574511e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Pathogenic Escherichia coli infection
REAC:R-HSA-9612973	5.73640800312e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Autophagy
REAC:R-HSA-9609646	5.98665439208e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	HCMV Infection
REAC:R-HSA-199977	6.24589048804e-07	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	ER to Golgi Anterograde Transport
REAC:R-HSA-1852241	6.66594793361e-07	0.5	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TUBB3 TUBB6	Organelle biogenesis and maintenance
GO:0035639	1.01512976319e-06	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	purine ribonucleoside triphosphate binding
REAC:R-HSA-983231	1.09714862534e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Factors involved in megakaryocyte development and platelet production
REAC:R-HSA-195258	1.11193942408e-06	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	RHO GTPase Effectors
REAC:R-HSA-112314	1.13991774774e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Neurotransmitter receptors and postsynaptic signal transmission
GO:0005874	1.77095500877e-06	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	microtubule
KEGG:05132	1.82764235428e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Salmonella infection
REAC:R-HSA-69278	1.86129784701e-06	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Cell Cycle, Mitotic
REAC:R-HSA-948021	1.89957708929e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Transport to the Golgi and subsequent modification
REAC:R-HSA-389957	2.56438209678e-06	0.285714285714	TUBA1A TUBB4A TUBB6 TUBB3	Prefoldin mediated transfer of substrate to CCT/TriC
KEGG:05012	2.62250504907e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Parkinson disease
KEGG:05020	3.1160255294e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Prion disease
GO:0032555	3.1918296392e-06	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	purine ribonucleotide binding
GO:0032553	3.70604736072e-06	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	ribonucleotide binding
REAC:R-HSA-6811442	3.7906731358e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Intra-Golgi and retrograde Golgi-to-ER traffic
GO:0000226	4.53239087196e-06	0.642857142857	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	microtubule cytoskeleton organization
WP:WP2059	4.60076374977e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Alzheimer 39 s disease and miRNA effects
WP:WP5124	4.60076374977e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Alzheimer 39 s disease
REAC:R-HSA-112315	5.12842785585e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Transmission across Chemical Synapses
KEGG:05016	5.67073722415e-06	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Huntington disease
HP:0025102	7.43578667073e-06	0.214285714286	TUBA1A TUBB TUBB3	Dysgenesis of the basal ganglia
REAC:R-HSA-5610787	9.28859147264e-06	0.357142857143	TUBA1B TUBA1A TUBB4A TUBB6 TUBB3	Hedgehog 'off' state
REAC:R-HSA-1640170	9.4120135736e-06	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Cell Cycle
GO:0017076	9.54617803424e-06	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	purine nucleotide binding
KEGG:05014	1.62970866999e-05	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Amyotrophic lateral sclerosis
REAC:R-HSA-9824446	1.79625518509e-05	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Viral Infection Pathways
KEGG:05010	2.16448235601e-05	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Alzheimer disease
REAC:R-HSA-2262752	2.23362077566e-05	0.571428571429	DNAJA1 TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Cellular responses to stress
REAC:R-HSA-8953897	2.40708226254e-05	0.571428571429	DNAJA1 TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Cellular responses to stimuli
REAC:R-HSA-5358351	2.82461810727e-05	0.357142857143	TUBA1B TUBA1A TUBB4A TUBB6 TUBB3	Signaling by Hedgehog
REAC:R-HSA-422475	3.20487468126e-05	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Axon guidance
GO:0000166	3.28339132767e-05	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	nucleotide binding
GO:1901265	3.33092946507e-05	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	nucleoside phosphate binding
REAC:R-HSA-446203	3.70198674348e-05	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Asparagine N-linked glycosylation
REAC:R-HSA-9675108	4.11711376314e-05	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Nervous system development
CORUM:6697	4.44741811353e-05	0.142857142857	TBCD ARL2	ARL2-TBCD complex
CORUM:6455	4.44741811353e-05	0.142857142857	TBCD ARL2	ARL2-TBCD complex
REAC:R-HSA-112316	5.02440887012e-05	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Neuronal System
GO:0099513	5.51473584796e-05	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	polymeric cytoskeletal fiber
GO:1901363	6.047611568e-05	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	heterocyclic compound binding
KEGG:05022	6.86387610025e-05	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBB3 TUBB	Pathways of neurodegeneration - multiple diseases
GO:0097367	7.87383591929e-05	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	carbohydrate derivative binding
REAC:R-HSA-5663205	8.85868576474e-05	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Infectious disease
GO:0007017	9.42665309631e-05	0.642857142857	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	microtubule-based process
GO:0015630	9.58917450823e-05	0.714285714286	TUBB4A DNAJA1 TUBA1B ARL2 TUBA1A TUBB6 TUBA4B TBCD TUBB3 TUBB	microtubule cytoskeleton
GO:0043167	0.000175919120351	0.785714285714	TUBB4A CAD TUBA1B ARL2 TUBA1A TUBB CAPS TUBA4B RPS27 TUBB3 TUBB6	ion binding
REAC:R-HSA-194315	0.000197956208106	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Signaling by Rho GTPases
REAC:R-HSA-9716542	0.000229648632733	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
GO:0005198	0.000255911086511	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	structural molecule activity
GO:0043168	0.00036374058095	0.642857142857	TUBB4A TUBA1B TUBA4B ARL2 TUBA1A TUBB CAD TUBB3 TUBB6	anion binding
GO:0099512	0.000519301842477	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	supramolecular fiber
GO:0099081	0.000572714736533	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	supramolecular polymer
GO:0036094	0.000583775556912	0.785714285714	TUBB4A CAD TUBA1B ARL2 TUBA1A TUBB CAPS TUBA4B RPS27 TUBB3 TUBB6	small molecule binding
REAC:R-HSA-392499	0.00129289442112	0.642857142857	TUBB4A TUBA1B ARL2 TUBA1A TBCD TUBB6 TUBA4B RPS27 TUBB3	Metabolism of proteins
REAC:R-HSA-109582	0.00137737033609	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Hemostasis
REAC:R-HSA-1266738	0.00152311837204	0.5	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B RPS27 TUBB3	Developmental Biology
REAC:R-HSA-199991	0.00228040119927	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Membrane Trafficking
HP:0020214	0.00271806002538	0.142857142857	TUBA1A TUBB3	Startle-induced seizure
REAC:R-HSA-5653656	0.0031153160115	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Vesicle-mediated transport
GO:0000278	0.00397584498067	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	mitotic cell cycle
GO:0005856	0.00502071297556	0.714285714286	TUBB4A DNAJA1 TUBA1B ARL2 TUBA1A TUBB6 TUBA4B TBCD TUBB3 TUBB	cytoskeleton
REAC:R-HSA-1280218	0.00530303417868	0.428571428571	TUBA1B TUBB4A TUBA1A TUBB6 TUBA4B TUBB3	Adaptive Immune System
REAC:R-HSA-1643685	0.00536435522159	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B RPS27 TUBB3 TUBB6	Disease
GO:0007010	0.00540172587396	0.642857142857	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	cytoskeleton organization
HP:0012502	0.0054331440558	0.142857142857	TUBA1A TUBB3	Abnormality of the internal capsule
HPA:0500703	0.00690838824485	0.285714285714	TUBA1B TUBA1A TUBB TUBB3	soft tissue 1; peripheral nerve[High]
REAC:R-HSA-380259	0.00868002537299	0.214285714286	TUBA1A TUBB TUBB4A	Loss of Nlp from mitotic centrosomes
REAC:R-HSA-380284	0.00868002537299	0.214285714286	TUBA1A TUBB TUBB4A	Loss of proteins required for interphase microtubule organization from the centrosome
HP:0012241	0.00905028290189	0.142857142857	TUBA1A TUBB3	Levator palpebrae superioris atrophy
HP:0025309	0.00905028290189	0.142857142857	TUBA1A TUBB3	Abnormal pupil shape
HP:0025721	0.00905028290189	0.142857142857	TUBA1A TUBB3	Limited vertical extraocular movement
HP:0030534	0.00905028290189	0.142857142857	TUBA1A TUBB3	Abnormal best corrected visual acuity test
HP:0007831	0.00905028290189	0.142857142857	TUBA1A TUBB3	Nonprogressive restrictive external ophthalmoplegia
HP:0001477	0.00905028290189	0.142857142857	TUBA1A TUBB3	Compensatory chin elevation
HP:0001491	0.00905028290189	0.142857142857	TUBA1A TUBB3	Congenital fibrosis of extraocular muscles
HP:3000072	0.00905028290189	0.142857142857	TUBA1A TUBB3	Abnormal levator palpebrae superioris morphology
REAC:R-HSA-8854518	0.00992155905408	0.214285714286	TUBA1A TUBB TUBB4A	AURKA Activation by TPX2
HPA:0500112	0.0114522722636	0.5	DNAJA1 TUBA1B TUBA1A TUBB CAD ARL2 TUBB6	soft tissue 1; chondrocytes[>=Medium]
HP:0032398	0.0135679927646	0.142857142857	TUBA1A TUBB3	Dysgyria
REAC:R-HSA-380287	0.014332962955	0.214285714286	TUBA1A TUBB TUBB4A	Centrosome maturation
REAC:R-HSA-380270	0.014332962955	0.214285714286	TUBA1A TUBB TUBB4A	Recruitment of mitotic centrosome proteins and complexes
GO:0007049	0.0167270623364	0.642857142857	TUBB4A TUBA1B ARL2 TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	cell cycle
GO:0099080	0.0169280619415	0.571428571429	TUBA1B TUBB4A TUBA1A TUBB TUBA4B TBCD TUBB3 TUBB6	supramolecular complex
HP:0001338	0.0169530104322	0.214285714286	TUBA1A TUBB TUBB3	Partial agenesis of the corpus callosum
REAC:R-HSA-2565942	0.0172617996318	0.214285714286	TUBA1A TUBB TUBB4A	Regulation of PLK1 Activity at G2/M Transition
HP:0002465	0.0179918598869	0.285714285714	CAD TBCD TUBB3 TUBB4A	Poor speech
REAC:R-HSA-5620912	0.024241811691	0.214285714286	TUBA1A TUBB TUBB4A	Anchoring of the basal body to the plasma membrane
HP:0000542	0.0252991987251	0.142857142857	TUBA1A TUBB3	Impaired ocular adduction
HP:0011347	0.0325097356017	0.142857142857	TUBA1A TUBB3	Abnormality of ocular abduction
HP:0008049	0.0325097356017	0.142857142857	TUBA1A TUBB3	Abnormality of the extraocular muscles
HP:0025186	0.0325097356017	0.142857142857	TUBA1A TUBB3	Marcus Gunn jaw winking synkinesis
HP:0000473	0.0375752662048	0.214285714286	TUBA1A TUBB3 TUBB4A	Torticollis
GO:0045171	0.0379796902047	0.285714285714	TUBB4A TUBB3 TUBB6 TUBB	intercellular bridge
HP:0011451	0.0409433754462	0.214285714286	TBCD TUBB TUBB3	Primary microcephaly
HP:0011006	0.0426993727844	0.214285714286	TUBA1A TUBB3 TUBB4A	Abnormal morphology of the musculature of the neck
HP:0002977	0.0427071482482	0.571428571429	TTC5 CAD TUBB4A TUBA1A TUBB TBCD RPS27 TUBB3	Aplasia/Hypoplasia involving the central nervous system
HPA:0471423	0.0435147555318	0.142857142857	TUBA1B TUBA1A	skin 2; eccrine glands[High]
HP:0000252	0.0467564631862	0.5	TTC5 TUBB4A TUBA1A TUBB TBCD RPS27 TUBB3	Microcephaly
HP:0040195	0.0496738986092	0.5	TTC5 TUBB4A TUBA1A TUBB TBCD RPS27 TUBB3	Decreased head circumference

Edges

Protein 1	Protein 2	Score	ProteomeHD
ARL2	TBCD	1.0	0.2
DNAJA1	TUBB	0.999	0.374
TUBB	TBCD	0.999	0.4
ARL2	TUBB	0.998	0.098
TUBB	CAD	0.998	0.352
TUBB6	TUBB	0.996	0.982
TUBB3	TUBB6	0.996	0.308
TUBA1B	TUBB	0.995
TUBB3	TUBB	0.995	0.394
TUBB4A	TBCD	0.993	0.3
DNAJA1	TUBA1B	0.993
TUBB	TUBB4A	0.992	0.938
TUBB6	TUBB4A	0.992	0.798
TUBB	FAS	0.992	0.112
TUBB3	TUBA1A	0.991
RPS27	TUBB6	0.99	0.256
RPS27	TUBB	0.99	0.49
DNAJA1	TUBB3	0.988	0.32
TUBB	TTC5	0.985	0.236
TUBB3	CAD	0.984	0.332
TUBA1A	TUBB4A	0.982
TUBA1A	TUBB	0.979
TUBA1B	TUBB6	0.977
TUBB6	FAS	0.975	0.224768
RPS27	TUBB4A	0.975	0.264
DNAJA1	TUBA1A	0.968
TUBA1A	TUBA1B	0.967
TUBB6	TTC5	0.966	0.198
RPS27	TUBA1A	0.957
FAS	TBCD	0.956	0.149666666667
CAPS	TUBB6	0.956	0.3
CAPS	TUBB	0.952	0.306608695652
TUBB3	FAS	0.948	0.22
TUBB4A	FAS	0.947	0.164609230769
RPS27	CAD	0.934	0.162
ARL2	TTC5	0.934	0.064
TUBB3	TUBB4A	0.933	0.454
TUBA1A	TTC5	0.92
ARL2	TUBB4A	0.919	0.188
TUBB3	CAPS	0.915	0.142
ARL2	FAS	0.906	0.166
TUBB3	TUBA1B	0.9
TTC5	FAS	0.899	0.11
DNAJA1	TUBB6	0.867	0.298
DNAJA1	TUBB4A	0.866	0.22
DNAJA1	RPS27	0.823	0.238
CAPS	TUBB4A	0.812	0.18
TUBA1A	TUBB6	0.805
TUBB3	TTC5	0.775	0.170162601626
TUBB3	TBCD	0.752	0.13
ARL2	TUBB3	0.742	0.343173015
TUBA1B	CAD	0.74
TTC5	TBCD	0.739	0.036
ARL2	TUBB6	0.716	0.1803
TUBA1A	CAD	0.692
RPS27	TUBA1B	0.628
RPS27	TUBB3	0.619	0.258
TUBB4A	TTC5	0.614	0.312888888889
DNAJA1	CAD	0.506	0.23
RPS27	TBCD	0.5	0.282
TUBA1B	TUBB4A	0.432
TUBA1A	CAPS	0.429
CAD	TUBB4A	0.353	0.294
ARL2	CAPS	0.303	0.062
TUBA1B	TBCD	0.288
TUBB6	TBCD	0.243	0.252
TUBA1A	TBCD	0.226
CAPS	TBCD	0.169	0.118
ARL2	TUBA1A	0.167
DNAJA1	TTC5	0.154	0.128
CAPS	TTC5	0.137	0.072
RPS27	TTC5	0.127	0.21
TUBA1A	FAS	0.113
TUBB6	CAD	0.102	0.272
ARL2	RPS27	0.089	0.144
DNAJA1	FAS	0.084	0.12
RPS27	FAS	0.083	0.202
ARL2	DNAJA1	0.079	0.094
CAPS	FAS	0.066	0.048
DNAJA1	TBCD	0.051	0.226
CAD	TBCD	0.05	0.418
CAD	TTC5	0.044	0.1
TUBA1B	TTC5	0.029
TUBA1B	FAS	0.027
DNAJA1	CAPS	0.019	0.14
ARL2	CAD	0.016	0.07
RPS27	CAPS	0.013	0.148
CAD	FAS	0.01	0.086
TUBA1B	CAPS	0.009
CAPS	CAD	0.005	0.1
ARL2	TUBA1B	0.001

Related Complexes

Genename	Complexes
TUBA1B	huMAP3_02724.1 huMAP3_03810.1 huMAP3_06559.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_07938.1 huMAP3_08094.1 huMAP3_08179.1 huMAP3_09191.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10656.1 huMAP3_10665.1 huMAP3_11156.1 huMAP3_14584.1
DNAJA1	huMAP3_01335.1 huMAP3_02724.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10363.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
CAPS	huMAP3_03106.1 huMAP3_03532.1 huMAP3_04859.1 huMAP3_06197.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11669.1 huMAP3_12525.1 huMAP3_13292.1 huMAP3_14468.1 huMAP3_14491.1 huMAP3_14682.1
TUBA4B	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
RPS27	huMAP3_01409.1 huMAP3_01838.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08023.1 huMAP3_08179.1 huMAP3_08373.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
TUBB6	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TTC5	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1 huMAP3_14884.1
TUBB	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBB3	huMAP3_02722.1 huMAP3_06977.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
CAD	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10103.1 huMAP3_10475.1 huMAP3_10665.1
ARL2	huMAP3_01239.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10142.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_13133.1 huMAP3_14311.1 huMAP3_14884.1
TUBA1A	huMAP3_02724.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBB4A	huMAP3_05787.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
FAS	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12841.1 huMAP3_14311.1
TBCD	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_07864.1