List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_07970.1

Confidence: High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
PHC2	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2)	5	UniProt   NCBI
CBX2	Chromobox protein homolog 2	5	UniProt   NCBI
PHC3	Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3)	5	UniProt   NCBI
PHC1	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)	5	UniProt   NCBI
BMI1	Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)	5	UniProt   NCBI
SCMH1	Polycomb protein SCMH1 (Sex comb on midleg homolog 1)	5	UniProt   NCBI
PCGF2	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)	5	UniProt   NCBI
SFMBT2	Scm-like with four MBT domains protein 2 (Scm-like with 4 MBT domains protein 2)	5	UniProt   NCBI
SCML1	Sex comb on midleg-like protein 1	4	UniProt   NCBI
CBX4	E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2)	5	UniProt   NCBI
CBX7	Chromobox protein homolog 7	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:03083	3.81027603547e-24	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	Polycomb repressive complex
CORUM:116	2.56005634448e-19	0.636363636364	CBX4 PHC3 BMI1 SCMH1 CBX2 PHC2 PHC1	Polycomb repressive complex 1 (PRC1, hPRC-H)
CORUM:115	2.56005634448e-19	0.636363636364	CBX4 PHC3 BMI1 SCMH1 CBX2 PHC2 PHC1	Polycomb repressive complex 1 (PRC1, hPRC-H)
GO:0035102	2.0575963047e-18	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	PRC1 complex
REAC:R-HSA-4655427	1.94583227735e-17	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation of DNA methylation proteins
GO:0031519	1.87806490958e-14	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	PcG protein complex
GO:0000152	2.81904673035e-14	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	nuclear ubiquitin ligase complex
REAC:R-HSA-3899300	3.79514938021e-14	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation of transcription cofactors
REAC:R-HSA-4570464	9.67877465082e-14	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation of RNA binding proteins
REAC:R-HSA-4551638	2.32626650953e-12	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation of chromatin organization proteins
REAC:R-HSA-3108214	3.96764870138e-12	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation of DNA damage response and repair proteins
REAC:R-HSA-8939243	1.70905845824e-11	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
REAC:R-HSA-8943724	3.16445351102e-10	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Regulation of PTEN gene transcription
REAC:R-HSA-3108232	1.24521990781e-09	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMO E3 ligases SUMOylate target proteins
GO:0045892	1.46983440258e-09	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of DNA-templated transcription
REAC:R-HSA-2990846	1.55329772475e-09	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	SUMOylation
GO:1902679	1.66915997233e-09	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of RNA biosynthetic process
GO:0051253	4.929188039e-09	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of RNA metabolic process
GO:0045934	1.49680851934e-08	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of nucleobase-containing compound metabolic process
REAC:R-HSA-2559580	1.55293290349e-08	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Oxidative Stress Induced Senescence
CORUM:5518	2.10621603952e-08	0.272727272727	PHC2 BMI1 PHC1	BMI1-HPH1-HPH2 complex
REAC:R-HSA-6807070	6.40164875459e-08	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	PTEN Regulation
CORUM:5513	8.42140472852e-08	0.272727272727	PHC1 BMI1 CBX4	RING1-Polycomb repressive complex
GO:0000151	1.21767591519e-07	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	ubiquitin ligase complex
REAC:R-HSA-2559583	3.08093107749e-07	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Cellular Senescence
GO:0010558	6.39239512554e-07	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of macromolecule biosynthetic process
GO:0031327	8.18774685687e-07	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of cellular biosynthetic process
GO:0051172	8.67183466821e-07	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of nitrogen compound metabolic process
GO:0009890	8.73414046922e-07	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of biosynthetic process
REAC:R-HSA-8878171	9.50583699138e-07	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Transcriptional regulation by RUNX1
GO:0003682	1.15758694416e-06	0.727272727273	PHC3 BMI1 SCMH1 SFMBT2 PHC2 SCML1 PHC1 PCGF2	chromatin binding
REAC:R-HSA-1257604	1.5951708505e-06	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	PIP3 activates AKT signaling
GO:0042393	1.62498353072e-06	0.636363636364	PHC3 SFMBT2 SCMH1 PHC2 SCML1 CBX2 PHC1	histone binding
REAC:R-HSA-8953750	2.06260783556e-06	0.363636363636	PHC3 PCGF2 BMI1 PHC1	Transcriptional Regulation by E2F6
REAC:R-HSA-9006925	3.72558622692e-06	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Intracellular signaling by second messengers
GO:0031324	6.02546803139e-06	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of cellular metabolic process
GO:0010605	7.41990569824e-06	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of macromolecule metabolic process
GO:0009892	1.75513848712e-05	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of metabolic process
GO:0006355	7.53691247935e-05	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of DNA-templated transcription
GO:2001141	8.05603852332e-05	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of RNA biosynthetic process
GO:0006351	0.000127015524712	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	DNA-templated transcription
GO:0032774	0.000142880142753	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	RNA biosynthetic process
CORUM:1462	0.000205019103882	0.181818181818	PHC2 BMI1	hPRC1L complex
GO:0051252	0.000258182136371	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of RNA metabolic process
GO:1990234	0.000440712414509	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	transferase complex
REAC:R-HSA-212436	0.000544477779925	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	Generic Transcription Pathway
GO:0034654	0.000568973562955	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	nucleobase-containing compound biosynthetic process
GO:0140535	0.000693488303304	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	intracellular protein-containing complex
GO:0018130	0.000695422418697	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	heterocycle biosynthetic process
GO:0019438	0.00070360086061	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	aromatic compound biosynthetic process
GO:0019219	0.000706346376562	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of nucleobase-containing compound metabolic process
GO:1901362	0.000967632092806	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	organic cyclic compound biosynthetic process
REAC:R-HSA-73857	0.0011419141294	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	RNA Polymerase II Transcription
REAC:R-HSA-2262752	0.0013878487786	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Cellular responses to stress
REAC:R-HSA-8953897	0.00146760325906	0.545454545455	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1	Cellular responses to stimuli
REAC:R-HSA-597592	0.00187794059316	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	Post-translational protein modification
REAC:R-HSA-74160	0.00264895687847	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	Gene expression (Transcription)
GO:0016070	0.00308349463476	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	RNA metabolic process
GO:0010468	0.00469739513727	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of gene expression
GO:0048523	0.00485367687722	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of cellular process
GO:0044271	0.0050969753096	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	cellular nitrogen compound biosynthetic process
GO:0010556	0.00661322725549	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of macromolecule biosynthetic process
GO:0140513	0.00704522774331	0.727272727273	CBX4 BMI1 PHC3 CBX2 CBX7 PHC2 PHC1 PCGF2	nuclear protein-containing complex
GO:0031326	0.00842368314941	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of cellular biosynthetic process
GO:0009889	0.00899012714611	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of biosynthetic process
GO:0044877	0.0100155710693	0.727272727273	PHC3 BMI1 SCMH1 SFMBT2 PHC2 SCML1 PHC1 PCGF2	protein-containing complex binding
GO:0048519	0.0106740333161	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	negative regulation of biological process
GO:0090304	0.0119029444692	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	nucleic acid metabolic process
REAC:R-HSA-392499	0.0164010508062	0.636363636364	CBX4 BMI1 PHC3 CBX2 PHC2 PHC1 PCGF2	Metabolism of proteins
GO:0051171	0.0210338225181	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of nitrogen compound metabolic process
GO:0080090	0.0275866537037	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	regulation of primary metabolic process
GO:0006139	0.0379532315546	1.0	CBX4 PHC3 BMI1 SCMH1 CBX2 CBX7 PHC2 SCML1 SFMBT2 PHC1 PCGF2	nucleobase-containing compound metabolic process



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
PHC1	PCGF2	1.0	0.1
PHC2	PCGF2	1.0	0.138
PHC3	PCGF2	1.0	0.24
CBX4	PHC1	1.0	0.182
CBX4	PCGF2	1.0	0.206
PHC1	SCMH1	1.0	0.156
PHC2	PHC1	1.0	0.184
PHC1	BMI1	1.0	0.182628865979
PHC2	BMI1	0.999	0.418
PHC2	PHC3	0.999	0.238
CBX4	BMI1	0.999	0.318
PHC3	PHC1	0.999	0.166
CBX2	PCGF2	0.999	0.146
CBX2	PHC1	0.999	0.13
CBX7	PHC1	0.999
CBX7	PCGF2	0.999
PHC2	CBX7	0.999
CBX7	BMI1	0.998
PCGF2	BMI1	0.998	0.202
PHC2	CBX4	0.998	0.23
PHC3	BMI1	0.998	0.374
PHC3	CBX4	0.998	0.354
SCMH1	PCGF2	0.997	0.116
PHC3	CBX7	0.993
PHC1	SFMBT2	0.99
CBX2	BMI1	0.989	0.256
SCML1	PHC1	0.984
PHC2	CBX2	0.972	0.218
SCML1	PCGF2	0.967
SCMH1	BMI1	0.965	0.162736842105
PHC2	SCMH1	0.886	0.094
PHC3	SCMH1	0.886	0.1
CBX2	SCMH1	0.861	0.152
CBX4	SCMH1	0.829	0.176
PHC3	CBX2	0.827	0.214
CBX4	CBX7	0.737
CBX7	CBX2	0.731
CBX4	CBX2	0.652	0.226
CBX7	SCMH1	0.58
CBX7	SFMBT2	0.572
SCMH1	SFMBT2	0.502
PHC2	SFMBT2	0.502
SFMBT2	PCGF2	0.502
PHC3	SFMBT2	0.35
CBX2	SFMBT2	0.35
SFMBT2	BMI1	0.303
SCML1	SFMBT2	0.303
CBX4	SFMBT2	0.303
SCML1	BMI1	0.265
SCML1	PHC2	0.234
SCML1	CBX7	0.202
SCML1	SCMH1	0.202
SCML1	CBX2	0.198
SCML1	PHC3	0.182
SCML1	CBX4	0.122





Related Complexes

Genename	Complexes
PHC2	huMAP3_02464.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
CBX2	huMAP3_03635.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
PHC3	huMAP3_02464.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
PHC1	huMAP3_03635.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1 huMAP3_14833.1
BMI1	huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
SCMH1	huMAP3_03635.1 huMAP3_05225.1 huMAP3_06373.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
PCGF2	huMAP3_06373.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1
SFMBT2	huMAP3_03635.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1 huMAP3_14833.1
SCML1	huMAP3_01025.1 huMAP3_01972.1 huMAP3_03635.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09181.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_10209.1 huMAP3_11493.1 huMAP3_12829.1
CBX4	huMAP3_02464.1 huMAP3_06040.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_12540.1 huMAP3_14051.1 huMAP3_14179.1
CBX7	huMAP3_02464.1 huMAP3_07122.1 huMAP3_07970.1 huMAP3_09551.1 huMAP3_10162.1 huMAP3_14051.1