hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08026.1
Complex Portal: CPX-18546
Confidence: High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) | 5 | UniProt   NCBI |
CCNB2 | G2/mitotic-specific cyclin-B2 | 5 | UniProt   NCBI |
CKS2 | Cyclin-dependent kinases regulatory subunit 2 (CKS-2) | 4 | UniProt   NCBI |
TRIM49 | Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific RING-finger protein) | 4 | UniProt   NCBI |
EP300 | Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-) | 5 | UniProt   NCBI |
SKP2 | S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2) | 5 | UniProt   NCBI |
RBL2 | Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2) | 5 | UniProt   NCBI |
CDT1 | DNA replication factor Cdt1 (Double parked homolog) (DUP) | 5 | UniProt   NCBI |
CKS1B | Cyclin-dependent kinases regulatory subunit 1 (CKS-1) | 5 | UniProt   NCBI |
RBL1 | Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) | 5 | UniProt   NCBI |
SCAPER | S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) | 5 | UniProt   NCBI |
CREBBP | CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) | 5 | UniProt   NCBI |
CCNA2 | Cyclin-A2 (Cyclin-A) (Cyclin A) | 5 | UniProt   NCBI |
CCNA1 | Cyclin-A1 | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:04110 | 1.63391689661e-16 | 0.769230769231 | EP300 CCNA1 CCNB2 RBL2 RBL1 CREBBP SKP2 PKMYT1 CCNA2 CDT1 | Cell cycle |
  WP:WP179 | 1.79360947316e-12 | 0.615384615385 | EP300 CCNB2 RBL2 CCNA1 SKP2 PKMYT1 CCNA2 RBL1 | Cell cycle |
  REAC:R-HSA-69278 | 2.37786567164e-10 | 0.769230769231 | EP300 CCNA1 CKS1B CCNB2 RBL2 RBL1 SKP2 PKMYT1 CCNA2 CDT1 | Cell Cycle, Mitotic |
  REAC:R-HSA-69206 | 1.67900190586e-09 | 0.538461538462 | CCNA1 CKS1B SKP2 RBL1 CCNA2 RBL2 CDT1 | G1/S Transition |
  REAC:R-HSA-1640170 | 1.87165468276e-09 | 0.769230769231 | EP300 CCNA1 CKS1B CCNB2 RBL2 RBL1 SKP2 PKMYT1 CCNA2 CDT1 | Cell Cycle |
  REAC:R-HSA-453279 | 4.02136233978e-09 | 0.538461538462 | CCNA1 CKS1B SKP2 RBL1 CCNA2 RBL2 CDT1 | Mitotic G1 phase and G1/S transition |
  KEGG:05203 | 4.44531607983e-09 | 0.538461538462 | EP300 RBL2 CCNA1 CREBBP SKP2 CCNA2 RBL1 | Viral carcinogenesis |
  REAC:R-HSA-6791312 | 7.59681560682e-08 | 0.384615384615 | EP300 CCNA2 CCNA1 RBL1 RBL2 | TP53 Regulates Transcription of Cell Cycle Genes |
  REAC:R-HSA-69242 | 6.64075162689e-07 | 0.461538461538 | CKS1B SKP2 CDT1 CCNA2 RBL2 CCNA1 | S Phase |
  REAC:R-HSA-69273 | 1.28710141022e-06 | 0.307692307692 | PKMYT1 CCNA2 CCNA1 CCNB2 | Cyclin A/B1/B2 associated events during G2/M transition |
  REAC:R-HSA-1538133 | 1.52036969776e-06 | 0.307692307692 | RBL2 CCNA1 RBL1 CCNA2 | G0 and Early G1 |
  REAC:R-HSA-69202 | 1.66809915998e-06 | 0.384615384615 | SKP2 CCNA2 CCNA1 CKS1B RBL2 | Cyclin E associated events during G1/S transition |
  KEGG:04068 | 1.77140966758e-06 | 0.384615384615 | RBL2 CCNB2 CREBBP SKP2 EP300 | FoxO signaling pathway |
  REAC:R-HSA-69205 | 1.78390160965e-06 | 0.307692307692 | RBL2 CCNA1 CDT1 RBL1 | G1/S-Specific Transcription |
  REAC:R-HSA-69656 | 1.88564402368e-06 | 0.384615384615 | SKP2 CCNA2 CCNA1 CKS1B RBL2 | Cyclin A:Cdk2-associated events at S phase entry |
  WP:WP366 | 4.69378714544e-06 | 0.384615384615 | RBL2 CCNB2 CREBBP RBL1 EP300 | TGF beta signaling pathway |
  KEGG:04218 | 5.19732993245e-06 | 0.384615384615 | CCNB2 CCNA2 CCNA1 RBL1 RBL2 | Cellular senescence |
  KEGG:05165 | 5.4910288741e-06 | 0.461538461538 | EP300 CCNA2 RBL1 CREBBP RBL2 CCNA1 | Human papillomavirus infection |
  REAC:R-HSA-69236 | 1.64324396853e-05 | 0.307692307692 | SKP2 CKS1B RBL1 RBL2 | G1 Phase |
  REAC:R-HSA-69231 | 1.64324396853e-05 | 0.307692307692 | SKP2 CKS1B RBL1 RBL2 | Cyclin D associated events in G1 |
  GO:0044770 | 2.517369168e-05 | 0.615384615385 | CCNB2 CCNA1 RBL2 CDT1 SKP2 PKMYT1 CCNA2 RBL1 | cell cycle phase transition |
  KEGG:05166 | 2.92509551794e-05 | 0.384615384615 | CCNB2 CCNA2 CCNA1 CREBBP EP300 | Human T-cell leukemia virus 1 infection |
  KEGG:04914 | 3.62278994384e-05 | 0.307692307692 | PKMYT1 CCNA2 CCNA1 CCNB2 | Progesterone-mediated oocyte maturation |
  REAC:R-HSA-187577 | 4.87657023151e-05 | 0.307692307692 | SKP2 CCNA1 CKS1B CCNA2 | SCF(Skp2)-mediated degradation of p27/p21 |
  GO:0000278 | 5.05335215145e-05 | 0.692307692308 | CCNB2 CCNA1 CKS1B RBL2 RBL1 SKP2 PKMYT1 CCNA2 CDT1 | mitotic cell cycle |
  REAC:R-HSA-3700989 | 5.98511975082e-05 | 0.461538461538 | EP300 CCNA2 RBL1 CREBBP RBL2 CCNA1 | Transcriptional Regulation by TP53 |
  KEGG:05200 | 6.39114884851e-05 | 0.461538461538 | EP300 CKS1B CCNA2 CREBBP SKP2 CCNA1 | Pathways in cancer |
  REAC:R-HSA-156711 | 6.79304263505e-05 | 0.230769230769 | PKMYT1 EP300 CCNB2 | Polo-like kinase mediated events |
  REAC:R-HSA-1362300 | 6.79304263505e-05 | 0.230769230769 | RBL2 RBL1 CCNA2 | Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 |
  WP:WP2446 | 8.964186556e-05 | 0.307692307692 | CCNB2 CCNA2 CDT1 SKP2 | Retinoblastoma gene in cancer |
  REAC:R-HSA-68949 | 9.12418024467e-05 | 0.307692307692 | SKP2 CCNA1 CDT1 CCNA2 | Orc1 removal from chromatin |
  REAC:R-HSA-6804114 | 0.00010141817735 | 0.230769230769 | EP300 RBL1 RBL2 | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest |
  REAC:R-HSA-69275 | 0.000110897515521 | 0.384615384615 | PKMYT1 CCNA2 CCNA1 EP300 CCNB2 | G2/M Transition |
  REAC:R-HSA-453274 | 0.000116848819066 | 0.384615384615 | PKMYT1 CCNA2 CCNA1 EP300 CCNB2 | Mitotic G2-G2/M phases |
  CORUM:5144 | 0.00012303818858 | 0.153846153846 | CCNA2 RBL1 | E2F1-p107-cyclinA complex |
  CORUM:1661 | 0.00012303818858 | 0.153846153846 | CCNA2 RBL1 | E2F4-p107-cyclinA complex |
  CORUM:571 | 0.00012303818858 | 0.153846153846 | EP300 CREBBP | p300-CBP-p270 complex |
  CORUM:4 | 0.00012303818858 | 0.153846153846 | EP300 CREBBP | Multisubunit ACTR coactivator complex |
  REAC:R-HSA-69052 | 0.000251770237447 | 0.307692307692 | SKP2 CCNA1 CDT1 CCNA2 | Switching of origins to a post-replicative state |
  GO:0044772 | 0.000253297847694 | 0.538461538462 | CCNB2 RBL2 CCNA1 SKP2 CCNA2 PKMYT1 RBL1 | mitotic cell cycle phase transition |
  KEGG:05161 | 0.000384717586203 | 0.307692307692 | EP300 CCNA1 CREBBP CCNA2 | Hepatitis B |
  GO:1903047 | 0.000402575460606 | 0.615384615385 | CCNB2 CCNA1 RBL2 CDT1 SKP2 PKMYT1 CCNA2 RBL1 | mitotic cell cycle process |
  CORUM:3036 | 0.00040971577212 | 0.153846153846 | SKP2 CKS1B | Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) |
  CORUM:1471 | 0.00040971577212 | 0.153846153846 | EP300 RBL2 | pRb2/p130-multimolecular complex (RB2, E2F5, HDAC1, SUV39H1, P300) |
  CORUM:2638 | 0.00040971577212 | 0.153846153846 | EP300 CREBBP | HES1 promoter corepressor complex |
  REAC:R-HSA-170145 | 0.000598382447191 | 0.153846153846 | CCNA2 CCNA1 | Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes |
  CORUM:5118 | 0.000614265253436 | 0.153846153846 | EP300 RBL2 | RBL2 complex (E2F4, E2F5, HDAC1, SUV39H1, P300, RBL2) |
  CORUM:3015 | 0.000614265253436 | 0.153846153846 | SKP2 CKS1B | p27-cyclinE-Cdk2 - Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) complex |
  CORUM:6444 | 0.000614265253436 | 0.153846153846 | RBL2 RBL1 | SMAR1-HDAC1-SIN3A-SIN3B-p107-p130 repressor complex |
  HP:0001042 | 0.000760826170135 | 0.153846153846 | EP300 CREBBP | High axial triradius |
  HP:0008107 | 0.000760826170135 | 0.153846153846 | EP300 CREBBP | Plantar crease between first and second toes |
  HP:0005895 | 0.000760826170135 | 0.153846153846 | EP300 CREBBP | Radial deviation of thumb terminal phalanx |
  HP:0034227 | 0.000760826170135 | 0.153846153846 | EP300 CREBBP | Aortic isthmus hypoplasia |
  REAC:R-HSA-69239 | 0.000771280408265 | 0.307692307692 | SKP2 CCNA1 CDT1 CCNA2 | Synthesis of DNA |
  CORUM:570 | 0.0008595398098 | 0.153846153846 | EP300 CREBBP | p300-CBP-p270-SWI/SNF complex |
  REAC:R-HSA-3134973 | 0.00199260676058 | 0.153846153846 | EP300 CREBBP | LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production |
  REAC:R-HSA-69478 | 0.00199260676058 | 0.153846153846 | PKMYT1 CCNB2 | G2/M DNA replication checkpoint |
  REAC:R-HSA-68911 | 0.00199260676058 | 0.153846153846 | CCNA2 CCNA1 | G2 Phase |
  GO:0016538 | 0.00206669740672 | 0.307692307692 | CCNB2 CCNA1 CKS1B CCNA2 | cyclin-dependent protein serine/threonine kinase regulator activity |
  HP:0008752 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Laryngeal cartilage malformation |
  HP:0000756 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Agoraphobia |
  HP:0006200 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Widened distal phalanges |
  HP:0005363 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Humoral immunodeficiency |
  HP:5200232 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Phobia |
  HP:0005322 | 0.00228133307992 | 0.153846153846 | EP300 CREBBP | Prominent nasal septum |
  REAC:R-HSA-212436 | 0.00263447397095 | 0.538461538462 | EP300 RBL2 CCNA1 CREBBP SKP2 CCNA2 RBL1 | Generic Transcription Pathway |
  KEGG:04350 | 0.00319307127413 | 0.230769230769 | EP300 RBL1 CREBBP | TGF-beta signaling pathway |
  REAC:R-HSA-69306 | 0.00348678391218 | 0.307692307692 | SKP2 CCNA1 CDT1 CCNA2 | DNA Replication |
  REAC:R-HSA-1234158 | 0.00418027557771 | 0.153846153846 | EP300 CREBBP | Regulation of gene expression by Hypoxia-inducible Factor |
  HP:0010775 | 0.0045603764747 | 0.153846153846 | EP300 CREBBP | Vascular ring |
  HP:0410266 | 0.0045603764747 | 0.153846153846 | EP300 CREBBP | Visceral hemangioma |
  HP:0001128 | 0.0045603764747 | 0.153846153846 | EP300 CREBBP | Trichiasis |
  HP:0031207 | 0.0045603764747 | 0.153846153846 | EP300 CREBBP | Hepatic hemangioma |
  HP:0011087 | 0.0045603764747 | 0.153846153846 | EP300 CREBBP | Talon cusp |
  REAC:R-HSA-9614085 | 0.0049922040089 | 0.230769230769 | EP300 CREBBP RBL2 | FOXO-mediated transcription |
  REAC:R-HSA-73857 | 0.00544250481316 | 0.538461538462 | EP300 RBL2 CCNA1 CREBBP SKP2 CCNA2 RBL1 | RNA Polymerase II Transcription |
  REAC:R-HSA-9818028 | 0.00557090384564 | 0.153846153846 | EP300 CREBBP | NFE2L2 regulates pentose phosphate pathway genes |
  WP:WP53 | 0.00560333986549 | 0.153846153846 | RBL2 RBL1 | ID signaling pathway |
  GO:0000307 | 0.00625701956595 | 0.307692307692 | CCNB2 CCNA1 CKS1B CCNA2 | cyclin-dependent protein kinase holoenzyme complex |
  GO:0007049 | 0.00646947319099 | 0.692307692308 | CCNB2 CCNA1 CKS1B RBL2 RBL1 SKP2 PKMYT1 CCNA2 CDT1 | cell cycle |
  CORUM:5614 | 0.00695708221026 | 0.153846153846 | RBL2 RBL1 | Emerin complex 32 |
  HP:0033777 | 0.00759681327472 | 0.153846153846 | EP300 CREBBP | Supernumerary cusp |
  HP:0030421 | 0.00759681327472 | 0.153846153846 | EP300 CREBBP | Epididymal neoplasm |
  HP:0009715 | 0.00759681327472 | 0.153846153846 | EP300 CREBBP | Papillary cystadenoma of the epididymis |
  REAC:R-HSA-9617629 | 0.00894425512963 | 0.153846153846 | EP300 CREBBP | Regulation of FOXO transcriptional activity by acetylation |
  REAC:R-HSA-8866907 | 0.00894425512963 | 0.153846153846 | EP300 CREBBP | Activation of the TFAP2 (AP-2) family of transcription factors |
  REAC:R-HSA-210744 | 0.010926381878 | 0.153846153846 | EP300 CREBBP | Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells |
  REAC:R-HSA-8941856 | 0.010926381878 | 0.153846153846 | EP300 CREBBP | RUNX3 regulates NOTCH signaling |
  HP:0100852 | 0.0113895015741 | 0.153846153846 | EP300 CREBBP | Abnormal fear-induced behavior |
  HP:0002700 | 0.0113895015741 | 0.153846153846 | EP300 CREBBP | Large foramen magnum |
  HP:0004411 | 0.0113895015741 | 0.153846153846 | EP300 CREBBP | Deviated nasal septum |
  REAC:R-HSA-74160 | 0.0123811504483 | 0.538461538462 | EP300 RBL2 CCNA1 CREBBP SKP2 CCNA2 RBL1 | Gene expression (Transcription) |
  REAC:R-HSA-5688426 | 0.0142368095397 | 0.307692307692 | EP300 CCNA2 CCNA1 SKP2 | Deubiquitination |
  WP:WP3657 | 0.0144668298298 | 0.153846153846 | EP300 CREBBP | Hematopoietic stem cell gene regulation by GABP alpha beta complex |
  REAC:R-HSA-174143 | 0.014731681941 | 0.230769230769 | SKP2 CCNA1 CCNA2 | APC/C-mediated degradation of cell cycle proteins |
  REAC:R-HSA-453276 | 0.014731681941 | 0.230769230769 | SKP2 CCNA1 CCNA2 | Regulation of mitotic cell cycle |
  REAC:R-HSA-6804116 | 0.0154800492167 | 0.153846153846 | CCNA2 CCNA1 | TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest |
  REAC:R-HSA-3371568 | 0.0154800492167 | 0.153846153846 | EP300 CREBBP | Attenuation phase |
  HP:0011335 | 0.01593730064 | 0.153846153846 | EP300 CREBBP | Frontal hirsutism |
  HP:0030434 | 0.01593730064 | 0.153846153846 | EP300 CREBBP | Pilomatrixoma |
  WP:WP4673 | 0.0161599355539 | 0.230769230769 | EP300 CREBBP CCNA1 | Male infertility |
  REAC:R-HSA-918233 | 0.0180509953769 | 0.153846153846 | EP300 CREBBP | TRAF3-dependent IRF activation pathway |
  GO:0022402 | 0.0188869246022 | 0.615384615385 | CCNB2 CCNA1 RBL2 CDT1 SKP2 PKMYT1 CCNA2 RBL1 | cell cycle process |
  REAC:R-HSA-9013695 | 0.0208176207539 | 0.153846153846 | EP300 CREBBP | NOTCH4 Intracellular Domain Regulates Transcription |
  HP:0002341 | 0.0212390709115 | 0.153846153846 | EP300 CREBBP | Cervical cord compression |
  HP:0031251 | 0.0212390709115 | 0.153846153846 | EP300 CREBBP | Abnormal subclavian artery morphology |
  REAC:R-HSA-69620 | 0.0221658836763 | 0.307692307692 | PKMYT1 CCNA2 CCNA1 CCNB2 | Cell Cycle Checkpoints |
  REAC:R-HSA-9818027 | 0.0237796288966 | 0.153846153846 | EP300 CREBBP | NFE2L2 regulating anti-oxidant/detoxification enzymes |
  REAC:R-HSA-9614657 | 0.0237796288966 | 0.153846153846 | EP300 CREBBP | FOXO-mediated transcription of cell death genes |
  REAC:R-HSA-1368082 | 0.0237796288966 | 0.153846153846 | EP300 CREBBP | RORA activates gene expression |
  REAC:R-HSA-9755511 | 0.0259720077412 | 0.230769230769 | EP300 CREBBP SKP2 | KEAP1-NFE2L2 pathway |
  HP:0010314 | 0.0272936739987 | 0.153846153846 | EP300 CREBBP | Premature thelarche |
  KEGG:05169 | 0.0274490471376 | 0.230769230769 | SKP2 CCNA1 CCNA2 | Epstein-Barr virus infection |
  HP:0003042 | 0.0290064451946 | 0.230769230769 | EP300 CDT1 CREBBP | Elbow dislocation |
  REAC:R-HSA-1362277 | 0.0302886092005 | 0.153846153846 | RBL2 RBL1 | Transcription of E2F targets under negative control by DREAM complex |
  REAC:R-HSA-9793380 | 0.0302886092005 | 0.153846153846 | EP300 CREBBP | Formation of paraxial mesoderm |
  HP:0001956 | 0.0316097192986 | 0.230769230769 | EP300 SCAPER CREBBP | Truncal obesity |
  HP:0007086 | 0.0340999726817 | 0.153846153846 | EP300 CREBBP | Social and occupational deterioration |
  HP:0009714 | 0.0340999726817 | 0.153846153846 | EP300 CREBBP | Abnormal epididymis morphology |
  HP:0002697 | 0.0340999726817 | 0.153846153846 | EP300 CREBBP | Parietal foramina |
  WP:WP3414 | 0.0341762058176 | 0.153846153846 | EP300 CREBBP | Initiation of transcription and translation elongation at the HIV 1 LTR |
  REAC:R-HSA-5621575 | 0.0375755707785 | 0.153846153846 | EP300 CREBBP | CD209 (DC-SIGN) signaling |
  REAC:R-HSA-9013508 | 0.0375755707785 | 0.153846153846 | EP300 CREBBP | NOTCH3 Intracellular Domain Regulates Transcription |
  HP:0010562 | 0.0416568309099 | 0.153846153846 | EP300 CREBBP | Keloids |
  HP:0000273 | 0.0416568309099 | 0.153846153846 | EP300 CREBBP | Facial grimacing |
  HP:0000321 | 0.0416568309099 | 0.153846153846 | EP300 CREBBP | Square face |
  WP:WP4241 | 0.0416894057602 | 0.153846153846 | EP300 CREBBP | Type 2 papillary renal cell carcinoma |
  HP:0030310 | 0.0419228733309 | 0.230769230769 | EP300 CDT1 CREBBP | Upper extremity joint dislocation |
  KEGG:04330 | 0.0460573567798 | 0.153846153846 | EP300 CREBBP | Notch signaling pathway |
  REAC:R-HSA-3371571 | 0.0499595654642 | 0.153846153846 | EP300 CREBBP | HSF1-dependent transactivation |
  REAC:R-HSA-171319 | 0.0499595654642 | 0.153846153846 | CCNA2 CCNA1 | Telomere Extension By Telomerase |
  HP:0010066 | 0.0499631138006 | 0.153846153846 | EP300 CREBBP | Duplication of phalanx of hallux |
  HP:0010181 | 0.0499631138006 | 0.153846153846 | EP300 CREBBP | Duplication of phalanx of toe |
  HP:0012304 | 0.0499631138006 | 0.153846153846 | EP300 CREBBP | Hypoplastic aortic arch |
  CORUM:5556 | 0.0499717467432 | 0.0769230769231 | CCNA2 | CDK2-CCNA2 complex |
  CORUM:5320 | 0.0499717467432 | 0.0769230769231 | SKP2 | CDH1-SKP2 complex |
  CORUM:5319 | 0.0499717467432 | 0.0769230769231 | CKS1B | CDH1-CKS1B complex |
  CORUM:5198 | 0.0499717467432 | 0.0769230769231 | CREBBP | CBP-RARA-RXRA-DNA complex, ligand stimulated |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
---|---|---|---|---|
 SKP2 |  CKS1B | 1.0 | 0.138           |
structurally_consistent (dimer)        
|
 SKP2 |  CCNA2 | 1.0 | 0.284           |
mutually_exclusive (P11802)        
structurally_consistent (dimer)         |
 CCNA2 |  CKS1B | 1.0 | 0.222           |          |
 RBL2 |  CCNA2 | 1.0 | 0.118           |          |
 PKMYT1 |  CCNB2 | 1.0 | 0.214           |
structurally_consistent (dimer)        
|
 CCNB2 |  CKS2 | 1.0 | 0.134           |          |
 RBL1 |  CCNA2 | 1.0 | 0.296           |
structurally_consistent (dimer)        
|
 CDT1 |  CCNA2 | 1.0 | 0.128           |          |
 SCAPER |  CCNA2 | 0.999 | 0.176           |
structurally_consistent (dimer)        
|
 CKS2 |  CCNA2 | 0.999 | 0.206           |
structurally_consistent (dimer)        
|
 CCNB2 |  CKS1B | 0.999 | 0.22           |          |
 EP300 |  CREBBP | 0.999 | 0.476           |          |
 CKS2 |  CKS1B | 0.998 | 0.584           |
structurally_consistent (dimer)        
|
 CKS2 |  SKP2 | 0.998 | 0.098           |          |
 PKMYT1 |  CCNA2 | 0.998 | 0.12           |          |
 SKP2 |  CDT1 | 0.998 | 0.21           |          |
 RBL2 |  RBL1 | 0.996 | 0.118           |          |
 CCNB2 |  CCNA2 | 0.996 | 0.28           |
structurally_consistent (dimer)        
|
 CREBBP |  CCNA2 | 0.996 | 0.236473684211           |          |
 PKMYT1 |  CKS1B | 0.996 | 0.064           |
structurally_consistent (dimer)        
|
 EP300 |  CCNA2 | 0.995 | 0.266809384164           |          |
 CDT1 |  CKS1B | 0.995 | 0.19           |          |
 CCNB2 |  SKP2 | 0.994 | 0.322           |
mutually_exclusive (P20248)        
|
 CCNA2 |  CCNA1 | 0.993 |            |
structurally_consistent (dimer)        
|
 PKMYT1 |  CKS2 | 0.984 | 0.056           |          |
 PKMYT1 |  SKP2 | 0.969 | 0.184           |
mutually_exclusive (P61024)        
|
 CKS1B |  TRIM49 | 0.968 |            |
structurally_consistent (dimer)        
|
 PKMYT1 |  CDT1 | 0.958 | 0.116           |
mutually_exclusive (P14635)        
|
 RBL2 |  CKS2 | 0.953 | 0.046           |
mutually_exclusive (P24941)        
|
 RBL2 |  CKS1B | 0.949 | 0.052           |
mutually_exclusive (P24941)        
|
 RBL2 |  SKP2 | 0.947 | 0.098           |          |
 SKP2 |  TRIM49 | 0.943 |            |          |
 CKS2 |  CDT1 | 0.93 | 0.088           |
mutually_exclusive (P06493)        
|
 EP300 |  RBL1 | 0.877 | 0.323130434783           |          |
 RBL2 |  CREBBP | 0.846 | 0.362           |          |
 RBL1 |  CREBBP | 0.828 | 0.307536384977           |          |
 CDT1 |  SCAPER | 0.809 | 0.178           |          |
 RBL1 |  CKS2 | 0.798 | 0.142           |
structurally_consistent (P20248)        
|
 RBL1 |  CKS1B | 0.798 | 0.112           |          |
 SKP2 |  SCAPER | 0.788 | 0.154           |          |
 RBL1 |  SKP2 | 0.784 | 0.136           |          |
 PKMYT1 |  SCAPER | 0.704 | 0.118           |          |
 RBL1 |  SCAPER | 0.625 | 0.112           |          |
 RBL2 |  SCAPER | 0.611 | 0.15           |          |
 RBL1 |  CDT1 | 0.572 | 0.134           |          |
 RBL2 |  CDT1 | 0.572 | 0.062           |          |
 CKS2 |  SCAPER | 0.563 | 0.032           |          |
 SCAPER |  CKS1B | 0.548 | 0.114           |          |
 SCAPER |  CCNA1 | 0.487 |            |          |
 EP300 |  RBL2 | 0.482 | 0.226           |          |
 CDT1 |  CCNA1 | 0.35 |            |          |
 CREBBP |  CCNA1 | 0.333 |            |          |
 CCNB2 |  CDT1 | 0.291 | 0.208695652174           |          |
 CCNA1 |  CKS1B | 0.262 |            |          |
 CKS2 |  CCNA1 | 0.218 |            |          |
 EP300 |  CCNB2 | 0.208 | 0.232           |          |
 RBL2 |  CCNB2 | 0.19 | 0.088           |
mutually_exclusive (P24941)        
|
 EP300 |  CKS1B | 0.177 | 0.022           |          |
 RBL1 |  CCNA1 | 0.172 |            |          |
 SCAPER |  CREBBP | 0.172 | 0.208           |          |
 EP300 |  CCNA1 | 0.172 |            |          |
 RBL2 |  CCNA1 | 0.172 |            |          |
 PKMYT1 |  CCNA1 | 0.164 |            |          |
 EP300 |  SCAPER | 0.164 | 0.27           |          |
 RBL1 |  PKMYT1 | 0.16 | 0.178           |          |
 EP300 |  CKS2 | 0.16 | 0.024           |          |
 RBL1 |  CCNB2 | 0.158 | 0.314           |          |
 SKP2 |  CCNA1 | 0.156 |            |          |
 PKMYT1 |  CREBBP | 0.15 | 0.146           |          |
 CDT1 |  CREBBP | 0.143 | 0.248           |          |
 EP300 |  CDT1 | 0.143 | 0.26           |          |
 EP300 |  SKP2 | 0.12 | 0.280075471698           |          |
 CKS2 |  CREBBP | 0.12 | 0.016           |          |
 CREBBP |  CKS1B | 0.12 | 0.048           |          |
 RBL2 |  PKMYT1 | 0.114 | 0.062           |          |
 SKP2 |  CREBBP | 0.111 | 0.260784313725           |          |
 CCNB2 |  CCNA1 | 0.078 |            |          |
 CCNB2 |  CREBBP | 0.074 | 0.376           |          |
 EP300 |  PKMYT1 | 0.066 | 0.154           |          |
 CCNB2 |  SCAPER | 0.011 | 0.13           |          |
Related Complexes