hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07890.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYRM7 | Complex III assembly factor LYRM7 (LYR motif-containing protein 7) | 5 | UniProt NCBI |
| UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)] | 5 | UniProt NCBI |
| COX7A2 | Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL) | 5 | UniProt NCBI |
| NDUFAF7 | Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4921 | 0.000118867546443 | 0.666666666667 | LYRM7 UQCRFS1 | Mitochondrial complex III assembly |
| GO:0033108 | 0.0120707547584 | 1.0 | NDUFAF7 LYRM7 UQCRFS1 | mitochondrial respiratory chain complex assembly |
| KEGG:04714 | 0.0158142547588 | 0.666666666667 | NDUFAF7 UQCRFS1 | Thermogenesis |
| REAC:R-HSA-611105 | 0.0329299631783 | 0.666666666667 | NDUFAF7 UQCRFS1 | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.049233254294 | 0.666666666667 | NDUFAF7 UQCRFS1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LYRM7 | UQCRFS1 | 0.998 | 0.07 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| NDUFAF7 | UQCRFS1 | 0.992 | 0.118 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| COX7A2 | NDUFAF7 | 0.969 | 0.0963339882122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| COX7A2 | UQCRFS1 | 0.958 | 0.89 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LYRM7 | NDUFAF7 | 0.629 | 0.312 | bioplex_WMM bioplex3_WMM WMM_only |
| LYRM7 | COX7A2 | 0.374 | 0.07 | bioplex3_WMM WMM_only |
Related Complexes