hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08079.1
Complex Portal: CPX-13255
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFT2D2 | Vesicle transport protein SFT2B (SFT2 domain-containing protein 2) | 5 | UniProt NCBI |
| SPOP | Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1) | 5 | UniProt NCBI |
| XCL1 | Lymphotactin (ATAC) (C motif chemokine 1) (Cytokine SCM-1) (Lymphotaxin) (SCM-1-alpha) (Small-inducible cytokine C1) (XC chemokine ligand 1) | 5 | UniProt NCBI |
| KPNA5 | Importin subunit alpha-6 (Karyopherin subunit alpha-5) | 5 | UniProt NCBI |
| SPOPL | Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4249 | 0.00389862536801 | 0.4 | SPOP SPOPL | Hedgehog signaling pathway |
| KEGG:04340 | 0.00447375439216 | 0.4 | SPOP SPOPL | Hedgehog signaling pathway |
| REAC:R-HSA-5632684 | 0.0440242300692 | 0.4 | SPOP SPOPL | Hedgehog 'on' state |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SPOPL | SPOP | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SPOPL | KPNA5 | 0.996 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPOP | KPNA5 | 0.994 | 0.066 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| SFT2D2 | SPOPL | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| XCL1 | SPOPL | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SFT2D2 | XCL1 | 0.415 | bioplex3_WMM WMM_only | ||
| SFT2D2 | SPOP | 0.113 | 0.104 | bioplex3_WMM WMM_only | |
| XCL1 | SPOP | 0.078 | bioplex3_WMM WMM_only | ||
| SFT2D2 | KPNA5 | 0.076 | 0.112 | bioplex3_WMM WMM_only | |
| XCL1 | KPNA5 | 0.074 | bioplex3_WMM WMM_only |
Related Complexes