hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08074.1
Complex Portal: CPX-17867
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MECP2 | Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2) | 5 | UniProt NCBI |
| NMNAT1 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) | 5 | UniProt NCBI |
| ZC3H4 | Zinc finger CCCH domain-containing protein 4 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:5200017 | 0.0136509708315 | 0.666666666667 | MECP2 NMNAT1 | Abnormal movements of face and head |
| WP:WP5420 | 0.0379798583444 | 0.666666666667 | MECP2 NMNAT1 | ADHD and autism ASD linked metabolic pathways and SNP |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MECP2 | ZC3H4 | 0.977 | 0.104 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| MECP2 | NMNAT1 | 0.964 | 0.026 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZC3H4 | NMNAT1 | 0.117 | 0.028 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes