hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07935.1
Complex Portal: CPX-21507
Confidence: High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FKBP8 | Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase) | 5 | UniProt   NCBI |
| ITGB4 | Integrin beta-4 (GP150) (CD antigen CD104) | 5 | UniProt   NCBI |
| RET | Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   CORUM:5526 | 0.0249718442457 | 0.5 | FKBP8 | CALM1-FKBP38-BCL2 complex |
|   WP:WP5342 | 0.0435328773163 | 0.5 | RET | Pathophysiological roles of DUX4 in FSHD1 |
|   CORUM:903 | 0.0499419797295 | 0.5 | RET | RET-Rai complex |
|   CORUM:4158 | 0.0499419797295 | 0.5 | FKBP8 | HSP90-FKBP38-CAM-Ca(2+) complex |
|   CORUM:6953 | 0.0499419797295 | 0.5 | RET | ARTN-GFRA3-RET comples |
|   HP:0032346 | 0.0499436884913 | 0.5 | RET | Cutaneous lichen amyloidosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  ITGB4 |  RET | 0.978 |            |          | hein_WMM     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  RET |  FKBP8 | 0.951 |            |          | bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  ITGB4 |  FKBP8 | 0.114 | 0.044           |          | bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| FKBP8 | huMAP3_07935.1 |
| ITGB4 | huMAP3_05040.1 huMAP3_07935.1 |
| RET | huMAP3_05040.1 huMAP3_07935.1 huMAP3_13767.1 |