hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07883.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RAB17 | Ras-related protein Rab-17 | 5 | UniProt NCBI |
| CHM | Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein) | 5 | UniProt NCBI |
| RAB7B | Ras-related protein Rab-7b | 5 | UniProt NCBI |
| CHML | Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2) | 5 | UniProt NCBI |
| RAB9B | Ras-related protein Rab-9B (Rab-9-like protein) (Rab-9L) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8873719 | 5.35706921361e-08 | 1.0 | RAB9B CHM RAB17 RAB7B | RAB geranylgeranylation |
| REAC:R-HSA-8876198 | 0.000119242757257 | 0.75 | CHM RAB9B RAB7B | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.000284930280132 | 0.75 | CHM RAB9B RAB7B | Rab regulation of trafficking |
| REAC:R-HSA-597592 | 0.0091733555377 | 1.0 | RAB9B CHM RAB17 RAB7B | Post-translational protein modification |
| KEGG:04148 | 0.0189154103852 | 0.5 | RAB7B RAB17 | Efferocytosis |
| REAC:R-HSA-392499 | 0.0339333915692 | 1.0 | RAB9B CHM RAB17 RAB7B | Metabolism of proteins |
| REAC:R-HSA-199991 | 0.0424877030349 | 0.75 | CHM RAB9B RAB7B | Membrane Trafficking |
| CORUM:6956 | 0.049938562206 | 0.25 | CHM | REP-RGGT-Rab complex |
| REAC:R-HSA-5653656 | 0.0499402458571 | 0.75 | CHM RAB9B RAB7B | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CHM | CHML | 0.991 | 0.116 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| RAB7B | CHML | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RAB7B | CHM | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CHM | RAB9B | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RAB17 | CHM | 0.955 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RAB17 | CHML | 0.95 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CHML | RAB9B | 0.685 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes