hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08014.1
Complex Portal: CPX-20616
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM143 | Transmembrane protein 143 | 5 | UniProt NCBI |
| SLITRK5 | SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11) | 5 | UniProt NCBI |
| SLC27A1 | Long-chain fatty acid transport protein 1 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Fatty acid transport protein 1) (FATP-1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 1) (Very long-chain acyl-CoA synthetase) (EC 6.2.1.-) | 5 | UniProt NCBI |
| ELOVL2 | Very long chain fatty acid elongase 2 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Elongation of very long chain fatty acids protein 2) (Very long chain 3-ketoacyl-CoA synthase 2) (Very long chain 3-oxoacyl-CoA synthase 2) | 5 | UniProt NCBI |
| ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Membrane component chromosome 6 surface marker 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form] [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)] | 5 | UniProt NCBI |
| SLC39A4 | Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4) | 5 | UniProt NCBI |
| HAS3 | Hyaluronan synthase 3 (EC 2.4.1.212) (Hyaluronate synthase 3) (Hyaluronic acid synthase 3) (HA synthase 3) | 5 | UniProt NCBI |
| PIGW | Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3.-.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004379 | 0.00962678270997 | 0.375 | ENPP1 SLC39A4 PIGW | Abnormality of alkaline phosphatase level |
| CORUM:7486 | 0.0499436884912 | 0.125 | HAS3 | HAS2-HAS3 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TMEM143 | SLC39A4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| SLC39A4 | HAS3 | 0.984 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SLC39A4 | PIGW | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC27A1 | SLC39A4 | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ELOVL2 | SLC39A4 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ENPP1 | SLC39A4 | 0.963 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLITRK5 | SLC39A4 | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ENPP1 | TMEM143 | 0.696 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TMEM143 | HAS3 | 0.675 | bioplex3_WMM WMM_only | ||
| ELOVL2 | PIGW | 0.659 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC27A1 | HAS3 | 0.587 | bioplex3_WMM WMM_only | ||
| SLC27A1 | TMEM143 | 0.33 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TMEM143 | PIGW | 0.207 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TMEM143 | ELOVL2 | 0.158 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC27A1 | ELOVL2 | 0.121 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP1 | ELOVL2 | 0.116 | 0.026 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEM143 | SLITRK5 | 0.097 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLITRK5 | PIGW | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC27A1 | PIGW | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ENPP1 | PIGW | 0.057 | bioplex_WMM bioplex3_WMM WMM_only | ||
| HAS3 | PIGW | 0.046 | bioplex3_WMM WMM_only | ||
| SLC27A1 | ENPP1 | 0.045 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP1 | SLITRK5 | 0.043 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELOVL2 | HAS3 | 0.042 | bioplex3_WMM WMM_only | ||
| SLC27A1 | SLITRK5 | 0.041 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ENPP1 | HAS3 | 0.025 | bioplex3_WMM WMM_only | ||
| SLITRK5 | HAS3 | 0.024 | bioplex3_WMM WMM_only | ||
| ELOVL2 | SLITRK5 | 0.019 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes