hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07871.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FGFR1 | Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) | 5 | UniProt NCBI |
| FGFR3 | Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) | 5 | UniProt NCBI |
| SECTM1 | Secreted and transmembrane protein 1 (Protein K-12) | 5 | UniProt NCBI |
| JAM3 | Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)] | 5 | UniProt NCBI |
| IGDCC3 | Immunoglobulin superfamily DCC subclass member 3 (Putative neuronal cell adhesion molecule) | 3 | UniProt NCBI |
| CLEC4A | C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367) | 5 | UniProt NCBI |
| ROR1 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1) | 5 | UniProt NCBI |
| SIRPA | Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a) | 5 | UniProt NCBI |
| MT-ND6 | NADH-ubiquinone oxidoreductase chain 6 (EC 7.1.1.2) (NADH dehydrogenase subunit 6) | 5 | UniProt NCBI |
| FGFR2 | Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CLEC4A | ROR1 | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FGFR1 | FGFR2 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CLEC4A | SIRPA | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SECTM1 | CLEC4A | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FGFR3 | FGFR2 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CLEC4A | FGFR2 | 0.989 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| JAM3 | CLEC4A | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CLEC4A | MT-ND6 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IGDCC3 | CLEC4A | 0.97 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| FGFR3 | CLEC4A | 0.97 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FGFR1 | CLEC4A | 0.954 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ROR1 | SIRPA | 0.905 | 0.096 | bioplex3_WMM WMM_only |
| SECTM1 | SIRPA | 0.869 | bioplex3_WMM WMM_only | |
| ROR1 | FGFR2 | 0.761 | 0.226060606061 | bioplex3_WMM WMM_only |
| FGFR2 | SIRPA | 0.734 | 0.104 | bioplex3_WMM WMM_only |
| SECTM1 | ROR1 | 0.656 | bioplex3_WMM WMM_only | |
| ROR1 | MT-ND6 | 0.415 | 0.102 | bioplex3_WMM WMM_only |
| JAM3 | MT-ND6 | 0.415 | 0.128 | bioplex3_WMM WMM_only |
| IGDCC3 | MT-ND6 | 0.415 | bioplex3_WMM WMM_only | |
| JAM3 | IGDCC3 | 0.415 | bioplex3_WMM WMM_only | |
| IGDCC3 | ROR1 | 0.415 | bioplex3_WMM WMM_only | |
| MT-ND6 | SIRPA | 0.415 | 0.088 | bioplex3_WMM WMM_only |
| IGDCC3 | SIRPA | 0.415 | bioplex3_WMM WMM_only | |
| SECTM1 | FGFR2 | 0.283 | bioplex3_WMM WMM_only | |
| FGFR1 | ROR1 | 0.281 | bioplex3_WMM WMM_only | |
| FGFR1 | FGFR3 | 0.266 | bioplex_WMM bioplex3_WMM WMM_only | |
| FGFR3 | ROR1 | 0.239 | bioplex3_WMM WMM_only | |
| FGFR3 | SIRPA | 0.239 | bioplex3_WMM WMM_only | |
| SECTM1 | MT-ND6 | 0.214 | bioplex3_WMM WMM_only | |
| SECTM1 | IGDCC3 | 0.214 | bioplex3_WMM WMM_only | |
| JAM3 | SIRPA | 0.21 | 0.074 | bioplex3_WMM WMM_only |
| FGFR3 | JAM3 | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | |
| JAM3 | FGFR2 | 0.159 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only |
| JAM3 | ROR1 | 0.143 | 0.092 | bioplex3_WMM gupta_WMM WMM_only |
| FGFR1 | SIRPA | 0.142 | bioplex3_WMM WMM_only | |
| FGFR3 | SECTM1 | 0.132 | bioplex3_WMM WMM_only | |
| SECTM1 | JAM3 | 0.108 | bioplex3_WMM WMM_only | |
| FGFR1 | IGDCC3 | 0.092 | bioplex3_WMM WMM_only | |
| IGDCC3 | FGFR2 | 0.078 | bioplex3_WMM WMM_only | |
| MT-ND6 | FGFR2 | 0.078 | 0.15 | bioplex3_WMM WMM_only |
| FGFR3 | IGDCC3 | 0.076 | bioplex3_WMM WMM_only | |
| FGFR3 | MT-ND6 | 0.076 | bioplex3_WMM WMM_only | |
| FGFR1 | SECTM1 | 0.074 | bioplex3_WMM WMM_only | |
| FGFR1 | JAM3 | 0.048 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| FGFR1 | MT-ND6 | 0.041 | bioplex3_WMM gupta_WMM WMM_only |
Related Complexes