hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_07976.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IFNA1 | Interferon alpha-1/13 (IFN-alpha-1/13) (Interferon alpha-D) (LeIF D) | 5 | UniProt NCBI |
| IFNA17 | Interferon alpha-17 (IFN-alpha-17) (Interferon alpha-88) (Interferon alpha-I') (LeIF I) (Interferon alpha-T) | 5 | UniProt NCBI |
| IFNA5 | Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05320 | 0.000126804361689 | 1.0 | IFNA17 IFNA5 | Autoimmune thyroid disease |
| WP:WP4912 | 0.000185152102942 | 1.0 | IFNA17 IFNA5 | SARS coronavirus and innate immunity |
| WP:WP4558 | 0.000253254025863 | 1.0 | IFNA17 IFNA5 | Overview of interferons mediated signaling pathway |
| KEGG:04622 | 0.000338144964505 | 1.0 | IFNA17 IFNA5 | RIG-I-like receptor signaling pathway |
| KEGG:04623 | 0.000392605812153 | 1.0 | IFNA17 IFNA5 | Cytosolic DNA-sensing pathway |
| REAC:R-HSA-912694 | 0.000432316723289 | 1.0 | IFNA17 IFNA5 | Regulation of IFNA/IFNB signaling |
| KEGG:04620 | 0.000608173227025 | 1.0 | IFNA17 IFNA5 | Toll-like receptor signaling pathway |
| REAC:R-HSA-933541 | 0.000693757271364 | 1.0 | IFNA17 IFNA5 | TRAF6 mediated IRF7 activation |
| WP:WP4655 | 0.000885324997976 | 1.0 | IFNA17 IFNA5 | Cytosolic DNA sensing pathway |
| KEGG:04650 | 0.00095688522167 | 1.0 | IFNA17 IFNA5 | Natural killer cell mediated cytotoxicity |
| KEGG:04936 | 0.00123975649005 | 1.0 | IFNA17 IFNA5 | Alcoholic liver disease |
| KEGG:05162 | 0.00123975649005 | 1.0 | IFNA17 IFNA5 | Measles |
| KEGG:04630 | 0.00138428094844 | 1.0 | IFNA17 IFNA5 | JAK-STAT signaling pathway |
| KEGG:05160 | 0.00138428094844 | 1.0 | IFNA17 IFNA5 | Hepatitis C |
| WP:WP75 | 0.00144844277313 | 1.0 | IFNA17 IFNA5 | Toll like receptor signaling pathway |
| WP:WP5095 | 0.00148377064565 | 1.0 | IFNA17 IFNA5 | Overview of proinflammatory and profibrotic mediators |
| KEGG:04217 | 0.00151449927371 | 1.0 | IFNA17 IFNA5 | Necroptosis |
| KEGG:05164 | 0.0016738175743 | 1.0 | IFNA17 IFNA5 | Influenza A |
| KEGG:04621 | 0.001720800216 | 1.0 | IFNA17 IFNA5 | NOD-like receptor signaling pathway |
| KEGG:05152 | 0.001720800216 | 1.0 | IFNA17 IFNA5 | Tuberculosis |
| KEGG:05161 | 0.00176843313648 | 1.0 | IFNA17 IFNA5 | Hepatitis B |
| KEGG:05167 | 0.00228052767407 | 1.0 | IFNA17 IFNA5 | Kaposi sarcoma-associated herpesvirus infection |
| KEGG:05169 | 0.00261899777797 | 1.0 | IFNA17 IFNA5 | Epstein-Barr virus infection |
| KEGG:05417 | 0.00261899777797 | 1.0 | IFNA17 IFNA5 | Lipid and atherosclerosis |
| KEGG:05163 | 0.00298087791786 | 1.0 | IFNA17 IFNA5 | Human cytomegalovirus infection |
| KEGG:05170 | 0.0030120912992 | 1.0 | IFNA17 IFNA5 | Human immunodeficiency virus 1 infection |
| REAC:R-HSA-909733 | 0.0031270340064 | 1.0 | IFNA17 IFNA5 | Interferon alpha/beta signaling |
| KEGG:04060 | 0.0031385705215 | 1.0 | IFNA17 IFNA5 | Cytokine-cytokine receptor interaction |
| WP:WP4630 | 0.00319355454799 | 1.0 | IFNA17 IFNA5 | Measles virus infection |
| KEGG:05171 | 0.0033003273675 | 1.0 | IFNA17 IFNA5 | Coronavirus disease - COVID-19 |
| WP:WP4666 | 0.00396523446209 | 1.0 | IFNA17 IFNA5 | Hepatitis B infection |
| REAC:R-HSA-168928 | 0.00474181386216 | 1.0 | IFNA17 IFNA5 | DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| KEGG:04151 | 0.00662552789826 | 1.0 | IFNA17 IFNA5 | PI3K-Akt signaling pathway |
| KEGG:05165 | 0.00700203931066 | 1.0 | IFNA17 IFNA5 | Human papillomavirus infection |
| REAC:R-HSA-9705671 | 0.0106216630512 | 1.0 | IFNA17 IFNA5 | SARS-CoV-2 activates/modulates innate and adaptive immune responses |
| KEGG:05168 | 0.0109183432505 | 1.0 | IFNA17 IFNA5 | Herpes simplex virus 1 infection |
| WP:WP4172 | 0.015571930313 | 1.0 | IFNA17 IFNA5 | PI3K Akt signaling pathway |
| KEGG:05200 | 0.0161326036311 | 1.0 | IFNA17 IFNA5 | Pathways in cancer |
| REAC:R-HSA-983231 | 0.0209254964166 | 1.0 | IFNA17 IFNA5 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-913531 | 0.0260158976762 | 1.0 | IFNA17 IFNA5 | Interferon Signaling |
| REAC:R-HSA-9705683 | 0.0300366140789 | 1.0 | IFNA17 IFNA5 | SARS-CoV-2-host interactions |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IFNA5 | IFNA17 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IFNA17 | IFNA1 | 0.963 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| IFNA5 | IFNA1 | 0.917 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| IFNA1 | huMAP3_07976.1 huMAP3_10459.1 huMAP3_11921.1 huMAP3_13851.1 |
| IFNA17 | huMAP3_07976.1 huMAP3_10459.1 huMAP3_11921.1 huMAP3_13851.1 |
| IFNA5 | huMAP3_02327.1 huMAP3_07976.1 huMAP3_10459.1 huMAP3_11921.1 huMAP3_13851.1 |