List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_07948.1

Confidence: High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
ELOA	Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3)	5	UniProt   NCBI
CTR9	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)	5	UniProt   NCBI
POLR2G	DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)	5	UniProt   NCBI
CDC73	Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)	5	UniProt   NCBI
IWS1	Protein IWS1 homolog (IWS1-like protein)	5	UniProt   NCBI
GTF2F1	General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)	5	UniProt   NCBI
MYZAP	Myocardial zonula adherens protein (GRINL1A upstream protein) (Gup)	5	UniProt   NCBI
SUPT5H	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)	5	UniProt   NCBI
GTF2F2	General transcription factor IIF subunit 2 (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-75955	1.58997611034e-14	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	RNA Polymerase II Transcription Elongation
REAC:R-HSA-112382	1.58997611034e-14	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	Formation of RNA Pol II elongation complex
REAC:R-HSA-674695	1.74096216418e-13	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	RNA Polymerase II Pre-transcription Events
REAC:R-HSA-167243	2.13574543247e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	Tat-mediated HIV elongation arrest and recovery
REAC:R-HSA-167238	2.13574543247e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	Pausing and recovery of Tat-mediated HIV elongation
REAC:R-HSA-167290	2.80123063934e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	Pausing and recovery of HIV elongation
REAC:R-HSA-167287	2.80123063934e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	HIV elongation arrest and recovery
REAC:R-HSA-167246	8.70007386216e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	Tat-mediated elongation of the HIV-1 transcript
REAC:R-HSA-167200	8.70007386216e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	Formation of HIV-1 elongation complex containing HIV-1 Tat
REAC:R-HSA-167169	8.70007386216e-07	0.5	GTF2F1 SUPT5H ELOA POLR2G	HIV Transcription Elongation
REAC:R-HSA-167152	1.05469981253e-06	0.5	GTF2F1 SUPT5H ELOA POLR2G	Formation of HIV elongation complex in the absence of HIV Tat
REAC:R-HSA-6796648	4.03938085227e-06	0.5	GTF2F1 SUPT5H ELOA POLR2G	TP53 Regulates Transcription of DNA Repair Genes
GO:0016591	5.19986488571e-06	0.625	CDC73 MYZAP CTR9 GTF2F1 POLR2G	RNA polymerase II, holoenzyme
REAC:R-HSA-167172	6.29400255457e-06	0.5	GTF2F1 SUPT5H ELOA POLR2G	Transcription of the HIV genome
GO:0055029	2.44300642267e-05	0.625	CDC73 MYZAP CTR9 GTF2F1 POLR2G	nuclear DNA-directed RNA polymerase complex
GO:0000428	2.58136974103e-05	0.625	CDC73 MYZAP CTR9 GTF2F1 POLR2G	DNA-directed RNA polymerase complex
REAC:R-HSA-73857	2.80793096136e-05	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	RNA Polymerase II Transcription
GO:0030880	3.03441490958e-05	0.625	CDC73 MYZAP CTR9 GTF2F1 POLR2G	RNA polymerase complex
REAC:R-HSA-167242	3.51023480424e-05	0.375	GTF2F1 POLR2G SUPT5H	Abortive elongation of HIV-1 transcript in the absence of Tat
GO:0006368	3.54883058612e-05	0.625	GTF2F1 IWS1 SUPT5H CTR9 CDC73	transcription elongation by RNA polymerase II
REAC:R-HSA-77075	5.92028436306e-05	0.375	GTF2F1 POLR2G SUPT5H	RNA Pol II CTD phosphorylation and interaction with CE
REAC:R-HSA-167160	5.92028436306e-05	0.375	GTF2F1 POLR2G SUPT5H	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
REAC:R-HSA-74160	6.70866002994e-05	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	Gene expression (Transcription)
REAC:R-HSA-72086	7.45572658486e-05	0.375	GTF2F1 POLR2G SUPT5H	mRNA Capping
GO:0006354	7.93494916895e-05	0.625	GTF2F1 IWS1 SUPT5H CTR9 CDC73	DNA-templated transcription elongation
REAC:R-HSA-162599	8.65980296911e-05	0.5	GTF2F1 SUPT5H ELOA POLR2G	Late Phase of HIV Life Cycle
REAC:R-HSA-113418	0.000112766844535	0.375	GTF2F1 POLR2G SUPT5H	Formation of the Early Elongation Complex
REAC:R-HSA-167158	0.000112766844535	0.375	GTF2F1 POLR2G SUPT5H	Formation of the HIV-1 Early Elongation Complex
REAC:R-HSA-162587	0.000123441958688	0.5	GTF2F1 SUPT5H ELOA POLR2G	HIV Life Cycle
CORUM:1167	0.000239030245992	0.25	CTR9 CDC73	Paf complex
GO:0008023	0.000325444840356	0.5	CDC73 SUPT5H ELOA CTR9	transcription elongation factor complex
REAC:R-HSA-162906	0.00072268478922	0.5	GTF2F1 SUPT5H ELOA POLR2G	HIV Infection
REAC:R-HSA-6807505	0.00134205528321	0.375	GTF2F1 POLR2G SUPT5H	RNA polymerase II transcribes snRNA genes
CORUM:2685	0.00216982178847	0.25	GTF2F1 POLR2G	RNA polymerase II (RNAPII)
REAC:R-HSA-3700989	0.00388943076684	0.5	GTF2F1 SUPT5H ELOA POLR2G	Transcriptional Regulation by TP53
HPA:0090181	0.00395759929536	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	cerebellum; cells in granular layer[>=Low]
CORUM:103	0.00407177869695	0.25	GTF2F1 POLR2G	RNA polymerase II holoenzyme complex
CORUM:2825	0.00499769201238	0.25	GTF2F1 POLR2G	BRCA1-RNA polymerase II complex
GO:0140513	0.00521846176444	0.875	CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	nuclear protein-containing complex
GO:0061695	0.00619293428193	0.625	CDC73 MYZAP CTR9 GTF2F1 POLR2G	transferase complex, transferring phosphorus-containing groups
REAC:R-HSA-8851708	0.00849789009901	0.25	GTF2F1 POLR2G	Signaling by FGFR2 IIIa TM
HPA:0510000	0.0118359720879	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	soft tissue 2
HPA:0500000	0.0148623646522	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	soft tissue 1
REAC:R-HSA-1839126	0.0153043597228	0.25	GTF2F1 POLR2G	FGFR2 mutant receptor activation
REAC:R-HSA-6803529	0.0153043597228	0.25	GTF2F1 POLR2G	FGFR2 alternative splicing
HPA:0090161	0.0197252977611	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	cerebellum; Purkinje cells[>=Low]
HPA:0130202	0.0223711503047	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	colon; endothelial cells[>=Medium]
HPA:0630222	0.0249041935213	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	cervix; squamous epithelial cells[>=Medium]
REAC:R-HSA-5655253	0.0257351328695	0.25	GTF2F1 POLR2G	Signaling by FGFR2 in disease
HPA:0440000	0.0294872241715	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	skeletal muscle
HPA:0440341	0.0294872241715	1.0	IWS1 CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	skeletal muscle; myocytes[>=Low]
HPA:0460641	0.0327882750258	0.875	IWS1 CTR9 SUPT5H GTF2F1 POLR2G MYZAP ELOA	skin 1; Langerhans[>=Low]
HPA:0470682	0.0386765077351	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	skin 2; epidermal cells[>=Medium]
REAC:R-HSA-168325	0.04306231829	0.25	GTF2F1 POLR2G	Viral Messenger RNA Synthesis
HPA:0620222	0.0434766817865	0.875	IWS1 CDC73 CTR9 GTF2F1 POLR2G SUPT5H ELOA	vagina; squamous epithelial cells[>=Medium]
HPA:0090162	0.0473766132884	0.875	CDC73 CTR9 GTF2F1 POLR2G MYZAP SUPT5H ELOA	cerebellum; Purkinje cells[>=Medium]
CORUM:153	0.0499436884912	0.125	GTF2F1	TFIIF complex (transcription factor IIF)



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
CTR9	CDC73	1.0	0.786	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     Guru     bioplex3_WMM     boldt     youn_WMM     hein ()     Malo     bioplex3_HCT116     fraction     boldt_WMM
GTF2F2	POLR2G	0.997	0.228	hein_WMM     bioplex3_WMM     youn_WMM     hein ()
GTF2F2	GTF2F1	0.995	0.904	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction     boldt_WMM
POLR2G	GTF2F1	0.995	0.264	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
ELOA	IWS1	0.994	0.198	hein_WMM     bioplex3_WMM     youn_WMM     WMM_only
POLR2G	SUPT5H	0.993	0.484	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
POLR2G	ELOA	0.992	0.086	hein_WMM     bioplex3_WMM     youn_WMM     WMM_only
POLR2G	CDC73	0.99	0.17	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
CTR9	ELOA	0.985	0.342	hein_WMM     bioplex3_WMM     boldt     youn_WMM     hein ()     boldt_WMM
SUPT5H	IWS1	0.978	0.452	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()
POLR2G	IWS1	0.97	0.302	hein_WMM     bioplex_WMM     bioplex3_WMM     WMM_only
POLR2G	MYZAP	0.966		hein_WMM     hein ()
CTR9	IWS1	0.958	0.38	hein_WMM     bioplex3_WMM     youn_WMM     hein ()     fraction
CDC73	ELOA	0.951	0.336	hein_WMM     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     gupta_WMM     boldt_WMM     WMM_only
CDC73	IWS1	0.926	0.286	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     fraction
POLR2G	CTR9	0.888	0.306	hein_WMM     bioplex3_WMM     youn_WMM     hein ()     fraction
SUPT5H	CTR9	0.867	0.614	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     fraction
SUPT5H	ELOA	0.856	0.29	hein_WMM     youn ()     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only
SUPT5H	CDC73	0.849	0.382	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
GTF2F2	SUPT5H	0.804	0.338	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
GTF2F2	MYZAP	0.796		hein_WMM     WMM_only
MYZAP	SUPT5H	0.641		hein_WMM     WMM_only
GTF2F1	MYZAP	0.641		hein_WMM     WMM_only
GTF2F1	SUPT5H	0.627	0.262	hein_WMM     youn ()     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
GTF2F2	IWS1	0.562	0.156	bioplex3_WMM     youn_WMM     WMM_only
GTF2F1	IWS1	0.23	0.246	bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only
GTF2F2	CDC73	0.161	0.416	hein_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only
GTF2F2	ELOA	0.142	0.256	bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only
GTF2F1	ELOA	0.114	0.298	bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only
MYZAP	CDC73	0.063		hein_WMM     WMM_only
GTF2F1	CDC73	0.044	0.32	hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
GTF2F1	CTR9	0.034	0.374	bioplex3_WMM     youn_WMM     WMM_only
GTF2F2	CTR9	0.023	0.478	bioplex3_WMM     youn_WMM     WMM_only





Related Complexes

Genename	Complexes
ELOA	huMAP3_06234.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
CTR9	huMAP3_06234.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
POLR2G	huMAP3_02594.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1 huMAP3_14318.1
CDC73	huMAP3_06234.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
IWS1	huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
GTF2F1	huMAP3_02594.1 huMAP3_07948.1 huMAP3_11018.1
MYZAP	huMAP3_02594.1 huMAP3_07948.1 huMAP3_11018.1 huMAP3_12111.1
SUPT5H	huMAP3_02594.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_11018.1 huMAP3_11092.1 huMAP3_12111.1
GTF2F2	huMAP3_00159.1 huMAP3_02594.1 huMAP3_04078.1 huMAP3_04499.1 huMAP3_07454.1 huMAP3_07749.1 huMAP3_07948.1 huMAP3_09843.1 huMAP3_10292.1 huMAP3_11018.1 huMAP3_11092.1