hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07963.1
Complex Portal: CPX-13117
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RTRAF | RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE) | 5 | UniProt NCBI |
| DEK | Protein DEK | 5 | UniProt NCBI |
| NEMF | Ribosome quality control complex subunit NEMF (Antigen NY-CO-1) (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1) | 5 | UniProt NCBI |
| CAPRIN1 | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) | 5 | UniProt NCBI |
| RTCB | RNA-splicing ligase RtcB homolog (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 0.000136445626745 | 0.4 | RTCB RTRAF | tRNA Splicing Ligase Complex |
| HPA:0100122 | 0.0102868948346 | 1.0 | CAPRIN1 DEK RTRAF RTCB NEMF | cerebral cortex; glial cells[>=Medium] |
| HPA:0530712 | 0.0210155383112 | 1.0 | CAPRIN1 DEK RTRAF RTCB NEMF | spleen; cells in red pulp[>=Medium] |
| HPA:0490692 | 0.0217088069864 | 1.0 | CAPRIN1 DEK RTRAF RTCB NEMF | smooth muscle; smooth muscle cells[>=Medium] |
| REAC:R-HSA-6784531 | 0.0224106525753 | 0.4 | RTCB RTRAF | tRNA processing in the nucleus |
| HPA:0130242 | 0.0355835654206 | 1.0 | CAPRIN1 DEK RTRAF RTCB NEMF | colon; peripheral nerve/ganglion[>=Medium] |
| HPA:0170251 | 0.0422298811316 | 1.0 | CAPRIN1 DEK RTRAF RTCB NEMF | endometrium 2; cells in endometrial stroma[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RTRAF | RTCB | 0.996 | 0.92 |
structurally_consistent (dimer)
|
hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RTRAF | NEMF | 0.978 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| DEK | RTRAF | 0.976 | 0.13 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| NEMF | RTCB | 0.973 | 0.162 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| DEK | RTCB | 0.97 | 0.118 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM | |
| RTRAF | CAPRIN1 | 0.961 | 0.15 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM | |
| DEK | NEMF | 0.883 | 0.062 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CAPRIN1 | RTCB | 0.818 | 0.154 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM WMM_only | |
| NEMF | CAPRIN1 | 0.579 | 0.098 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| DEK | CAPRIN1 | 0.028 | 0.122 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
Related Complexes