hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_07886.1

Complex Portal: CPX-13960

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
KCNA10	Potassium voltage-gated channel subfamily A member 10 (Voltage-gated potassium channel subunit Kv1.8)	5	UniProt NCBI
REEP1	Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein)	5	UniProt NCBI
REEP2	Receptor expression-enhancing protein 2	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0002064	0.0270637362845	0.666666666667	REEP1 REEP2	Spastic gait
HP:0002395	0.0349981079563	0.666666666667	REEP1 REEP2	Lower limb hyperreflexia
CORUM:6430	0.0499402709677	0.333333333333	REEP1	ATL2-SPG31 complex
CORUM:6431	0.0499402709677	0.333333333333	REEP1	ATL3-SPG31 complex
CORUM:6534	0.0499402709677	0.333333333333	REEP1	SPG31-SPG33 omplex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
KCNA10	REEP1	0.991			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
REEP1	REEP2	0.984	0.12	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Related Complexes

Genename	Complexes
KCNA10	huMAP3_01098.1 huMAP3_04731.1 huMAP3_06113.1 huMAP3_07886.1 huMAP3_10432.1 huMAP3_10817.1 huMAP3_13006.1 huMAP3_13203.1 huMAP3_15328.1
REEP1	huMAP3_02133.1 huMAP3_03771.1 huMAP3_04731.1 huMAP3_06113.1 huMAP3_06388.1 huMAP3_07886.1 huMAP3_10432.1 huMAP3_10542.1 huMAP3_11105.1 huMAP3_12359.1 huMAP3_14009.1 huMAP3_14175.1
REEP2	huMAP3_06113.1 huMAP3_07886.1 huMAP3_10736.1 huMAP3_14175.1