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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_08039.1
Confidence:
High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
FBXO40
F-box only protein 40 (Muscle disease-related protein)
4
UniProt
NCBI
IQGAP1
Ras GTPase-activating-like protein IQGAP1 (p195)
5
UniProt
NCBI
IQGAP2
Ras GTPase-activating-like protein IQGAP2
5
UniProt
NCBI
MYH14
Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C)
5
UniProt
NCBI
MYL12B
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
5
UniProt
NCBI
MYL3
Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)
5
UniProt
NCBI
MYL6
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
5
UniProt
NCBI
Showing 1 to 7 of 7 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
REAC:R-HSA-416572
1.25938591632e-05
0.428571428571
MYH14 MYL6 MYL12B
Sema4D induced cell migration and growth-cone collapse
REAC:R-HSA-5625900
1.25938591632e-05
0.428571428571
MYH14 MYL6 MYL12B
RHO GTPases activate CIT
REAC:R-HSA-5627117
1.25938591632e-05
0.428571428571
MYH14 MYL6 MYL12B
RHO GTPases Activate ROCKs
REAC:R-HSA-195258
1.29732652309e-05
0.714285714286
MYH14 IQGAP2 MYL6 IQGAP1 MYL12B
RHO GTPase Effectors
REAC:R-HSA-5627123
1.48132609528e-05
0.428571428571
MYH14 MYL6 MYL12B
RHO GTPases activate PAKs
REAC:R-HSA-400685
2.29983491089e-05
0.428571428571
MYH14 MYL6 MYL12B
Sema4D in semaphorin signaling
KEGG:04814
2.58938574941e-05
0.571428571429
MYH14 MYL6 MYL3 MYL12B
Motor proteins
REAC:R-HSA-3928663
3.374300022e-05
0.428571428571
MYH14 MYL6 MYL12B
EPHA-mediated growth cone collapse
KEGG:04810
5.44074779948e-05
0.571428571429
MYH14 MYL12B IQGAP1 IQGAP2
Regulation of actin cytoskeleton
GO:0015629
9.54784787211e-05
0.857142857143
MYH14 IQGAP2 MYL12B MYL6 MYL3 IQGAP1
actin cytoskeleton
Showing 1 to 10 of 31 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Evidence
?
MYH14
MYL6
0.995
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
IQGAP2
MYL6
0.995
0.128
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM
MYL6
MYL12B
0.993
0.146
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
MYL3
IQGAP1
0.992
0.174
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
MYL6
IQGAP1
0.991
0.252624
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM
MYH14
MYL12B
0.99
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only
MYL12B
IQGAP1
0.984
0.544
hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only
MYL6
MYL3
0.975
0.09
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
FBXO40
MYH14
0.963
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MYH14
MYL3
0.947
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
Showing 1 to 10 of 19 entries
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Related Complexes
Genename
Complexes
MYH14
huMAP3_02178.1
huMAP3_03169.1
huMAP3_03184.1
huMAP3_05543.1
huMAP3_07968.1
huMAP3_08039.1
huMAP3_09441.1
huMAP3_10270.1
huMAP3_15295.1
FBXO40
huMAP3_02178.1
huMAP3_08039.1
huMAP3_10270.1
huMAP3_15295.1
MYL6
huMAP3_02370.1
huMAP3_03169.1
huMAP3_05350.1
huMAP3_05543.1
huMAP3_06098.1
huMAP3_06531.1
huMAP3_07968.1
huMAP3_08039.1
huMAP3_09441.1
huMAP3_10270.1
MYL12B
huMAP3_02370.1
huMAP3_06098.1
huMAP3_06531.1
huMAP3_08039.1
huMAP3_09542.1
huMAP3_10270.1
MYL3
huMAP3_02370.1
huMAP3_03169.1
huMAP3_05350.1
huMAP3_05543.1
huMAP3_06098.1
huMAP3_06531.1
huMAP3_08039.1
huMAP3_09789.1
huMAP3_10270.1
huMAP3_15295.1
IQGAP2
huMAP3_00809.1
huMAP3_02370.1
huMAP3_02834.1
huMAP3_05543.1
huMAP3_06531.1
huMAP3_08039.1
huMAP3_08200.1
huMAP3_09441.1
huMAP3_10270.1
huMAP3_10273.1
huMAP3_10665.1
huMAP3_12336.1
huMAP3_13036.1
IQGAP1
huMAP3_02370.1
huMAP3_05543.1
huMAP3_06098.1
huMAP3_06445.1
huMAP3_06531.1
huMAP3_08039.1
huMAP3_10270.1