hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07873.1
Complex Portal: CPX-22166
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RPS6KA5 | Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) | 5 | UniProt NCBI |
| MAPK4 | Mitogen-activated protein kinase 4 (MAP kinase 4) (MAPK 4) (EC 2.7.11.24) (Extracellular signal-regulated kinase 4) (ERK-4) (MAP kinase isoform p63) (p63-MAPK) | 5 | UniProt NCBI |
| ASTL | Astacin-like metalloendopeptidase (EC 3.4.-.-) (Oocyte astacin) (Ovastacin) (ZP2-proteinase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3915 | 0.00725872233472 | 0.666666666667 | RPS6KA5 MAPK4 | Angiopoietin like protein 8 regulatory pathway |
| WP:WP481 | 0.011426766529 | 0.666666666667 | RPS6KA5 MAPK4 | Insulin signaling |
| WP:WP437 | 0.0115871748317 | 0.666666666667 | RPS6KA5 MAPK4 | EGF EGFR signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ASTL | MAPK4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAPK4 | RPS6KA5 | 0.969 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ASTL | RPS6KA5 | 0.396 | bioplex3_WMM WMM_only |
Related Complexes