hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07965.1
Complex Portal: CPX-22599
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | 5 | UniProt NCBI |
| UBE2L3 | Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3) | 5 | UniProt NCBI |
| GMPS | GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3183 | 0.0249718442456 | 0.333333333333 | PTPN11 | PDGFRA-SHP-2 complex, PDGF stimulated |
| WP:WP2253 | 0.0496447587094 | 0.333333333333 | PTPN11 | Pilocytic astrocytoma |
| CORUM:3186 | 0.0499402709677 | 0.333333333333 | PTPN11 | GRB2-SHP-2 complex, PDGF stimulated |
| CORUM:7441 | 0.0499402709677 | 0.333333333333 | PTPN11 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PTPN11 | GMPS | 0.986 | 0.174 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| GMPS | UBE2L3 | 0.971 | 0.234 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| PTPN11 | UBE2L3 | 0.043 | 0.31 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
Related Complexes