hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07940.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOM1 | Target of Myb1 membrane trafficking protein (Target of Myb protein 1) | 5 | UniProt NCBI |
| SPTBN1 | Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1) | 5 | UniProt NCBI |
| SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | 5 | UniProt NCBI |
| SPTBN2 | Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein) | 5 | UniProt NCBI |
| BASP1 | Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-445095 | 5.51556094215e-06 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | Interaction between L1 and Ankyrins |
| GO:0008091 | 1.92180881975e-05 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | spectrin |
| REAC:R-HSA-375165 | 3.5683276241e-05 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | NCAM signaling for neurite out-growth |
| HPA:0100213 | 0.000149064491223 | 0.8 | SPTBN1 BASP1 SPTAN1 SPTBN2 | cerebral cortex; neuropil[High] |
| REAC:R-HSA-6807878 | 0.000441650890858 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | COPI-mediated anterograde transport |
| REAC:R-HSA-373760 | 0.00053040697399 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | L1CAM interactions |
| REAC:R-HSA-199977 | 0.0014678873081 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 0.00255576037195 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-373753 | 0.00318398402781 | 0.4 | SPTBN1 SPTAN1 | Nephrin family interactions |
| REAC:R-HSA-5673001 | 0.00484953278503 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | RAF/MAP kinase cascade |
| REAC:R-HSA-5684996 | 0.00512712329405 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | MAPK1/MAPK3 signaling |
| REAC:R-HSA-5683057 | 0.00773441075999 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | MAPK family signaling cascades |
| REAC:R-HSA-9013424 | 0.00900400267976 | 0.4 | SPTBN1 SPTAN1 | RHOV GTPase cycle |
| REAC:R-HSA-9662361 | 0.00953234360475 | 0.4 | SPTBN1 SPTAN1 | Sensory processing of sound by outer hair cells of the cochlea |
| REAC:R-HSA-9013420 | 0.0100756681589 | 0.4 | SPTBN1 SPTAN1 | RHOU GTPase cycle |
| REAC:R-HSA-446203 | 0.0113314618617 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | Asparagine N-linked glycosylation |
| GO:0030864 | 0.0145266888919 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | cortical actin cytoskeleton |
| REAC:R-HSA-9662360 | 0.0192520251047 | 0.4 | SPTBN1 SPTAN1 | Sensory processing of sound by inner hair cells of the cochlea |
| REAC:R-HSA-9659379 | 0.0224106525753 | 0.4 | SPTBN1 SPTAN1 | Sensory processing of sound |
| REAC:R-HSA-9012999 | 0.0303172193635 | 0.6 | SPTBN1 SPTAN1 BASP1 | RHO GTPase cycle |
| GO:0030863 | 0.0417184596383 | 0.6 | SPTBN1 SPTAN1 SPTBN2 | cortical cytoskeleton |
| HPA:0460202 | 0.0460879152407 | 0.6 | SPTBN1 SPTAN1 BASP1 | skin 1; endothelial cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SPTBN1 | SPTAN1 | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM Malo gupta_WMM fraction treiber_WMM | |
| SPTBN2 | BASP1 | 0.994 | 0.19 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| SPTBN1 | BASP1 | 0.989 | 0.196842105263 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| SPTBN1 | SPTBN2 | 0.983 | 0.66 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM |
| SPTAN1 | SPTBN2 | 0.979 | hein_WMM bioplex_WMM bioplex3_WMM fraction boldt_WMM treiber_WMM | |
| SPTAN1 | BASP1 | 0.977 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TOM1 | SPTBN1 | 0.967 | 0.15 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| TOM1 | BASP1 | 0.966 | 0.06 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| TOM1 | SPTAN1 | 0.96 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TOM1 | SPTBN2 | 0.949 | 0.074 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TOM1 | huMAP3_03460.1 huMAP3_05589.1 huMAP3_07940.1 huMAP3_09165.1 huMAP3_13216.1 huMAP3_13933.1 |
| SPTBN1 | huMAP3_05473.1 huMAP3_07940.1 huMAP3_09165.1 |
| SPTAN1 | huMAP3_05473.1 huMAP3_07940.1 huMAP3_09165.1 |
| SPTBN2 | huMAP3_05473.1 huMAP3_07940.1 huMAP3_09165.1 |
| BASP1 | huMAP3_05473.1 huMAP3_07940.1 huMAP3_09165.1 |