hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_07986.1
Complex Portal: CPX-22347
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MBD6 | Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6) | 4 | UniProt NCBI |
| MBD5 | Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5) | 5 | UniProt NCBI |
| ASXL2 | Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03083 | 4.45704451339e-06 | 1.0 | MBD6 MBD5 ASXL2 | Polycomb repressive complex |
| REAC:R-HSA-5689603 | 5.66851611173e-05 | 1.0 | MBD6 MBD5 ASXL2 | UCH proteinases |
| REAC:R-HSA-5688426 | 0.00118616050146 | 1.0 | MBD6 MBD5 ASXL2 | Deubiquitination |
| GO:0010369 | 0.0140440992017 | 0.666666666667 | MBD6 MBD5 | chromocenter |
| HP:0000378 | 0.023094623718 | 0.666666666667 | ASXL2 MBD5 | Cupped ear |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MBD5 | ASXL2 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MBD6 | ASXL2 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MBD6 | MBD5 | 0.566 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes