hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07910.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCBP1 | Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) | 5 | UniProt NCBI |
| LUC7L2 | Putative RNA-binding protein Luc7-like 2 | 5 | UniProt NCBI |
| LIN28B | Protein lin-28 homolog B (Lin-28B) | 5 | UniProt NCBI |
| TRA2A | Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A) | 5 | UniProt NCBI |
| SRSF8 | Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 0.0002928242891 | 0.6 | SRSF8 NCBP1 TRA2A | Spliceosome |
| GO:0006396 | 0.0196596851496 | 1.0 | LUC7L2 SRSF8 TRA2A NCBP1 LIN28B | RNA processing |
| GO:0000377 | 0.0264444778619 | 0.8 | LUC7L2 SRSF8 NCBP1 TRA2A | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.0264444778619 | 0.8 | LUC7L2 SRSF8 NCBP1 TRA2A | mRNA splicing, via spliceosome |
| GO:0000375 | 0.0280745884658 | 0.8 | LUC7L2 SRSF8 NCBP1 TRA2A | RNA splicing, via transesterification reactions |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TRA2A | NCBP1 | 0.996 | 0.18 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| SRSF8 | LUC7L2 | 0.992 | 0.232 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| TRA2A | SRSF8 | 0.979 | 0.518 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
| TRA2A | LIN28B | 0.955 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM treiber_WMM |
| NCBP1 | LIN28B | 0.931 | 0.144 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NCBP1 | SRSF8 | 0.875 | 0.7008 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SRSF8 | LIN28B | 0.852 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
| NCBP1 | LUC7L2 | 0.767 | 0.374 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| LIN28B | LUC7L2 | 0.714 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM treiber_WMM |
| TRA2A | LUC7L2 | 0.706 | 0.268 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
Related Complexes